Muscle Contration Flashcards
What is the first step of the muscle contraction process
Nervous impulse arrives at the synaptic knob
Once the nerve impulse arrives at the synaptic knob ______ enters the synaptic knob which triggers the release of ________
Calcium enter the synaptic knob which triggers the release of acetylcholine
Once ACh is released from the synaptic knob it
enters the synaptic cleft and binds to receptors on the muscle cell motor end plate
Where is the muscle cell motor end plate
sarcolemma
The binding of ACh to the muscle cell motor end plate results in
depolarization of the sarcolemma
Once the sarcolemma is depolarized the impulse travels along
the sarcolemma and through the T-tubules
Impulse reaches the sarcoplasmic reticulum which causes the release of _________ which spreads ______
calcium which spreads throughout the cell
Calcium then binds to ______ on the thin myofilament
troponin
When calcium binds to troponin on the thin myofilament
tropomyosin is displaced and binding sites on actin are exposed
When does the cross bridge form
when myosin binds to actin
Sarcomeres _____ when filaments slide past one another and muscle contracts
shorten (sliding filament theory)
What are the 4 stages of cross-bridge cycling
- Attach 2. Pivot 3. Detach 4. Reset
Attach
Myosin bonds to actin
Pivot
Myosin pulls thin filament toward each other
Detach
ATP attaches to myosin and myosin head detaches