Neuroscience Anatomy Flashcards

1
Q

Somatic Nervous System

A

peripheral nerve fibers send sensory information to the CNS
• motor nerve fibers send information to skeletal muscles
• somatic motor neurons travel directly to skeletal muscle without intervening synapses
controls voluntary movements and provides the ability to sense touch, smell,
sight, taste, and sound
• all five senses are influenced by the SNS

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2
Q

Limbic System

A

corpus collosum, olfactory tract, mammillary bodies, fornix, thalamic nuclei, amygdala, hippocampus, aprahippocampal gyrus, cingulate gyrus, hypothalamic nuclei

  • involved in the control and expression of mood and emotion, processing and storage of recent memory, olfaction, control of appetite, and emotional responses to food
  • lesions to the limbic system can also result in a variety of behaviors including aggression, extreme fearfulness, altered sexual behavior, and changes in motivation
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3
Q

Frontal lobe (function and impairment)

A

Function:
* voluntary movement, intellect, orientation
* Broca’s area (typically located in the left hemisphere): speech, concentration
personality, temper, judgment, executive functions, reasoning, behavior, self-awareness

Impairment:
* contralateral weakness
* perseveration, inattention
* personality changes, antisocial behavior
* Broca’s aphasia (expressive deficits)
* delayed or poor initiation, emotional lability

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4
Q

Parietal lobe

A

Function:
*associated with sensation of touch, kinesthesia, perception of vibration, and temperature
* receives information from other areas of the brain regarding hearing, vision, motor, sensory, and memory
* interprets language and words
* spatial and visual perception
* provides meaning for objects

Impairment:
* dominant hemisphere (typically located in the left hemisphere):
agraphia, alexia, agnosia
* non-dominant hemisphere (typically located in the right hemisphere): dressing apraxia, anosognosia
* contralateral sensory deficits
* impaired language comprehension

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5
Q

Temporal lobe

A

Function:
primary auditory processing and olfaction
* Wernicke’s area (typically located in the left hemisphere): ability to understand and produce meaningful speech, verbal and general memory, assists with understanding language
*the rear of the temporal lobe enables humans to interpret other people’s emotions and reactions

Impairment:
* learning deficits
* Wernicke’s aphasia (receptive deficits)
* antisocial, aggressive behaviors
* difficulty with facial recognition
* difficulty with memory, memory lOss
* inability to categorize objects

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6
Q

Occipital Lobe

A

Function:
* main processing center for visual information
* processes visual information regarding colors, light, and shapes
* judgment of distance, seeing in three dimensions

Impairment:
* homonymous hemianopsia
* impaired extraocular muscle movement and visual deficits
* reading and writing impairment
* cortical blindness with bilateral lobe involvement

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7
Q

What are the meninges

A

3 layers of connective tissue covering the brain and spinal cord.

Provide protection from contusion and infection.

There are blood vessels and cerebrospinal fluid (CSF) within the meninges.

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8
Q

What are the 3 types of meninges

A

*dura mater: outermost meninx; has four folds; lines the periosteum of the skull and protects the brain; subdural space separates this from the arachnoid mater

*arachnoid mater: the middle meninx; the arachnoid is impermeable; surrounds the brain in a loose manner; subarachnoid space separates this from the pia mater

  • pia mater: innermost meninx; covers the contours of the brain;
    forms the choroid plexus in the ventricular system
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9
Q

What are the dural spaces

A
  • epidural space: an area between the skull and outer dura mater that can be abnormally occupied; also the area in the spinal cord between the dura mater and the periosteum of the vertebrae
  • subdural space: the area between the dura and arachnoid meninges
  • subarachnoid space: the area between the arachnoid and pia mater that contains CSF and the circulatory system for the cerebral cortex
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10
Q

Cerebrospinal Fluid (CSF)

A
  • clear, fluid-like substance
  • cushions the brain and spinal cord from injury and provides mechanical buoyancy and support.
  • produced constantly: 500-700 ml/day.
  • Provides nutrition to the central nervous system, serves as a conduit for removal of metabolites, and is constantly being absorbed and replenished within the brain and spinal cord.
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11
Q

Blood brain barrier

A
  • consists of the meninges, protective glial cells, and capillary beds of the brain.
  • It is responsible for exchange of nutrients between the central nervous system and the vascular system.
  • Provides protection for the CNS by restricting certain molecules from crossing the barrier while others are able to do so freely.
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12
Q

Right hemisphere specialization/dominance

A
  • Nonverbal processing
  • Process information in a holistic manner
  • Artistic abilities
  • General concept comprehension
  • Hand-eye coordination
  • Spatial relationships
  • Kinesthetic awareness
  • Understand music
  • Understand nonverbal communication
  • Mathematical reasoning
  • Express negative emotions
  • Body image awareness
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13
Q

Left hemisphere specialization/dominance

A
  • Language
  • Sequence and perform movements
  • Understand language
  • Produce written and spoken language
  • Analytical
  • Controlled
  • Logical
  • Rational
  • Mathematical calculations
  • Express positive emotions such as love and happiness
  • Process verbally coded information in an organized, logical, and sequential manner
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14
Q

Hippocampus

A
  • in the lower temporal lobe
  • responsible for forming and storing new memories of personal hx and other declarative memory.
  • sends memories to appropriates areas of the cerebral hemispheres for long-term storage.
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15
Q

Basal Ganglia

A
  • includes: caudate, putamen, globus pallidus, substantia nigra, and subthalamic nuclei.
  • voluntary movement, regulation of ANS, posture, m tone, and control of motor responses
  • Dysfunction: PD, Huntington’s disease, tourette’s syndrome, ADD, Obsessive-compulsive disorder, and many addictions
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16
Q

Amygdala

A
  • in the temporal lobes
  • emotional and social processing.
  • Involved in fear and pleasure responses, arousal, processing of memory, and formation of emotional memories
17
Q

Thalamus

A
  • relay or processing station
  • coordinates sensory perception and mvmt with other parts of the brain and SC.
  • Receives info from cerebellum, BG, and all sensory pathways except olfactory tract.
  • Then relays to appropriate association cortex
  • can produce thalamic pain syndrome where there is spontaneous pain on the contralateral side of the body to the thalamic lesion.
18
Q

Hypothalamus

A
  • receives and integrates info from ANS and assists with regulating hormones
  • controls functions such as hunger, thirst, sexual behavior, and sleeping.
  • Regulates temperature, adrenal glands, pituitary gland, and other vital activities.

Impairments:
* Obesity, sexual disinterest, poor temperature control, and diabetes insipidus.

19
Q

Subthalamus

A
  • regulating movement produced by skeletal m.
  • Has association with the basal ganglia and substantia nigra.
20
Q

Epithalamus

A
  • pineal gland

*secretes melatonin and involved in circadian rhythm (internal clock), selected regulation of motor pathways, and emotions.

21
Q

Midbrain

A
  • large relay area for info passing from cerebrum, cerebellum, and SC
  • also reflex center for visual, auditory, and tactile responses
22
Q

Cerebellum

A
  • responsible for fine tuning of movement and assists with maintaining posture and balance, controlling m tone and positioning of the extremities in space
  • control ability to perform rapidly alternating movement
  • Damage to one side of cerebellum will produce IPSILATERAL deficits.
  • Lesion produces: ataxia, nystagmus, tremor, hypermetria, poor coordination, and deficits in postural reflexes, balance, and equilibrium.
23
Q

Pons

A
  • regulation of respiration rate and orientation of the head in relation to visual and auditory stimuli
  • CN V- CV VIII
24
Q

Medulla Oblongata

A
  • influences ANS and regulates respiration and HR.
  • reflex centers for vomiting, coughing, and sneezing are found in medulla.
  • responsible for relaying somatic sensory information for internal organs and the control of arousal and sleep
  • Damage produces contralateral impairment.
  • CN IX, X, XI, XII
25
Q

Anterior Cerebral Artery (ACA)

A
  • anterior frontal lobe
  • medial surface of frontal and parietal lobe
26
Q

Anterior Cerebral Artery (ACA) expected possible impairment based on extent of vascular involvement

A
  • Contralateral lower extremity motor and sensory involvement
  • Loss of bowel and bladder control
  • Loss of behavioral inhibition (personality changes)
  • Significant mental changes
  • Neglect
  • Aphasia
  • Apraxia and agraphia
  • Perseveration
  • Akinetic mutism with significant bilateral involvement
27
Q

Middle Cerebral Artery (ACA) supplies

A

Most of outer cerebrum
* Basal ganglia
* Posterior and anterior internal capsule
* Putamen
* Pallidum
* Lentiform nucleus

28
Q

Middle Cerebral Artery (MCA) expected possible impairment based on extent of vascular invovlement

A
  • Most common site of a CVA
  • Wernicke’s aphasia in dominant hemisphere
  • Homonymous hemianopsia
  • Apraxia
  • Flat affect with right hemisphere damage
  • Contralateral weakness and sensory loss of face and upper extremity with lesser involvement in the lower extremity
  • Impaired spatial relations
  • Anosognosia in non-dominant hemisphere
  • Impaired body schema
29
Q

Posterior Cerebral Artery (PCA) supplies

A

Most of outer cerebrum
* Basal ganglia
* Posterior and anterior internal capsule
* Putamen
* Pallidum
* Lentiform nucleus

30
Q

Posterior Cerebral Artery (PCA) expected possible impairment based on extent of vascular involvement

A
  • Contralateral pain and temperature sensory loss
  • Contralateral hemiplegia (central area), mild hemiparesis
  • Ataxia, athetosis or choreiform movement
    Quality of movement is impaired
  • Thalamic pain syndrome
  • Anomia
  • Prosopagnosia with occipital infarct
  • Hemiballismus
  • Visual agnosia
  • Homonymous hemianopsia
  • Memory impairment
  • Alexia, dyslexia
  • Cortical blindness from bilateral involvement
31
Q

Vertebral-basilar artery supplies

A
  • Lateral aspect of pons and midbrain together with superior surface of cerebellum
  • Cerebellum - branches from the basilar artery (posterior inferior cerebellar, anterior inferior cerebellar, and superior cerebellar arteries)
    . Medulla - posterior inferior cerebellar artery, smaller branches from the vertebral arteries . Pons - branches from the basilar artery . Midbrain and thalamus - posterior cerebral arteries . Occipital cortex - posterior cerebral artery, basilar artery
32
Q

Vertebral-basilar artery expected possible impairment based on extent of vascular involvement

A
  • Loss of consciousness
  • Hemiplegia or tetraplegia
  • Comatose or vegetative state
  • Inability to speak
  • Locked-in syndrome
  • Vertigo
  • Nystagmus
  • Dysphagia
  • Dysarthria
  • Syncope
  • Ataxia

Wallenberg syndrome secondary to lateral medullary infarct - ipsilateral facial pain and temperature impairment, ipsilateral ataxia, vertigo, contralateral pain and temperature impairment of the body.