Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Jason's Locomotor > Exercise - Drug Interactions > Flashcards

Exercise - Drug Interactions Flashcards

1
Q

exercise and drugs: what changes with blood flow?

A

redistribution, more to muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

exercise and drugs: what changes with hydration?

A

decreased or variable

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

exercise and drugs: what changes with breathing?

A

increased resp rate and tial volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

exercise and drugs: what changes with stomach?

A

decrease gastric emptying

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

exercise and drugs: what changes with intestines?

A

decreased intestinal transit time via increasing intestinal motility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

exercise and drugs: what changes with plasma?

A

loss into tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

exercise and drugs: what changes with skin?

A

vasodilation: increased flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

exercise and drugs: what changes with liver?

A

decreased hepatic flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

exercise and drugs: what changes with kidneys?

A

decreased renal blood flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

exercise and glucose control?

A

may be dysregulated due to synergy with insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

how do you get exercise-induced hypoglycaemia? 3 reasons:

A
  1. accelerated insulin absorption from injection site
  2. enhancement of insulin via exerise
  3. lack of decline in insulin secretion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

how do you get exercise-induced hyperglycaemia? 2 reasons:

A
  1. too much carb supplementation

2. too large reduction in insulin dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

how would exercise change transdermal GTN?

A

increase blood flow and temp to skin, increased bioavailability of GTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

how would exercise change transdermal GTN negatively?

A

excessive hypotension and divert coronary blood flow esp in hot enclosed environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

salbutamol is B2 or B1?

A

B2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

salbutamol and exercise? good? bad?

A

with increased resp rate, increased plasma levels,

good: minimize asthma from exercise
bad: may need more frequent dosing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

warfarin and exercise decreases? how?

A

INR via:
increased binding of warfarin to albumin
increased risk of thrombosis

18
Q

digoxin and exercise wrt plasma and muscle level?

A

less in plasma

more in muscle

19
Q

digoxin and exercise wrt plasma and muscle level implications?

A

more bound to muscle and less in plasma means reduced efficacy to affect heart contractility and control rate

20
Q

B-blockers and exercise: how is propranolol and atenolol cleared?

A

propranolol: via hepatic (decreased in exercise)
atenolol: via renal (decrease in exercise)

21
Q

B-blockers and exercise implications of increased plasma levels?

A

bronchoconstriction and fatigue

22
Q

Anti-doping rules wrt use?

A

use or attempted use of prohibited substance or method

23
Q

2 out of the following 3 conditions met for subtance/metho to be prohibited?

A
  1. enhance sport performance
  2. risk to health
  3. if agency says it violates spirit of sport
24
Q

what is therapeutic use exemptions?

A
  1. if have medical condition
  2. prior approval
  3. makes sport fairer
  4. declared in emergncy
25
Q

2 main uses of drugs in sport?

A
  1. hide use of other drugs

2. improve performance

26
Q

thiazide and amiloride use in sport advantage?

A

weight loss

dilute urine

27
Q

disadvantages of diuretics in sport?

A

dehydration

hypokalaemia

28
Q

B1 found in what tissues?

A

cardiac pacemaker
cardiac muscle
adipose

29
Q

B2 found in what tissues?

A

airway smooth muscle
blood vessel: skeletal and skin
skeletal growth
liver

30
Q

Why use B1 antagonists in sport?

A

relaxants
reduce heart rate
steady hands in precision sports

31
Q

B1 antagonists are banned in what sports?

A

archery/shooting
skiing
billiards, bridge

32
Q

B2 agonist use in sport?

A

systemic admin:

  1. anabolic for muscles
  2. catabolic for body fat
33
Q

adverse effects of B2 agonists?

A

tachycardia via B1 adrenoceptors

muscle tremor via B2 receptors

34
Q

B2 agonist status in sport?

A

only via inhalation

No TUE for salbutamol

35
Q

how can glucocorticoids offer sport advantage? disadvantage?

A

anti-inflammatory can mask pain

can cause damage before full recovery

36
Q

what is stanozolol?

A

synthetic anabolic steroid

37
Q

what glucocorticoids status in sport? without TUE?

A

banned systemic admin

No TUE: topical and inhalation

38
Q

glucocorticoids intraarticular injection TUE?

A

needs abbreviated TUE

39
Q

Growth Hormone in sport advantage?

A

reduce fat
more muscle
more bone density
banned

40
Q

what is lipotropin?

A

modified Growth Hormone to only have catabolic effect of increased lipolysis

41
Q

what does WADA status S.0 mean?

A

any substance not on the list or no human approval for use is banned

Jason's Locomotor (36 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions