MIDTERM 11 - Alkaloids Flashcards
Derived from amino acid and share a heterocyclic ring with nitrogen (Types of alkaloids)
True alkaloids
Compounds which the N atom is derived from amino acids and not part of heterocyclic ring (Types of alkaloids)
Proto/amino alkaloids
Cocaine, quinine, and morphine are examples of __________
True alkaloids
Hordenine, mescaline, and yohimbine are examples of ___________
Proto/amino alkaloids
The basic carbon skeletons of which are not derived from amino acid (Types of alkaloids)
Pseudo alkaloids
Are non alkaloids that give a false positive reaction with alkaloidal reagents (Types of alkaloids)
False alkaloids
Coniine, capsaicin, ephedrine, caffeine, and theobromine are examples of __________
Pseudo alkaloids
Most alkaloids are __________, only a few alkaloids are amorphous (like emetine)
Crystalline solid
Majority of alkaloids are __________
Colorless
Colchicine and berberine are color __________
Yellow
Canadine is color __________
Orange
Salts of sanguinarine are color _________
Copper red
Alkaloidal bases and salts are soluble in __________
Alcohol
Most of the alkaloids ends in __________
“-ien”
All alkaloids are solids, except __________, __________, __________, and __________ (CANS)
Coniine, Arecoline, Nicotine, Sparteine
Derived from Coniium maculatum (poison hemlock)
Coniine
Cocaine (Stimulant, hallucinogen, or depressant)
Stimulant
Ephedrine (Stimulant, hallucinogen, or depressant)
Stimulant
Caffeine (Stimulant, hallucinogen, or depressant)
Stimulant
Tropane alkaloids (Stimulant, hallucinogen, or depressant)
Hallucinogen
Mescaline (Stimulant, hallucinogen, or depressant)
Hallucinogen
Ergot alkaloids (Stimulant, hallucinogen, or depressant)
Hallucinogen
Morphine (Stimulant, hallucinogen, or depressant)
Depressant
Codeine (Stimulant, hallucinogen, or depressant)
Depressant
Heroin (Stimulant, hallucinogen, or depressant)
Depressant
Nicotinic precursor
Nicotine
Purine precursor
Caffeine
Some alkaloids are synthesized from __________ along mevalonic acid pathway
Terpenes
Atropine is an example of __________
True alkaloid
Ephedrine is an example of __________
Protoalkaloid
Caffeine is an example of __________
Pseudo alkaloid
Reddish-brown/Brown ppt (Chemical test for alkaloids)
Wagner’s test
Wagner’s test (Positive result)
Reddish-brown/Brown ppt
White/Cream color ppt with true alkaloids (Chemical test for alkaloids)
Mayer’s test
Mayer’s test (Positive result)
White/Cream color ppt with true alkaloids
Yellow ppt with true alkaloids (Chemical test for alkaloids)
Hagger’s test
Hagger’s test (Positive result)
Yellow ppt with true alkaloids
Reddish brown ppt/Orange yellow ppt/ Orange ppt (Chemical test for alkaloids)
Dragendorff’s test
Dragendorff’s test (Positive result)
Reddish brown ppt/Orange yellow ppt/ Orange ppt
Are alkaloids that arise by inclusion of a basic nitrogen at some point in the steroid molecule; C27 compounds having cyclopentanophenanthrene moiety
Steroidal alkaloids