Muscle Histology Flashcards
Skeletal Muscle
four characteristics: voluntary, striated, not branched, and multinucleated
usually attached to one or more bones; composed of numerous skeletal muscle fibers, blood vessels, and nerves, and connective tissue sheets that surround the muscle fibers and connect muscle to bone

Myofiber (l.s)
Elongated, multinucleated,
cylindrical fiber (cell); contains
myofibrils, separated from
other fibers by layer of areolar
connective tissue; exhibits
striation

Myofiber (x.s)
Elongated, multinucleated,
cylindrical fiber (cell); contains
myofibrils, separated from
other fibers by layer of areolar
connective tissue; exhibits
striation

Nucleus (l.s) (skeletal muscle)
located on periphery of cell

Nucleus (x.s) (skeletal muscle)
located on periphery of cell

Striations: A-Band (l.s) (skeletal muscle)
Dark band in the middle of
the sarcomere; composed
of entire thick filaments
and on its lateral end
regions of overlapping thin
filaments

Striations: I-Band (l.s) (skeletal muscle)
Light band containing
thin filaments only and
connectin proteins

Endomysium (l.s)
innermost connective tissue layer; it is a delicate, areolar CT layer that surrounds and electrically insulates each muscle fiber

Endomysium (x.s)
innermost connective tissue layer; it is a delicate, areolar CT layer that surrounds and electrically insulates each muscle fiber

Perimysium (x.s)
located around the fascicles; dense irregular CT sheath of the perimysium contains extensive arrays of blood vessels and nerves that branch to supply each individual fascicle

Epimysium (x.s)
a layer of dense irregular CT that surround the whole skeletal muscle

Fascicle (x.s)
A bundle of muscle fibers
separated from other bundles
of fibers by a dense irregular
connective tissue covering

Type 1 Fibers (x.s)
Slow oxidative fibers; appear dark red because of presense of large amount of myoglobin; cells produce contractions that are slower and less powerful, however can contract over long periods of time without fatigue because ATP is supplied primarily thorugh aerobic cellular respiration.

Type 2 Fibers (x.s)
Split into fast oxidative fibers (Type IIA) and fast glycodytic fibers (Type IIB);
Fast oxidative fibers: least numerous of skeletal muscle fiber types; produce a fast, powerful contraction with ATP provided primarily through aerobic respiration; appear a lighter red than slow oxidative fibers
Fast glycolytic fibers: most prevalent skeletal muscle fiber type; provide both power and speed but can only contract for short bursts because ATP is provided primarily through anaerobic cellular respiration.

Cardiac Muscle
individual muscle cells arranged in thick bundles within the heart wall; branch and are both shorter and thicker than skeletal muscle fibers

Cardiocyte
myocytes of the heart;
Cardiomyocytes, also known as cardiac muscle cells, usually contain one elongated nucleus that lies in the centre, which is a distinguishing feature from skeletal muscle. By examining the ultrastructure, it becomes apparent that the myofibrils separate as they approach the nucleus, pass around it and re-assemble in their original pattern on the other side

Nucleus of cardiac muscle

Striations: A-bands (Cardiac muscle)
Dark band in the middle of
the sarcomere; composed
of entire thick filaments
and on its lateral end
regions of overlapping thin
filaments

Striations: I-band (Cardiac muscle)
Light band containing
thin filaments only and
connectin proteins

Intercalated discs
unique to cardiac muscle; they are composed of desmosomes and gap junctions; only one or two nuclei; junctions where individual cells are joined to adjacent muscle cells

Smooth Muscle
composed of short muscle cells that have a fusiform shape (widest at the middle of the cell and tapered at each end); single, centrally located nucleus; have both thick and thin filaments but not precisely aligned, so no visible striations or sarcomeres

Nucleus (smooth muscle)

Non-striated (smooth muscle)
What is a significant difference between the appearance of this cell compared to that of other muscles?

Endomysium (smooth muscle)
layer of areolar connective tissue that ensheathes each individual myocite
for what muscle type is this image of?

What is the tissue type of tendons?
it is composed of dense fibrous connective tissue made up primarily of collagen fibers

What is the difference between a relaxed sarcomere and fully contracted sarcomere?
