Mycology/Parasitology Flashcards
What bug causes Tinea versicolor?
Malassezia furfur
What does M. furfur produce? What is damaged?
acids that damage melanocytes
What is the appearance of M. furfur?
spaghetti and meatballs
Which fungi can cause endocarditis in IV drug users?
Candida
What is the most specific test for H. capsulatum? What does this detect?
latex agglutination
polysaccharide capsule
Which two groups of people can mucor and rhizopus be found?
diabetics and leukemic
What do mucor and rhizopus penetrate?
Cribriform plate
Does aspergillus have septate?
yes
Do mucor and rhizopus have septate?
no
What is the treatment for mucor and rhizopus?
amphotericin B
What type of silver stain can be used for Pneumocystis?
Methamine silver
Two drugs for pneumocystis?
TMP/SMX
Pentamadine
How many nuclei are in E. histolytica?
up to four
Drug for C. parvum?
Nitazoxanide
Two drugs for toxo?
Sulfadiazine
pyrimethamine
Which bug carries African Sleeping Sickness?
Tsetse fly
Two drugs for T. brucei?
Suramin and melosoprol
When is suramin used for T. brucei?
blood borne
When is melosoprol used for T. bruce?
enters CNS
What is pork tapeworm?
Taenia solium
What is beef tapeworm?
Taenia saginata
What is dog tapeworm?
Echinococcus granulosum
What is fish tapeworm?
Diphyllobothrium latum
What is the lung fluke?
Paragmonius westermani
Which species causes cerebral malaria?
falciparum
Anti-malarial drug therapy begins with what drug?
Chloroquine
What is the MOA of chloroquine?
blocks heme polymerase
Two drugs for chloroquine malaria?
mefloquine
atovoquone/proguanil
Drug for life threatening malaria?
quinidine
Check for what before administering quinidine?
G6PDase Deficiency
Ixodes tick transmits which two diseases?
Babesia
B. burgdoferi
Two drugs for babesia?
Atovaquone and azithromycin
What organism causes Chagas Disease?
T. cruzi
Which insect transmits Chagas?
Reduviid
Which two drugs for Chagas?
Benznidazole or Nifurtimox
What are the three drugs for Leishmania dononavi?
Spiking fevers
hepatosplenomegaly
pancytopenia
Two drugs for Leishmania dononavi?
Ampho B
sodium stibogluconate
Two drugs for E. vermicularis?
Bendazoles or pyrantel pamoate
Diethylcarbamazine treats which two bugs?
Loa Loa
W. bancrofti
W. bancrofti causes which disease?
elephantiasis
Which bug causes river blindness?
Onchocerca volvulus
Drug for river blindness?
Ivermectin
Which three nematodes are ingested?
Enterobius
Ascaris
Toxocara
What organism causes visceral larval migrans?
Toxocara canis
Which three nematodes gain access through cutaneous routes?
Strongyloides
Ancyclostoma
Necator
Which three nematodes gain access through a bite?
Loa Loa
Onchocerca volvulus
W. bancrofti
What are the three tapeworms?
T. solium
D. latum
E. granulosus
Drug for T. solium?
Praziquantel
Drug for neurocysticrcosis?
Albendazole
Drug for D. latum?
Praziquantel
Drug for E. granulosus?
Albendazole
Drug for flukes?
praziquantel
What are the two flukes?
schistosoma and clonorchis
What disease of C. sinesis associated with?
cholangiocarcinoma
What two organs can Schistosoma form granulomas?
liver and spleen
Which two bugs could causes a microcytic anemia?
Necatur
Ancyclostoma
Which two bugs could cause portal HTN?
Schistosoma mansoni
Schistosoma japonicum
Do dimorphic grow at mold in heat or cold?
mold = cold
Do dimorphic grow as yeast in heat or cold?
heat = yeast
Is Histoplasma smaller or larger than RBCs?
smaller
What is the environmental form of Histo?
maro-conidia
Which dimorphic yeast can cause meningitis?
Coccidio
Is a Spherule larger than smaller than RBCs?
larger
Which dimorphic yeast can cause Erythema Nodosum?
coccidio
Which dimorphic yeast can cause Arthralgias?
coccidio
What are the two drugs for M. furfur?
miconazole
selenium sulfide
What are the five dimorphic yeast?
Blasta
Histo
Paracoccidio
Coccidio
Sporotrix
Which mold can form a pseudocyst?
candida
Barrel Shaped Arthroconidia corresponds to what yeast?
Coccidio
Allergic Bronchopulmonary Aspergillosis occurs in individuals with what two conditions?
asthma
CF
What two things may APBA cause?
bronchiectasis
eosinophilia
Which mold is notorious for infecting neutropenic patients?
Aspergillosis
Does C. neoformans hematogenously or lymphatically reach the brain?
hematogenously
Which species of yeast forms ‘ribbon-like’ hyphae?
Mucor
Muciramine or methanamine for C. neoformans?
Muciramine
Muciramine or methanamine for P. jirovecii?
methanamine
What two drugs can be used ONLY for prophylaxis of P. jirovecii?
Dapsine and Atovaquone
What is the ‘shape’ of S. schenkii?
‘cigar’
Which species of yeast can grow from an old TB site?
aspergillus
Where does Mucor proliferate?
blood vessel wall
What structure of giardia is in the stool?
cyst
Which parasite can produce bloody diarrhea?
E. histolytica
Which parasite can produce a liver abscess?
E. histolytica
Which parasite can have RBCs in the cytoplasm?
E. histolytica
Which intestinal wall layer does E. histolytica invade?
submucosa
Which two substances can be used to screen for Cryptosporidium?
auramine or rhodamine
What is the lung fluke called?
Paragmonius westermani
What is the triad of congenital T. gondi?
chorioretinitis
hydrocephalus
intracranial calcifications
What structure would be seen on biopsy of T. gondii?
tachyzoite
Which three organs does F. falciparum infect?
Brain
Lung
Kidney
Which nematode can mimmic peptic ulcer disease?
S. stercoralis
What does O. volvulus do to the skin?
black skin
Which bug causes Visceral Larval Migrans?
Toxocara canis
Which three nematodes can infect a person via consumption?
Enterobius
Ascaris
Toxocara
Which three nematodes can infect a person via direct contact?
Strongyloides
Ancyclostoma
Necatur
Which three nematodes can infect a person via a bite?
Loa loa
O. volvulus
W. bancrofti
How does paragmonius gain access to the body?
crustaceans
Which parasite can cause Granulomatous Encephalitis?
Acanthomoeba