Neonatal Sepsis Flashcards
1
Q
What is early onset neonatal sepsis?
A
Sepsis in first 48-72 hours of life
2
Q
What are the common organisms in neonatal sepsis?
A
Group B strep E.coli Listeria Klebsiella Staph aureus
3
Q
What are risk factors for neonatal sepsis?
A
Maternal vaginal GBS colonisation Maternal sepsis Maternal temp >38 GBS sepsis in previous baby Prematurity Prolonged/early rupture of membrane
4
Q
What are features of neonatal sepsis?
A
Fever Reduced tone Poor feeding Resp distress Jaundice within 24 hours
5
Q
What are red flags for neonatal sepsis?
A
Confirmed/suspected sepsis in mother
Signs of shock
Seizures
Term baby needing ventilation
Resp distress starting >4 hours after birth
Presumed sepsis in other baby in multiple pregnancy
6
Q
How is suspected neonatal sepsis investigated?
A
FBC
CRP
Blood cultures
+/- lumbar puncture if meningitis suspected
7
Q
How is neonatal sepsis managed?
A
Benzylpenicillin + gentamicin (for 7-10 days)
Fluids/feeds
8
Q
When can you consider stopping abx in neonatal sepsis?
A
36 hours
- blood culture negative
- clinical condition is good
- CRP going down
