Muscular system Flashcards

1
Q

Explain the location, function and description of skeletal muscle.

A
  • Location= Attached to bone
  • Function= Voluntary movement
  • Description= Striated, multinucleate (more than one nucleus)
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2
Q

Explain the location, function and description of cardiac muscle.

A
  • Location= Walls of the heart
  • Function= In-voluntary control, auto-rhythmic
  • Description= Striated, uninucleate cells interlock at intercalated discs, single nucleus
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3
Q

Explain the location, function and description of smooth muscles.

A
  • Location= Walls of hollow organs
  • Function= Involuntary, auto rhythmic, propels substances along internal passageways.
  • Description= non-striated, cells arrange in a sheet structure, single nucleated
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4
Q

What are the functions of muscle?

A
  • Movement
  • Posture
  • Regulating organ volume
  • Moving substances in the body= Cardiac muscle (heart), smooth muscle (peristalsis), skeletal muscle (lymph / blood)
  • Heat production
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5
Q

What are the different characteristics of muscle?

A
  • Excitability= ability to respond to a stimulus
  • Contractability= ability to contract when stimulated
  • Extensibility= ability to be stretched/ extended
  • Elasticity= ability to return to its original form after being stretched
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6
Q

When does movement occur?

A
  • When a muscle contract.
  • Movement results from several muscles working together
  • Most skeletal muscles are arranged in opposing pairs
    = Antagonistic Pairs
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7
Q

Muscles are arranged in opposing pairs, what are these called?

A
  • Antagonistic pairs.
  • Agonist= contracts to cause an action
  • Antagonist= stretches and yields to action of the agonist
  • Synergist= contracts to stabilise intermediate joints
  • Fixator= stabilises origin of agonist
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8
Q

What are muscle made up of?

A
  • Bundles of muscle fibres called fascicles. These muscles and fibres are held together by sheets of connective tissue.
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9
Q

What are the sheets of connective tissue found in muscle?

A
  • Epimysium= surrounds whole muscle
  • Perimysium= surrounds bundles of fibres (fascicles).
  • Endomysium= surrounds individual muscle fibres
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10
Q

What are the different contractile proteins?

A
  • Actin and myosin are the contractile proteins.
  • Troponin and tropomyosin are contraction inhibiting proteins.
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11
Q

What is ATP?

A
  • Produces energy for muscles.
  • It is produced through different metabolic pathways: Creatine phosphate, anaerobic respiration and aerobic respiration.
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12
Q

What does anaerobic respiration do?

A
  • Provides ATP for short, moderate durations of activity (60 secs or slightly more). It does not require O2 and has two stages: Glycolysis and lactic acid formation.
  • So, breakdown of glucose into pyruvic acid (through glycolysis). It produces 2 ATP molecules per breakdown of glucose molecule. Pyruvate is then converted to lactic acid in absence of O2.
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13
Q

What does creatine phosphate do?

A
  • Provides ATP for first few seconds of high intensity activity.
  • Creatine phosphate donates a phosphate group to ADP from ATP, it is catalysed by the enzyme creatine.
  • The reaction= creatine phosphate + ADP= creatine + ATP
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14
Q

What does aerobic respiration do?

A
  • Provides ATP for prolonged activities: several mins- hours.
  • It requires O2 and has three stages: glycolysis, kreb’s cycle, oxidative phosphorylation.
  • Mechanism: Involves Krebs cycle, oxidation of glucose, fatty acids and amino acids in presence of oxygen. Produces 32 ATP molecules per glucose molecule.
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15
Q

What are some physiological changes during exercise?

A
  • Increase in CO2 and lactic acid
  • Increase in muscle movement
  • Increase return of blood flow to the heart
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16
Q

What receptors detect physiological changes?

A
  • Chemoreceptors detect co2
  • Proprioceptors detect muscle movement
  • Baroreceptors detect blood flow to the heart
17
Q

What are the outcomes of these physiological changes?

A
  • Increase ventilation and cardiac output
  • Vasodilation, vasoconstriction and increased sweating etc.
18
Q

What changes do skeletal muscles go through as we age?

A
  • Sarcopenia= loss of muscle mass and strength.
  • Reduced muscle repair and regeneration
  • Neuromuscular changes and motor neuron loss
  • Increased muscle stiffness
19
Q

What are muscle fibres made up of?

A

= Myofibrils.
Myofibrils are divided lengthways into sarcomeres, which have the myofilaments actin and myosin.

20
Q

What happens during muscle attachment?

A
  • One end of the muscle is attached to a structure (usually bone) that remains stationary. This is known as the Origin of the muscle
  • The opposite end of the muscle that is moved by the contraction is known as the Insertion
21
Q

What are muscle fibres made up of?

A
  • Myofibrils
  • Each myofibril is made up of the contractile proteins Actin and Myosin to make Myofilaments.
  • It is the overlapping of the thin actin and thick myosin filaments that give muscle its striated (striped) appearance