Hematology

Question 1

What are the components of a CBC?

Answer 1

1) Hemoglobin
2) hematocrit
3) RBC
4) RBC indices
5) RDW
6) WBC
7) platelet count
8) PBS

Question 2

What is the best indicator of O2 carrying capacity in the blood?

Answer 2

Hemoglobin

Question 3

Mean Corpuscular Hb (MCH) tells you what ?

Answer 3

the average mass of Hb in an individual RBC

Question 4

Mean Corpuscular Hb concentration (MCHC) tells you what?

Answer 4

the average Hb concentration in a given volume of packed red cells

Question 5

Hematocrit tells you what?

Answer 5

of RBCs

Question 6

MCV tells you what?

Answer 6

Size of the RBCs

Question 7

Why would there be Normoblastic cells in a peripheral blood smear?

Answer 7

possibly due to hemorrhage ( remember normoblastic cells are like proerythroblasts which mean they are still nucleated and when you are losing blood more blood will also be produced )

Question 8

When looking at the CBC of an iron deficient patient, their MCV will be considered what?

Answer 8

microcytic

*Remember the mnemonic FAST ( Fe deficient, Anemia, Sideroblastic anemia, Thalassemia)

Question 9

A patient with pernicious anemia will have what type of cells (MCV wise) ?

Answer 9

Macrocytic

Remember “Big Fat Pig” ( B12 deficient, Folate Deficient and Pernicious anemia)

Question 10

Newly released RBCs from the Bone marrow are called what?

Answer 10

Reticulocytes

Question 11

Why is an ESR (erythrocyte sedimentation rate) a good test to utilize with patients with inflammation, infections and cancer?

Answer 11

ESR measures acute phase responses, the acute phase proteins bind to RBCs and elevate ESR

Question 12

Patient has decreased Hb concentration and increased central pallor (paleness) what will you call the RBCs?

Answer 12

Hypochromic

Question 13

Hyperchromic

Answer 13

increased Hb concentration

decreased central pallor

Question 14

Howell-Jolly bodies are associated with what?

Answer 14

associated with absent of spleen or non functioning spleen

Question 15

Heinz body are associated with what?

Answer 15

associated with glucose 6 phosphate dehydrogenase deficiency

Question 16

Siderocytes are associated with what?

Answer 16

iron overload ( RBCS iron granules are not bound to Hb )

Question 17

Punctuate basophilia are seen when:

Answer 17

reticulocyte ribosomes are altered and have a tendency to aggregate.

Question 18

Patient has Larger RBCs, Persistence of RNA and increased Reticulocytes what is the most likely diagnosis?

Answer 18

Polychromasia

Question 19

Which anemia will result in a decreased recticulocyte number?

Answer 19

Inadequate production Anemia

Question 20

Patient with increased RBCs, increased Hb and increased Hematocrit will most likely be diagnosed with what?

Answer 20

Polycythemia

Question 21

poikilocytosis refers to what?

Answer 21

variation in shape of the RBCs