neuraxial blocks part 2 Flashcards
4 key SE of neuraxial opioids
- pruritis
- urinary retention
- resp depression
- n/v
MOA of pruritis during neuraxial blockade
stimulation of opioid receptors in trigeminal nucleus or some other type of opioid triggered neural process
MOA of early versus late stage resp depression (most often both in hydrophilic)
early (<6h) results from systemic absorption
late (>6h) results from tendency of hydrophilic opioids to ascent towards brainstem where they can inhibit resp center
resp depression is more common with (6)
high opioid doses
co administered sedatives
low lipid solubility
advanced age
opioid naivety
increased ITP
urinary retention from neuraxial opioids MOA
inhibition of sacral PSNS tone aka SNS tone is winning
n/v from neuraxial opioids MOA
caused by activation of opioid receptors in the area postrema of medulla and vestibular apparatus
transfer of opioids from epidural space to breast milk
minimal
which LA decreases efficacy of neuraxial opioids
2 chlorprocaine
neuraxial blocks are contraindicated if platelet count is what and coags are
platelet count <100,000
coags are 2x normal value (aPTT, PT, or bleeding time)
contraindications to neuraxial opioids include
-increase in ICP
-sepsis
-infection at puncture site
-hypovolemia
-valve lesions with fixed SV
-scoliosis, arthritis, spinal fusions, osteoporosis
-full stomach
-peripheral neuropathy (theory that patients are more susceptible to injury)
-MS
-spina bifida
ID this type of spinal needle
quincke
ID this type of spinal needle
sprotte
ID this type of spinal needle
whitacre
ID this type of spinal needle
green
ID 3 types of spinal needles
cutting tip (quincke)
pencil point (sprotte, whitacre)
rounded bevel (green)