Module 5.6 Tubular Reabsorption Flashcards
Define tubular reabsorption
the movement of solute and water from the tubules back into the plasma in the peritubular capillaries
With the exception of ________\_, all solutes are in the same concentration in the glomerular filtrate as in the plasma
With the exception of plasma proteins, all solutes are in the same concentration in the glomerular filtrate as in the plasma
Most reabsorption occurs in the _______\_and is (regulated/not regulated)
Most reabsorption occurs in the proximal tubule and is (regulated/not regulated)
Reabsorption is a highly ___\_process, with most solutes requiring the presence of a _______\_ to facilitate movement across the reabsorption barrier
Reabsorption is a highly selective process, with most solutes requiring the presence of a transport protein to facilitate movement across the reabsorption barrier
The reabsorption barrier consists of the
- _______\_,
- _______\_,
- _______\_, and
- _______\_, as shown in the following diagram.
The reabsorption barrier consists of the
- tubular epithelial cell,
- basement membrane,
- peritubular space, and
- capillary endothelial cell,
as shown in the following diagram.
![](https://s3.amazonaws.com/brainscape-prod/system/cm/304/190/914/a_image_thumb.jpg?1582955362)
Reabsorption can occur _____\_or ____\_
Reabsorption can occur passively or actively
In _____\_ reabsorption, no energy is required for reabsorption to occur
In passive reabsorption, no energy is required for reabsorption to occur
Provide an example of a solute that moves passively:
The protein metabolism waste product urea is passively reabsorbed as it freely diffuses down its concentration gradient across the tubular epithelial cell
In ____\_ reabsorption, energy is required at one or more steps in the reabsorption process
In active reabsorption, energy is required at one or more steps in the reabsorption process
Provide an example of a solute that is actively reabsorbed:
![](https://s3.amazonaws.com/brainscape-prod/system/cm/304/191/549/q_image_thumb.jpg?1582956566)
Glucose is actively reabsorbed as it is transported across the apical membrane of the tubular epithelial cell by a secondary active transport protein and then across the basolateral membrane by a facilitated diffusion carrier protein.
![](https://s3.amazonaws.com/brainscape-prod/system/cm/304/191/549/a_image_thumb.jpg?1582956558)
To be reabsorbed, a substance must pass 5 barriers in a process called?
Transepithelial transport
What are the five steps of Transepithelial Transport?
- Substance must leave the __________by crossing the _______\_ of the tubular cell
- Must pass through _______\_ from one side of the tubular cell to the other
- Must cross the _______\_of the tubular cell to enter the _______\_
- Must diffuse through the _______\_
- Must penetrate the _______\_to enter the _______\_
![](https://s3.amazonaws.com/brainscape-prod/system/cm/304/191/699/q_image_thumb.jpg?1582957028)
What are the five steps of Transepithelial Transport?
- Substance must leave the tubular fluid by crossing the luminal membrane of the tubular cell
- Must pass through cytosol from one side of the tubular cell to the other
- Must cross the basolateral membrane of the tubular cell to enter the interstitial fluid
- Must diffuse through the interstitial fluid
- Must penetrate the capillary wall to enter the blood plasma
![](https://s3.amazonaws.com/brainscape-prod/system/cm/304/191/699/a_image_thumb.jpg?1582957039)
Fill in the % for each reabsorbed substance
![](https://s3.amazonaws.com/brainscape-prod/system/cm/304/191/818/q_image_thumb.jpg?1582957483)
![](https://s3.amazonaws.com/brainscape-prod/system/cm/304/191/818/a_image_thumb.jpg?1582957503)