Muscular System (Wray) Flashcards
Homeostasis: definition
relies on stimulus/response system
Homeostasis Levels
- pH: 7.35 - 7.45
- Temp: 37 C +- 0.5 C
- Blood glucose: 90 - 100 mg/dL
- Ca: 8.5 - 11 mg/dL
Homeostasis: Set Point
stimulates response system if goes beyond the “ok” range
Homeostasis: Control center
Receives messages from the receptor –> Interprets & analyzes –> Sends message to effector
- CNS
- endocrine system
Homeostasis: input
message sent from the receptor to the control center
- Chemical (hormone)
- Electrical (nerve impulses)
Homeostasis: effectors
- cells/tissue/organs that receive messages from control center to reestablish homeostasis
- Also creates messages
Homeostasis: effects
Changes observed in effector as a result of output
Muscular System Function
- Production of movement
- Maintaing posture
- Stabilization of joints
- Heat generation
Type of Muscles Cells
- Skeletal 2. Smooth 3. Cardiac
Skeletal Muscle (Organ) Contains (5):
- Blood supply
- Nerves
- Connective Tissue
- Attachment (direct or indirect)
- Skeletal muscle fiber
Skeletal muscle: fibers
Striated: light/dark pattern
- many fibers present
Skeletal muscle: movement
Voluntary
- could be involuntarily activated by reflex
Skeletal muscle: Connection
Connected to bones via tendons
Skeletal muscle: Nucleus
multi-nucleated
- Many muscle fibers are very long (up to 24 inches for some)
Smooth muscle
No striation
Smooth muscle: movement
Involuntary movement
Smooth muscle: Found in
- Stomach, Intestines
- Bladder
- Respiratory passage
* Movement is slow and sustained (food moves through your digestive system)
Cardiac muscle
- Found only in the heart
- Striated muscle
Cardiac muscle: movement
Involuntary movement
Cardiac muscle: Intercalated discs
- Desmosomes: proteins that connect two muscle cells together
- Provide strength for repetitive motion
Homeostasis: Sensor Controller
- Sensor and control center are the same thing
- Lack input
Skeletal muscle: Microscopic Anatomy
Sarcomere:
- Myosin- thick filament
- Actin- thin filaments
Homeostasis: Sensor
monitors?
Homeostasis: Output
messages sent from the control center to the effector cells/tissue/organ
Skeletal Muscle: Striation 1
- Dark (A band)
- Thick & thin filaments
- dark appearance: combination of 2 proteins
Skeletal Muscle: Striation 2
- Light (I band)
- Only thin filament
- Light appearance: only 1 protein
Homeostasis: Ca in the blood (7 steps)
- Set points: 8.5 mg/dL
- Stimulus: Ca levels drop below 8.5 mg/dL
- Sensor/receptor: Parathyroid glands
- Control Center: Endocrine System
PTH hormone - Effectors: a. kidney b. osteoclasts
- Effects:
a. kidney (absorbs calcium from urine)
b. osteoclasts (breaks down bone to release Ca into the blood) - Final Response: Calcium levels rise back to 8.5 mg/dL
Homeostasis: Negative Feedback Loop
- Prevents the levels from going too extreme in the other direction
- Makes homeostasis a self-regulating system
Sarcomere
structure present inside the muscle cell
- made of thick filament (myosin)
- & thin filament (actin)
Striation
- Light/dark pattern
- A-band (dark)
- I bank (light)
A-band
- dark (because of 2 proteins)
- thick & thin filaments
I-band
- light (only 1 protein)
- only actin is present
- amount of actin that is NOT overlapped with
myosin
Contraction of skeletal muscle
- requires nerve impulse
- axon terminal connected to sarcolemma of muscle
ACh (acetylcholine)
- originates from axonterminal of neuron
- released into neurotransmitter junction of muscle fiber
- Causes opening of Na+/K+ channels
Neuromuscular junction
- Space between nerve axon terminal and muscle fiber
Na+/K+ channels
- Located on surface of muscle fiber
–> creates action potential
–> release of Ca2+ from ER
–> contraction of individual sarcomere (muscle
contraction
- Action potential
- Changes voltage of cells
Calcium
Ion that causes muscle contraction
Process of muscle contraction
- Nerve impulse
- ACh released from neuron
- Causes opening of Na/K channels
- Presence of Na/K causes ER to release Ca
- Ca causes power stroke of actin –> muscle contraction
- I band (light area) gets smaller
Whole muscle contraction
- Frequency of muscle stimulation (complete
tetanus) - Changing the number of muscle cells activated
- Complete tetanus
- Increased nerve activity
- Numerous stimulus without sign of relaxation
- Ex: holding a bag for a long time - Twitch
- Single stimulus
- Ex: muscle twitch
-
- Numerous stimulus without sign of relaxation
Changing the number of muscle cells activated
- Increase muscle activity
Lighter objects contract fewer muscle cells
Aerobic respiration
- Produces 32 ATP per glucose
- Presence of oxygen
Anaerobic respiration
- Produces only 2 ATP per glucose
- Absence of oxygen
- Lactic acid is produced
Mitochondria count/muscle performance
- Low ATP production –> lack of activity –> low mitochondria
- High ATP production –> high activity –> high mitochondria
Lactic acid
- Builds due to inability of respiratory system to keep up with O2 demand
- glucose –> lactic acid + Low # ATP
Muscle fatigue
when enough O2 is present to muscles, lactic acid will be recycled to be used for aerobic respiration –> muscle fatigue goes away
Exercise/muscles
- Use it or lose it
- Types:
- Aerobic/endurance
- Resistance
Aerobic/Endurance Exercise:
Muscle Created
- Strong, flexible muscle
- No increase in muscle size
Aerobic Exercise: Reason
- Higher blood supplies
- More mitochondria
Benefits:
*Heart
*Neuron/muscle coordination
*Faster metabolism (breakdown of glucose)
Anaerobic Exercise: Muscle Created
Strong, bulky
Anaerobic Exercise: Reason
Muscle cells are enlarged