Exercise: Muscle, fuels, fatigue Flashcards
more mitochondria in muscle good?
yes, more glucose disposal in response to insulin
Type1 fibres stain what colour after acidic?
dark
Type 2 fibres stain what colour after basic?
dark
MHC in muscle fiber immunoblotting stands for?
myosin heavy chain
which muscle fiber types have most mitochondria?
Type 1 >IIa> IIx
order of muscle fiber recruitment as more force needed?
Type I then IIa then IIx
Which fiber type has influence on DM2?
Type 2
Rate of muscle decline in disuse greatest when?
0-10 days
what is the protein synthesis and ribosome genesis molecule in the hypertrophy pathway called?
mTOR
what is Foxo?
involved in protein degradation pathway for muscle atrophy
Mitochondrial adaptation to exercise?
- more mitochondria
- less lactate and CHO use
- more fat oxidation
- more endurance
- better insulin action
lactate is a biomarker used for?
seeing if there is increased mitochondrial density
glycolysis and creatine phosphate is what kind of ATP generation?
substrate level phosphorylation
What is mTOR?
the protein synthesis and ribosome genesis molecule in the hypertrophy pathway
molecule involved in protein degradation pathway for muscle atrophy?
Foxo