Exercise: Muscle, fuels, fatigue Flashcards
more mitochondria in muscle good?
yes, more glucose disposal in response to insulin
Type1 fibres stain what colour after acidic?
dark
Type 2 fibres stain what colour after basic?
dark
MHC in muscle fiber immunoblotting stands for?
myosin heavy chain
which muscle fiber types have most mitochondria?
Type 1 >IIa> IIx
order of muscle fiber recruitment as more force needed?
Type I then IIa then IIx
Which fiber type has influence on DM2?
Type 2
Rate of muscle decline in disuse greatest when?
0-10 days
what is the protein synthesis and ribosome genesis molecule in the hypertrophy pathway called?
mTOR
what is Foxo?
involved in protein degradation pathway for muscle atrophy
Mitochondrial adaptation to exercise?
- more mitochondria
- less lactate and CHO use
- more fat oxidation
- more endurance
- better insulin action
lactate is a biomarker used for?
seeing if there is increased mitochondrial density
glycolysis and creatine phosphate is what kind of ATP generation?
substrate level phosphorylation
What is mTOR?
the protein synthesis and ribosome genesis molecule in the hypertrophy pathway
molecule involved in protein degradation pathway for muscle atrophy?
Foxo
ATP from lipids of proteins called?
exidative phosphorylation
Power is?
how fast can you generate ATP?
Capacity is?
how long and much ATP can be generated to last?
what are fast sources of ATP?
Creatine phosphate
glycolysis
what are slower but more capacitative sources of ATP?
CHO
FFA
Fuels for sprinting predominantly?
Creatine Phosphate
Glycolysis
fuels for endurance? most to least
muscle glycogen
FFA = plasma glucose
other fat sources
what % intensity do you use mostly fats and glucose to maintain?
50-60%
female who exercises has more what oxidation?
fat oxidation
broad defenition of fatigue?
reduction in force and power generating capacity
task specific definition of fatigue?
inability to maintain required or expected force of power output
caffeine and amphetamines changes fatigue how?
changes perception of fatigue and pain
muscle feedback to brain and motivation?
metabolic feedback from muscles
what ingestion increases exercise capacity?
CHO ingestion
