coagulant substances and factors

Question 1

pro coagulants include

Answer 1

coagulation factors
collagen
vWF
fibrinectin

Question 2

function of collagen

Answer 2

tensile strength

Question 3

function of vWF

Answer 3

platelet adhesion

Question 4

function of fibrinectin

Answer 4

cell adhesion

Question 5

function of thrombomodulin

Answer 5

regulates naturally occurring anticoagulants

Question 6

anticoagulants include (4)

Answer 6

protein C
protein S
antithrombin
tissue pathway factor inhibitor

Question 7

function of protein C

Answer 7

degrades factor 5a and 8a

Question 8

function of protein S

Answer 8

co factor for protein C

Question 9

function of antithrombin

Answer 9

degrades factors 9a, 10a, 11a, 12a

Question 10

function of tissue pathway factor inhibitor

Answer 10

inhibits tissue factor

Question 11

fibrinolytics include

Answer 11

plasminogen
tPA
urokinase

Question 12

function of plasminogen

Answer 12

precursor to plasmin (breaks down fibrin)

Question 13

function of tPA

Answer 13

activates plasmin

Question 14

function of urokinase

Answer 14

activates plasmin

Question 15

antifibrinolytics include

Answer 15

alpha anti plasmin
plasminogen activator inhibitor

Question 16

function of antifibrinolytics

Answer 16

activates tPA, urokinase

Question 17

function of plasminogen activator inhibitor

Answer 17

inhibits plasmin

Question 18

constrictive vasoactive mediators include (3)

Answer 18

thromboxane a2
ADP
serotonin

Question 19

dilatory vasoactive mediators include

Answer 19

NO
prostacyclin

Question 20

factor 1 and site of synthesis

Answer 20

fibrinogen, liver

Question 21

factor 2 and site of synthesis

Answer 21

prothrombin, liver

Question 22

factor 3 and site of synthesis

Answer 22

tissue factor, vascular wall

Question 23

factor 4 and site of synthesis

Answer 23

calcium ions, diet

Question 24

factor 5 and site of syntehsis

Answer 24

labile factor, liver

Question 25

factor 7 and site of synthesis

Answer 25

stable factor, liver

Question 26

factor 8 and site of synthesis

Answer 26

antihemophelic factor, liver

Question 27

factor 9 and site of synthesis

Answer 27

christmas factor, liver

Question 28

factor 10 and site of synthesis

Answer 28

stuart prower factor, liver

Question 29

factor 11 and site of synthesis

Answer 29

plasma thromboplastin antecedent, liver

Question 30

factor 12 and site of synthesis

Answer 30

hageman factor, liver

Question 31

factor 13 and site of synthesis

Answer 31

fibrin stabilizing factor, liver

Question 32

mnemonic for factor names

Answer 32

foolish people try climbing long slopes after christmas some people have fallen

Question 33

function of alpha 2 antiplasmin

Answer 33

inhibits action of plasmin on fibrin

Question 34

what are the 3 steps in the contemporary coagulation cascade?

Answer 34

initiation
amplification
propagation