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DRUGS > MICRO - random bugs i.e. lice and malaria > Flashcards

MICRO - random bugs i.e. lice and malaria Flashcards

1
Q

Anti mite/louse (scabies)

A

Permethrine

Malathion

Lindane

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2
Q

Permethrin MOA and AE

A

Block NA+ channels

Neurotoxicity

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3
Q

melathion MOA

A

ACHE inhibitor

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4
Q

Lindane MOA and AE

A

blocks GABA channels

Neurotoxic

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5
Q

Malaria DOC (where no resistance

A

Chloroquine

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6
Q

Chloroquin MOA and AE

A

Block detoxification of heme to hemozoin –> toxic to plasmodium

AE = cinchonism, pruritis (especially in dark people), retinopathy, G6PD hemolysis

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7
Q

p. falciparum chloroquine reistant:

A

artemethur/lumefantrine

OR

atovaquone/proguanil

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8
Q

p. malariae

A

chloroquine

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9
Q

p. vivax or ovale rx

A

Chloroquine + primaquine for liver guys

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10
Q

Life-threatening malaria

A

quinidine or artesunate

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11
Q

Toxo: Rx and Prophylaxis

A

Rx = pyrimethamine and sulfadiazine (sulfonamide)

Prophylaxis = TMP-SMX

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12
Q

Rx t. bruci

A

suramin (blood-borne) and melarsoprol (CNS)

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13
Q

Rx t. cruzi

A

nifurtimox

OR

benznidazole

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14
Q

rx leshmaniasis

A

sodium stiboglucomate, Amphoteracin B

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15
Q

Rx giardia

A

Metronidazole

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16
Q

Rx entameba histolytica

A

Metro

OR

idoquinol (aymptomatic cyst passers)

17
Q

Rx cryptosporidium:

prevention:

A

nitazoxanide for immunocompromised

[prevent with filtered water]

18
Q

Trichomonas Rx

A

Metro

[also give to partner for prophylaxis]

19
Q

Naegleria fowleri Rx

A

Amphoteracin B

20
Q

Babesia

A

Atovaquone + azithromycin

21
Q

General nematodes

(enterobius, ascaries, strongyloides, ancylostoma, necator, trichinella)

A

Bendazoles

22
Q

Strongyloides

A

ivermectin or bendazoles

23
Q

ankylostoma or necator

A

pyrantel pamoate or bendazoles

24
Q

enterobius

A

bendazoles

25
Q

ascaries

A

bendazoles

26
Q

trichinella

A

bendazoles

27
Q

Oncocerca volvulus

A

Ivermectin

28
Q

loa loa

A

Diethylcarbamazine

29
Q

wucheria bancrofti

A

diethylcarbamazine

30
Q

toxocara canis

A

bendazoles

31
Q

tenia solium; intestinal rx

A

praziquantel

32
Q

tenia solium; cystercircosis/neurocystercircosis

A

Praziquantel + albendazoel for cysts

33
Q

diphyllobothrium latum

A

praziquantel

34
Q

echinococcus granulosus

A

Albendazole/mebendazole + surgery with chemo

35
Q

schistosoma

A

Praziquantel

36
Q

lonorchis sinensis

A

praziquantel

37
Q

Dapsone AE:

A

Erythema nodosum leprosum (fat cell inflammation)

38
Q

Clofazimine AE:

A

Red-brown skin discolouration

39
Q

Chloroquine AE:

A

retinopathy

pruritis (especially in dark people)

cinchonism

hemolytic anemia with G6PD

DRUGS (41 decks)

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