musch 1 Flashcards

1
Q

what are the 3 methods of oxygen and nutrients to tissue?

A
  1. neural
  2. mechanical
  3. hormonal mechanism
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2
Q

what does a Swan-Gantz catheter measure?

A

pulmonary wedge pressure

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3
Q

Where is CvO2 sampled from?

A

only the pulmonary artery

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4
Q

Where is the CasO2 sampled from?

A

sampled from any artery except the pulmonary artery

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5
Q

Qrv ____ Qlv

A

Qrv = Qlv (equal output)

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6
Q

HRxSVrv _____ HRxSVlv

A

HRxSVrv = HRxSVlv (equal stroke volume)

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7
Q

what is the RV?

A

volume pump (thin wall)

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8
Q

what is the LV?

A

pressure pump (thick wall)

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9
Q

is cardiac muscle voluntary or involuntary?

A

involuntary

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10
Q

are cardiac muscle cells shorter or longer than skeletal muscles cells?

A

shorter

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11
Q

do cardiac muscle cells have more or less mitochondria than skeletal muscle cells?

A

more

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12
Q

does preload have a positive or negative effect on stroke volume?

A

positive effect

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13
Q

does contractility have a positive or negative effect on stroke volume?

A

positive effect

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14
Q

does afterload have a positive or negative effect on stroke volume?

A

negative effect

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15
Q

end - diastolic volume is a measure of what?

A

preload

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16
Q

end - diastolic volume is dependent on what?

A

LVEDP and venous return

17
Q

stimulating a beta-1 receptor does what to HR?

A

increases HR

18
Q

stimulating a muscarinic receptor does what to HR?

A

decreases HR

19
Q

what is the neurotransmitter for the sympathetic nervous system?

A

norepinephrine

20
Q

what is the neurotransmitter for the parasympathetic nervous system?

A

acetylcholine

21
Q

do the pacemaker cells of the heart contract?

A

no

22
Q

effects of norepi and epi on ventricular chromotropic state

A

beta-1 receptor -> increases CAMP ->protein kinase

  1. funny channel opens: increase Na+ influx
  2. calcium channel opens: increase Ca++ influx
  3. increases the rate of depolarization
23
Q

effects of Ach on ventricular chromotropic state

A

muscarinic receptor -> increase K+ permeability and decrease Ca++ permeability -> decreases rate of depolarization

24
Q

what initially raises heart rate during exercise?

A

parasympathetic withdrawal