Behavioral Science Flashcards
What is the purpose of a cross-sectional study?
to collect data from a group of people at a particular point in time
What does a cross-sectional study assess?
frequency of disease
What does a cross-sectional study report?
prevalence
What is the purpose of a case control study?
compares a group of people with a disease to a group of people w/o the disease
What does a case control study report?
odds ratio
What is the function of a cohort study?
compares a group of people with an exposure to a group of people w/o an exposure
What does a cohort report?
relative risk
What is the function of a Phase One study?
is it safe
What is the function of a Phase Two study?
Does it work
What is the function of a Phase Three study?
does the drug work better than the current gold standard
What is the function of a Phase Four study?
long term safety
What is the equation for sensitivity?
TP/ TP + FN
What is the equation for specificity?
TN / TN + FP
What is the equation for Positive Predictive Value?
TP/TP + FP
What is the equation for Negative Predictive Value?
TN/TN + FN
What two things does Positive Predictive Value correlate with?
prevalence or pre-test probability
What does NPV inversely correlate with?
prevalence
If there is less overlap between to normal distributions, is the test more or less sensitive/specific?
more sensitive and specific
If there is more overlap between to normal distributions, is the test more or less sensitive/specific?
less sensitive and specific
What is a Type One error?
seeing a difference when there is no difference
What is a Type Two error?
not seeing a difference when there is one
Does alpha correspond to Type One of Type Two?
one
Does beta correspond to Type One of Type Two?
two
What is the equation for power?
1- beta
What is another name for reliable?
precise
What is the equation for odds ratio?
AD/BC
What is the equation for Relative Risk?
[A/(A+B)]/C/(C+D)]
What does Relative Risk measure?
risk of developing disease in exposed group to unexposed group
What is the equation for Attributable Risk?
(A/A+B) - (C/C+D)
What is the equation for NNT?
1/ARR
What is the equation for Number Needed to Harm?
1/AR
What is External Validity?
extent to which a study is applicable to a population other than the study
What is Hawthorne Bias?
subjects change behavior because they know they are being studied
What is Berkson Bias?
a study only looks at inpatients
What is Recall Bias?
awareness of disease alters recall
What is procedure bias?
subjects in treatment groups are not treated the same
What is Observer-Expectant bias?
observer expects a study will work so they document that it works
What is another name for Observer Expectant Bias?
Pygmalion effect
What is Confounding Bias?
when a factor is related to both exposure and outcome
What is lead-time bias?
early detection is confused with increased survival
One standard deviation captures what percentage of the population?
68%
Two standard deviation captures what percentage of the population?
95%
Thre standard deviation captures what percentage of the population?
99.7%
What is the order of mean, median and mode for a positive skew?
mean > median > mode
What is the order of mean, median and mode for a negative skew?
mean
What does a meta-analysis increase?
statistical power
What is the Z-score for 99th percentile?
2.58
What does a t-test look for?
difference in means between two groups
What does a ANOVA look for?
differences between means of 3 or more groups
What does Tertiary prevention do?
treat
What is beneficence?
act in patients best interest
What is nonmaleficence?
do no harm
What does APGAR stand for?
Appearance
Pulse
Grimace
Activity
Respiration
Low birth weight is below what value?
How old does a social smile develop?
two months
How old does stranger anxiety develop?
6 months
How old does separation anxiety develop?
9 months
When should Moro reflex disappear?
three months
When should Rooting reflex disappear?
four months
When should Palmer reflex disappear?
six months
When should Babinski reflex disappear?
twelve months
Do elderly have more or less REM sleep?
less
Do elderly have more or less Slow Wave sleep?
less
What is presbycusis?
high-frequency hearing loss
What gets destroyed during Presbycusis?
hair cells
Where are the hair cells destroyed during Presbycusis?
cochlear base