fong III Flashcards

1
Q

how much cardiac output is delivered to the nephron?

A

1/5

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2
Q

what occurs at the interface between vascular and epithelial structures?

A

filtration

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3
Q

is filtration highly or lowly selective?

A

highly selective

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4
Q

what are the determinants of permeability across the glomerular filtration barrier?

A
  • size
  • charge
  • shape
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5
Q

amount filtrate/amount blood should =?

A

1

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6
Q

the filtration barrier carries what charge?

A

( - )

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7
Q

what selects for shape in during filtration?

A

endothelial cells and podocytes

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8
Q

what does SNGFR stand for?

A

single nephron glomerular filtration rate

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9
Q

what forces govern intravascular /transcellular fluid movements?

A

Starling forces

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10
Q

what pressure builds up as filtration proceeds?

A

capillary oncotic pressure

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11
Q

what are the regulators of glomerular filtration?

A
  1. hormonal
  2. autoregulation
  3. tuboglomerular feedback
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12
Q

what stimulates the renin-angiotensin-aldosterone system?

A

a drop in blood pressure

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13
Q

high tubular transport is measure by what?

A

macula densa cells

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14
Q

what are the units of clearance?

A

volume/time

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15
Q

what are the units for filtered load?

A

mass/unit time

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16
Q

t/f: your clearance will change as you change your concentration of inulin.

A

false

17
Q

what is the solution to the impracticality of inulin infusion?

A

measuring creatinine clearance

18
Q

creatinine is a normal product of what?

A

protein metabolism