Mitosis -- Lecture 7

Question 1

microtubule network:

polar microtubules

Answer 1

extend from spindle pole to spindle pole

Question 2

microtubule network:

aster microtubules

Answer 2

connect spindle poles to cell membrane

Question 3

microtubule network:

kinetochore microtubules

Answer 3

connect the chromosomes to the spindle poles and segregate the DNA

Question 4

microtubule dynamics/motor proteins:

CENP-E

Answer 4

1 of the motor proteins (located in kinetochore) that moves chromosomes forward and backward as the ‘+’ end grows and shortens

Question 5

microtubule dynamics/motor proteins:

Dyenin

Answer 5

1 of the motor proteins (located in kinetochore) that moves chromosomes forward and backward as the ‘+’ end grows and shortens

Question 6

anaphase A movement

Answer 6

chromosomes move away from each other

depolymerization of kinetochore microtubules

Question 7

anaphase B movement

Answer 7

spindle poles move away from each other

polymerization of polar microtubules

Question 8

telophase events:

Answer 8

1) spindle apparatus disassembles
2) nuclear membranes form around each set of chromosomes
3) chromosomes begin to decondense

Question 9

prophase events:

Answer 9

1) chromosomes condense
2) nuclear membrane breaks down
3) 2 spindle poles form and migrate to opposite ends of the cell
4) a network of microtubules will grow out from the spindle poles

Question 10

microtubule dynamics:

microtubules are hollow tubes composed of a protein called ___

Answer 10

tubulin

Question 11

microtubule dynamics:

each tubulin is made of an ___

Answer 11

alpha and beta subunit

Question 12

microtubule dynamics:

microtubules lengthen and shorten from the ___ end

Answer 12

’+’ end