GI1 Flashcards

1
Q

how is the GI system regulated?

A
  • innervation
  • hormonal control
  • immune control
  • trophic effects
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2
Q

what is feeding?

A

the acquisition and ingestion of food

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3
Q

what species has the simplest GI system?

A

C. elegans

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4
Q

ezymatic digestion is the breakdown of what?

A

starches/sugars, proteins and fats

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5
Q

fermentative digestion involves what/

A

symbiotic microbes

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6
Q

bacteria in your gut can break down antioxidants in chocolate into what

A

anti-inflammatory compounds

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7
Q

what kind of digestion do carnivores have?

A

primarily enzymatic

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8
Q

what kind of digestion do omnivores have?

A

enzymatic and fermentative

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9
Q

______ ______ and ____ control are essential for GI functions

A
  • intrinsic neural

- endocrine

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10
Q

what does motility do?

A

moves food

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11
Q

what does digestion do?

A

secretion of digestive substances

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12
Q

what does absorption do?

A

transports nutrients from the lumen to the blood

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13
Q

what is delivery?

A

circulation/distribution of absorbed substances

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14
Q

how is the GI protection?

A
  • barrier function

- defense mechanism against pathogen invasion

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15
Q

what are the two parts of the extrinsic system?

A
  • nerves (PS;S)

- extrinsic hormanal

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16
Q

what are the 4 parts to intrinsic systems?

A
  • intrinsic hormonal
  • immune control
  • trophic effects
  • nerves (ENS)
17
Q

what does the “autonomy of the GI system” mean?

A

that the GI system is self-regulating

18
Q

what intrinsically regulates the GI system ?

A

enteric nervous system

-neurogenic control of both secretion and GI motility

19
Q

what are the three components to the ANS?

A

PS, S, ENS

20
Q

how is the ENS modulated?

A

inputs from the extrinsic PS and S components

21
Q

what is the submucosal plexus, what is the name of one, and where is it located?

A

-secretions and local blood flow
-Meissner’s plexus
located in the submucosal layer

22
Q

what is the myenteric plexus, what is the name of one, and where is it located?

A
  • muscle contraction and motility
  • Auerbach;s plexus
  • located between the circular and longitudinal muscles layers
23
Q

what are two properties of the ENS neurons?

A

they have collaterals and varicosities

24
Q

what is the input for chemoreceptors?

A

luminal chemical conditions

25
Q

what is the input for mechanoreceptors

A

distension within muscle layers

26
Q

what are the output targets for excitatory neurons (e.g ACh, Sustance P)

A

glands: secretion (or not)

27
Q

what are the output targets for inhibitory neurons (e.g. NO, VIP)

A

Muscle layers: contraction/relaxation

28
Q

what extrinsic components of the parasympathetic NS act on the GI?

A
  • vagus n
  • pelvic n
  • pre-ganglionic
  • stimulatory***
  • ACh (cholinergic
29
Q

what extrinsic components of the sympathetic NS act on the GI?

A
  • splanchnic n
  • primarily post-ganglionic
  • inhibitory
  • norepi (adrenergic)
30
Q

what NT does the ENS use?

A

NO and VIP

31
Q

parasympathetic neurons (stimulate/inhibit) motility?

A

stimulate

32
Q

sympathetic neurons (stimulate/inhibit) motility?

A

inhibit

33
Q

can the sympathetic NS override the PS influence on the GI tract?

A

YES

34
Q

where do the PS fibers synapse?

A

on the ENS cell bodies