Complement

Question 1

Where are CR1 receptors located?

Answer 1

Macrophages, monocytes, RBCs

Question 2

What is the function of CR2?

Answer 2

CD21, co-receptor of B-Cell Receptor

Question 3

What do CR1 receptors degrade?

Answer 3

C3b and C4b in blood

Question 4

What is the common function of CR1, CR2, CR3?

Answer 4

phagocyotosis

Question 5

CR1 is responsible for removing what substance from the RBC?

Answer 5

Immune complexes (C3b and C4b)

Question 6

MAC

Answer 6

(c9)x-c8c7c6c5bc4bc2bc3b

Question 7

Chemotaxis

Answer 7

c5a, c3a, C567

Question 8

anaphaylatoxin

Answer 8

C5a>C3a>C4a

Question 9

opsonization

Answer 9

C3b

Question 10

Deficiencies in early complement components

Answer 10

lupus-like immunes complex disease

Question 11

C3 deficiencies

Answer 11

pyogenic, associated with lupus-defiencies in Factors D, I, H, Properdin

Question 12

C5-C9

Answer 12

Niesseral infections

Question 13

CI INH

Answer 13

hereditary angioedema

Question 14

Factor J

Answer 14

inhibits C1q at the site of IgG

Question 15

CI INH

Answer 15

prevents the CI esterase-C2 and C4 conterase

Question 16

Factor I

Answer 16

inhibits C3b and C4b

Question 17

Properdin

Answer 17

stabilizes C3bBb

Question 18

Factor H or DAF

Answer 18

disassociates C3b and Bb

Question 19

CD 59 HRF

Answer 19

no C9 binding to form pore

Question 20

MASP1 MASP2

Answer 20

required for MBL pathway

Question 21

What secretes MBL?

Answer 21

liver

Question 22

What stimulates liver secretions of MBL?

Answer 22

IL-6

Question 23

Recognition unit in Classical Pathway

Answer 23

C1qrs

Question 24

Where is Mg++ required in Classical Pathway?

Answer 24

for the C3 convertase