MPR Study Session

Question 1

Where is CHE synthesized?

Answer 1

liver

Question 2

An increase in CHE would cause

Answer 2

nephrotic syndrome and heptaocyte recovery

Question 3

A decrease in CHE would cause

Answer 3

liver disease

Question 4

Organophosphates are what type of inhibiter?

Answer 4

suicide inhibiter, irreversibly binds to CHE

Question 5

How would you treat an exposure to organophosphates?

Answer 5

Atropine Sulfate (prevents Ach from binding to AchR)

Question 6

Where our Aspartate Transaminases produces

Answer 6

Cardiac cells, liver, and blood cells

Question 7

In infants, would you be alarmed with high levels of AST?

Answer 7

no, physiological levels increase in infants and hemolysis

Question 8

Increase ASTs would stem from

Answer 8

MI, acute hepatitis,

modern increase in liver cirrhosis

Question 9

Alanine Transaminases produced

Answer 9

skeletal muscle, liver

Question 10

Increase in ALT would cause

Answer 10

Acute hepatitis,

modern levels chl. jaundice

Question 11

Where are Alkaline Phosphates produced

Answer 11

bile duct and bone

Question 12

Increases in ALP would suspect

Answer 12

bone disease and bile duct disease

Question 13

After a high fat meal, what would increase?

Answer 13

ALP levels

Question 14

If a woman is pregnant, what levels would increase AST, ALT, or ALP?

Answer 14

ALP levels would increase

Question 15

Acid phosphate is produced where

Answer 15

majority in the prostate

Question 16

What is the tumor maker for prostate cancer?

Answer 16

PSA

Question 17

In the heart, what are the types of LDH?

Answer 17

1 and 2

Question 18

In the liver, what are the types of LDH?

Answer 18

4 and 5

Question 19

CK-BB produced where?

Answer 19

brain

Question 20

CK-MB produces in the ?

Answer 20

heart

Question 21

GGT is produced where ?

Answer 21

bile duct

Question 22

Amylase and lipase is produced

Answer 22

pancreas

Question 23

First enzyme to elevate in acute MI

Answer 23

troponin

Question 24

second enzyme to raise in acute MI

Answer 24

CK-MB

Question 25

last enzyme to elevate

Answer 25

AST

Question 26

normal allele for CHE

Answer 26

e1u

Question 27

Abnormal allele for CHE for dibucaine

Answer 27

e1a

Question 28

abnormal allele for CHE for flouride

Answer 28

e1f

Question 29

abnormal allele for CHE silent protein

Answer 29

e1s

Question 30

low levels of albumin and high levels of alpha 2 macro globulin

Answer 30

nephrotic syn

Question 31

elevated alpha fetoprotein levels

Answer 31

Down’s syn

Question 32

decreased levels of alpha fetopreotein

Answer 32

neural tube defects

Question 33

LDH1/2 are positive or negative?

Answer 33

positive near the cathode

Question 34

LDH4/5 are

Answer 34

negative near anode

Question 35

Brain>Heart >skeletal muscle charges

Answer 35

(-) to (+) on electrophoresis

Question 36

GGT breaks down

Answer 36

alcohol, drugs, used in a Toxic Screening

Question 37

Enzyme the cleaves Arachidonic Acid

Answer 37

Phospolipase A2

Question 38

Enzyme that converts Arch Acid to Thromboxane A2

Answer 38

Cylcooxygenase

Question 39

What two things prevent platelet aggregation in the vessel?

Answer 39

NO and prostacyclins

Question 40

What forms the bridge between platelets and Fibrin

Answer 40

GPB

Question 41

Collagen Type IV

Answer 41

eosinophillic likes (-) charged, collagen is (+) charged