Complement Flashcards
1
Q
Where are CR1 receptors located?
A
Macrophages, monocytes, RBCs
2
Q
What is the function of CR2?
A
CD21, co-receptor of B-Cell Receptor
3
Q
What do CR1 receptors degrade?
A
C3b and C4b in blood
4
Q
What is the common function of CR1, CR2, CR3?
A
phagocyotosis
5
Q
CR1 is responsible for removing what substance from the RBC?
A
Immune complexes (C3b and C4b)
6
Q
MAC
A
(c9)x-c8c7c6c5bc4bc2bc3b
7
Q
Chemotaxis
A
c5a, c3a, C567
8
Q
anaphaylatoxin
A
C5a>C3a>C4a
9
Q
opsonization
A
C3b
10
Q
Deficiencies in early complement components
A
lupus-like immunes complex disease
11
Q
C3 deficiencies
A
pyogenic, associated with lupus-defiencies in Factors D, I, H, Properdin
12
Q
C5-C9
A
Niesseral infections
13
Q
CI INH
A
hereditary angioedema
14
Q
Factor J
A
inhibits C1q at the site of IgG
15
Q
CI INH
A
prevents the CI esterase-C2 and C4 conterase
