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Jason's Locomotor > Mycology > Flashcards

Mycology Flashcards

1
Q

Fungi are eukaryotic or prokaryotic? chlorophyll?

A

Eukaryotic

No cholorphyll

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2
Q

What are unicellular fungi? aerobic?reproduction? agar?

A

Yeasts
Facultative Aerobes
budding
colonies

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3
Q

What are filamentous fungi? aerobic?reproduction? agar?

A

moulds
aerobes
asexual spores/conidia
mycelia on agar

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4
Q

what are dimorphic fungi?

A

switch between unicellular and filamentous forms

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5
Q

which fungi best adapted to grow in humans?

A

dimorphic fungi

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6
Q

what are dermatophytes?

A

grow on skin, not invasive

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7
Q

what are opportunists?

A

biggest problem in med for immunocompromised

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8
Q

most famous dermatophyte?

A

Tinea

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9
Q

Mycetoma or maduromycosis is unique because?

A

Can be caused by BOTH:

  1. Bacteria: Nocardia
  2. Fungal: Madurella
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10
Q

Candidiasis/Thrush : 3 kinds:

A

mucocutaneous
chronic mucocutaneous
systemic (AIDS, neonates, septic)

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11
Q

what do you find near river red gums?

A

C. gattii Cryptococcosis

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12
Q

Cryptococcosis cause 2 diseases:

A

pulmonary infection

meningitis

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13
Q

2 examples of Cryptococcosis?

A

C. neoformans

C. gattii

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14
Q

Aspergillosis can cause 3 things:

A
  1. Saprophytic
  2. allergic
  3. systemic:
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15
Q

Which Aspergillosis is worst kind?

A

systemic

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16
Q

Aspergillosis likes to infect what areas of body?

A

pre-existing cavities (can look like tumour)

17
Q

Can you detect fungal antigen?

A

Yes, the capsules

Latex agglutination

18
Q

Fungal detection today uses?

A

Mass Spec

19
Q

4 systemic antifungals:

A
  1. polyenes
  2. triazoles
  3. echinocandins
  4. 5-flurocytosine (oldest)
20
Q

2 topical anti-fungals:

A
  1. polyenes

2. imidazoles

21
Q

What are the two main targets of antifungals?

A
  1. ergosterol in membrane (polyenes, triazoles)

2. nucleic acids (5-flurocytosine)

22
Q

can you inject amphotericin B?

A

Nope. deadly.

23
Q

Treatment for Candida?

A

fluconazole
amphotericin B
caspofungin

24
Q

Treatment for cryptococcus?

A

amphtericin B + 5 flurocytosine

25
Q

Treatment for aspergillus?

A

voriconazole; amphotericin B

26
Q

Treatment for dimorphic fungi?

A

amphotericin B

27
Q

Treatment for dermatophytosis? 3 topical?

A
  1. terbinafine
  2. clotrimazole
  3. amorolfine
28
Q

Treatment for dermatophytosis? 3 systemic?

A
  1. terbinafine (only if widely disseminated)
  2. fluconazole
  3. griseofulvin

Jason's Locomotor (36 decks)

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