Liver, gall bladder and pancreas Flashcards
Liver=
- Detoxification of metabolic wast
- Destruction of spent RBC
- Secretion of bile
- Synthesis of plasma proteins
- Processing and storage of nutrients absorbed from gut tube
- storage of fat soluble vitamins
Liver lobule=
The liver has two lobes — the right and the left. Each lobe is made up of thousands of hexagonally-shaped lobules.
The lobules are separated by connective tissue with portal tracts.
There are portal triads at the corners of lobules
What are portal triads?
Segments of the portal vein, hepatic artery, and bile ducts.
What is the space of disse?
is a space between a hepatocyte, and a sinusoid in the liver. It contains the blood plasma.
Gall bladder=
- Muscular sac, sores and concentrates bile 5-10x
-Tall columnar epithelium with brush border - Has lymph/ blood vessels in submucosa to transport H20 away
Bile=
produced by your liver. It helps your body break down fats in the foods you eat.
- has bile salts that emulsify fats
- the bile pigments are broken down into stercobilin
- has cholesterol, triglycerides, phospholipids and electrolytes
Pancreas=
Your pancreas is a large gland in the back of your stomach. It releases enzymes to help with digestion and hormones to regulate blood sugar.
- The exocrine component forms 80% of the gland
- It secretes alkaline fluid which is rich in enzymes
- neutralises acid chyme from stomach
- trypsin/ chymotrypsin is secreted in inactive form which prevents auto-digestion
- activated in the duodenum
Explain the control of bile and pancreatic secretion=
The presence of acidic chyme in intestine stimulates production of intestinal juice.
- secretion stimulates liver cells to release bile & pancreatic secretion
- CCK stimulates gallbladder contraction & pancreatic secretion