Module 3 Quizzes Flashcards
A pharmacy student observes a layer of clear oil on the top of what was once a uniformly dispersed emulsion. What term describes what has happened?
breaking
Which of the following is a type of particle interaction that is critical for caking in suspensions?
coagulation
Which of the following flavoring techniques for oral liquids works by keeping much of the drug in a separate phase…
suspensions
Good recommendation for compounding oral liquids are…
For wet gum method of emulsion preparation, water is mixed with acacia first
For suspensions, levigate ingredients with water-miscible*** levigating agent
Calculate for enough formulation to make 2-3% excess of suspension
Legivating as a smooth paste will help maintain sheer force
Which of the following excipients can function as a flocculating agent, nonglycogenetic sucrose substitute, wetting agent, and suspending agent?
Sodium phosphate
Methylcellulose
Sorbitol
Citric acid
Polysorbate 80
Methylcellulose
Which of the following is not a good advice to give to a patient for the usage of rectal suppositories?
Lift upper buttocks to expose rectal area
Remove all foil or other wrappings from supp to be inserted
Lie on your side, with your lower leg straight and your upper leg bent forward, toward the stomach
Avoid excessive movement or exercise for about 5 minutes.
Hold buttocks together for a few seconds and remain lying down for about 15 minutes.
Avoid excessive movement or exercise for about 5 minutes.
Which of the following is a FALSE statement about the buccal/sublingual route of drug administration?
Buccal products are generally designed for slower drug release over a sustained period of time
Drug absorbed through the buccal epithelium is drained to the hepatic portal system
Sublingual products are designed for rapid drug release over a short period of time
The buccal/sublingual membranes have relatively low permeability for most drugs
Drug absorbed through the buccal epithelium is drained to the hepatic portal system
Which of the following is least likely contributes to the poor, slow, erratic drug bioavailability of rectal drug delivery?
Complex blood drainage
Anastomoses
Patient aversion
Low surface area
Low fluid content
Patient aversion
Which of the following is FALSE statement about nicotine as a buccal product?
Nicotine release form both commit and nicorette is governed by exchange with saliva cations
Swallowed nicotine can undergo significant hepatic first past metabolism
Drug absorbed through the buccal epithelium is drained to the hepatic portal system
Chewing is critical for nicotine release from Nicorette, but not for Commit.
Drug absorbed through the buccal epithelium is drained to the hepatic portal system
Which is sometimes used as an excipient to increase viscosity, thereby reducing the settling in a suppository melt?
Propylene glycol
Polysorbate 80
Polyethylene glycol
Silica gel
silica gel
