Muscles 2 Flashcards

1
Q

What increases during aerobic endurance training?

A

Fatigue resistance
Blood capillaries

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2
Q

What increases in anaerobic endurance training?

A

Myofibril size (more myofilaments)
Diameter of muscle fibre

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3
Q

Where is the energy provided from in first 2 mins of exercise?

A

Stored energy
Anaerobic glycolysis

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4
Q

What do muscle cells have a reserve of?

A

ATP
Phosphocreatine

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5
Q

The build up of what stimulates metabolic pathways in energy release?

A

ADP
AMP
Phosphate

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6
Q

What happens to creatine at rest?

A

Recycled into phosphocreatine in mitochondria

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7
Q

Glycogenesis of glucose produces …

A

Glucose 1 phosphate

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8
Q

At what state does glucose enter glycolysis?

A

Glucose 6 phosphate

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9
Q

What takes up glucose from blood?

A

GLUT4

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10
Q

Why do muscles fatigue?

A

H+ from lactic acid lowers the cells pH
Lactic acid accumulates from pyruvate

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11
Q

Advantage of anaerobic conditions

A

Produces ATP in the absence of 02

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12
Q

Disadvantage of anaerobic conditions

A

ATP yield is low and toxic products are generated

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13
Q

What are the results of anaerobic conditions?

A

2 ATP
Lactic acid

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14
Q

What do aerobic conditions produce?

A

38 molecules of ATP

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15
Q

What happens when tissue oxygen delivery increases in aerobic energy release?

A

Oxidative phosphorylation energy production is stimulated

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16
Q

What feeds oxidative phosphorylation during aerobic energy release?

A

Lactate is converted back to pyruvate

17
Q

What releases lactate into circulation?

A

Type IIx fibres

18
Q

What happens during extended periods of aerobic energy release?

A

Lactate and alanine can be used by the liver to generate glucose.
Redistribution of glycogen stores.
Mobilisation of non-muscle lipids, increasing in circulating fatty acids taken up by muscle.
Breakdown of triacylglycerol stored in muscles.

19
Q

Define muscle fatigue?

A

Inability to maintain a desired power output.
Decline in force and velocity of muscle shortening

20
Q

Define central fatigue

A

Deficient drive of motor cortical output

21
Q

Define peripheral fatigue

A

Decrease in contractile strength of muscle fibres

22
Q

Define high-frequency fatigue

A

Alteration in cell Na/K balance, particularly in type II fibres

23
Q

Define low-frequency fatigue

A

Reduced release of Ca2+ from sarcoplasmic reticulum, particularly type I fibres

24
Q

Define ATP depletion

A

Intense stimulation causing large drops in ATP near cross bridge formation and ATPases

25
What does lactic acid build up cause?
Cellular acidification
26
What is glycogen depletion?
Lack of glycogen leads to lack of glucose 'Hitting a wall'