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Phys, pharm > Epithelia > Flashcards

Epithelia Flashcards

1
Q

How many cell layers do simple epithelia have?

A

A single layer of cells

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2
Q

How many cell layers do stratified epithelia have?

A

Many layers of cells

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3
Q

Appearance of simple squamous

A

Thin scales

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4
Q

Specialisation of simple squamous

A

Facilitated rapid passage of molecules

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5
Q

Appearance of simple cuboidal

A

Fat cells with nuclei in the middle of the cells

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6
Q

Function of simple cuboidal

A

Secretion and absorption of molecules via active transport

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7
Q

Appearance of simple columnar

A

With cilia (on apical side) or without cilia
Longer cells with nuclei at lower

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8
Q

Function of simple columnar

A

Absorption/secretion of molecules via active transport
Removal of respiratory particle matter
Line fallopian tubes

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9
Q

Appearance of pseudostratified columnar

A

Single cell layer with multilayer appearance
Nuclei reside at different levels
Ciliated cells interspersed with goblet cells
Basal membrane

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10
Q

Appearance of stratified squamous

A

Apical = squamous
Basal = cuboidal/columnar

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11
Q

Where do stratified squamous cells reside?

A

In areas of high abrasion
Keratinised in skin upper layers
Non keratinised in oesophagus

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12
Q

Appearance of stratified cuboidal

A

Nuclei present fat

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13
Q

Where do stratified cuboidal cells reside?

A

In glands

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14
Q

Function of stratified columnar

A

Allow tissues to stretch or contract

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15
Q

Where do stratified columnar cells reside?

A

Conjunctiva, pharynx, anus, male urethra and embryo

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16
Q

Appearance of transitional cells

A

Cells are round when relaxed
Flat when contracted

17
Q

Function of transitional cells

A

Facilitates shape change in distension without damaging epithelial lining

18
Q

Where are mucus secretions produced?

A

Mucus gland

19
Q

Where are protein secretions produced?

A

Serous gland

20
Q

Where are ductless secretions produced for?

A

The endocrine system

21
Q

Where are duct secretions produced for?

A

The exocrine system

22
Q

What cells are unicellular secretions released from?

A

Goblet cells

23
Q

What cells are multicellular secretions released from?

A

Acinar/acinus cells

24
Q

What is the function of the basement membrane?

A

Separates the epithelia from underlying connective tissue
Provides mechanical strength

25
Q

What is the basal lamina spilt into?

A

Lucida and Densa

26
Q

Where does the reticular lamina reside?

A

Under the basal lamina
Fibres anchor the basal lamina to collagen or elastin

27
Q

How to lateral cell to cell communications occur?

A

Via Gap junctions

28
Q

What filament allows for contraction?

A

Myosin filaments

29
Q

What is linked by adhesion junctions?

A

Stress bearing cytoskeleton links cells to cell via adhesion junctions

30
Q

How long does interstial self-renewal take?

A

5 days

31
Q

How long does the interfollicular epidermis take ?

A

4 weeks

32
Q

How long does renewal of lung epithelium take?

A

up to 6 months

33
Q

What does adherens junction connect?

A

Actin filament bundles in 1 cell to the next

34
Q

What do desmosomes connect?

A

Intermediate filaments (cells with high mechanical stress)

35
Q

What do hemidesmosomes connect?

A

Anchors intermediate filaments to extracellular matrix

36
Q

What do tight junctions connect?

A

Seals the gap between epithelial cells on apical surface

37
Q

What do tight junctions connect?

A

Seals the gap between epithelial cells on apical surface

38
Q

What induces formation of epithelium?

A

Switched expression of cadherins inducing mesenchymal cells (fibroblasts) to form epithelium

Phys, pharm (31 decks)

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