Homeostasis, Immune System -- Lecture 25 Flashcards

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1
Q

immune system (definition)

A

a system of organs, tissues, and cells that protect the body from pathogens and foreign substances

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2
Q

how many major branches are there in the immune system?

A

2

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3
Q

innate immune system is the ___ line of defense

A

first

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4
Q

innate immune system ___ entry of pathogens

A

blocks

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5
Q

innate immune system blocks entry of ___

A

pathogens

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6
Q

innate immune system ___ pathogens that do enter the body

A

attacks

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7
Q

innate immune system attacks ___ that do enter the body

A

pathogens

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8
Q

innate immune system:

focus of attack is ___

A

general

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9
Q

innate immune system:

activates ___ but is not adoptable

A

immediately

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10
Q

innate immune system:

activates immediately but is not ___

A

adoptable

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11
Q

components of innate immune system:

A

physical barriers
chemical barriers
cellular defenses

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12
Q

components of innate immune system:

physical barriers (examples)

A

skin

epithelial cells that cover internal surfaces

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13
Q

components of innate immune system:

chemical barriers (examples)

A

tears
mucous
stomach acid

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14
Q

components of innate immune system:

cellular defenses (examples)

A

phagocytes

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15
Q

cells of innate immune system:

immune cells in general are called ___ or white blood cells

A

leukocytes

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16
Q

cells of innate immune system:

___ (___) are an example of leukocytes that are part of the innate immune system

A

phagocytes (cells that eat)

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17
Q

cells of innate immune system:

phagocytes are capable of ___ pathogens and destroying them (___)

A

engulfing

phagocytosis

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18
Q

cells of innate immune system:

phagocytosis (definition)

A

when phagocytes engulf pathogens and destroys them

19
Q

how do phagocytes know what to attack?

examples

A

phagocytes are pre-programmed to recognize some molecules on the surface of pathogens

Ex. proteins, sugars, etc.

20
Q

how do phagocytes know what to attack?

phagocytes recognize those substances using ___ (___)

A

pattern recognition receptors (PRRs)

21
Q

inflammatory response:

phagocytes are recruited to wounds and sites of infection by signaling molecules called ___

A

cytokines

22
Q

inflammatory response:

___ are recruited to wounds and sites of infection by signaling molecules called cytokines

A

phagocytes

23
Q

inflammatory response:

activation and recruitment of immune cells is called ___

A

inflammation

24
Q

inflammatory response:

inflammation (definition)

A

activation and recruitment of immune cells

25
Q

inflammatory response:

cytokines (definition)

A

signaling molecules that recruit phagocytes to wounds and sites of infection

26
Q

inflammatory response:

injured or infected cells release ___

A

cytokines

27
Q

inflammatory response:

___ or ___ cells release cytokines

A

injured or infected cells

28
Q

inflammatory response:

release of cytokines causes:

A

nearby blood vessels to dilate and become more permeable

29
Q

inflammatory response:

blood vessel dilation and increased blood vessel permeability causes:

A

increased blood flow

promotes phagocyte accumulation

30
Q

inflammatory response:

signs of inflammation:

A

redness, warmth, swelling (edema), pain

31
Q

2 major branches of the immune system:

A

innate immune system

adaptive immune system

32
Q

adaptive immune system:

adaptable (definition)

A

can attack new (previously unseen) pathogens (acquired immunity)

33
Q

adaptive immune system:

___ activation time (___)

A

slow

days

34
Q

adaptive immune system:

has a ___ (can be ___-term, ___-term, or ___-long)

A

memory

can be short-term, long-term, or life-long

35
Q

adaptive immune system:

focus of attack is ___

A

highly specific

36
Q

focus of adaptive attack:

1) adaptive immune response is activated by the detection of ___

A

non-self antigens

37
Q

focus of adaptive attack:

2) has the ability to distinguish ___ from ___

A

self-antigens from non-self antigens

38
Q

focus of adaptive attack:

3) able to recognize a ___ of non-self antigens

A

large diversity

39
Q

antigens and epitopes:

a non-self antigen is a ___

A

foreign molecule

40
Q

antigens and epitopes:

a non-self antigen can be a…

A

toxin
foreign body
molecule that’s on the surface of a pathogen

41
Q

antigens and epitopes:

the specific parts of an antigen that are the focus of an adaptive immune response are called ___

A

epitopes

42
Q

antigens and epitopes:

1 antigen can have ___

A

multiple epitopes

43
Q

antigens and epitopes:

epitopes (definition)

A

the specific parts of an antigen that are the focus of an adaptive immune response

44
Q

antigens and epitopes:

antigens are foreign molecules. Within structure of antigen are parts of structure that our body attacks, which are ___

A

epitopes