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DRUGS > CARDIO - Coagulation/clotting drugs > Flashcards

CARDIO - Coagulation/clotting drugs Flashcards

1
Q

Abciximab

A

blocks GbIIb/IIIa

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2
Q

Tirofiban

A

blocks GbIIb/IIIa (has FIB in name (prevents FIBrinogen x-linking))

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3
Q

Eptifibatide

A

blocks GbIIb/IIIa (has FIB)

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4
Q

Clopidogrel

A

blocks ADP-R

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5
Q

Prasugrel

A

blocks ADP-R

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6
Q

Ticlopidine

A

Blocks ADP-R

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7
Q

Ristocetin

A

binds GpIb to vWF

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8
Q

Agatroban

A

direct thrombin (IIa) inhibitor

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9
Q

Bivalirubin

A

direct thrombin inhibitor (IIa)

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10
Q

Dabigatran

A

direct thrombin (IIa) inhibitor

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11
Q

apixaban

A

direct Xa inhibitor (have XA in name)

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12
Q

rivaroxaban

A

direct Xa inhibitor (have XA in name)

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13
Q

fondaparinux

A

Xa inhibitor

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14
Q

Enoxaparin

A

LMVH Xa > IIa inhibition

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15
Q

dalteparin

A

LMWH Xa > IIa inhibition

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16
Q

protamine sulfate

A

heparin antidote

17
Q

warfarin

A

blocks VKOR

18
Q

alteplase

A

fibrin-selective thrombolytic

19
Q

reteplase

A

fibrin-selecive thrombolytic

20
Q

reteplase

A

fibrin-selective thrombolytic

21
Q

tPA

A

fibrin-selective thrombolytic

22
Q

streptokinase

A

non-selective thromolytic

23
Q

urokinase

A

non-selective thrombolytic

24
Q

ticagrelor

A

reversible ADP-R blocker

25
Q

cilostazol

A

PDE-III inhibitor

26
Q

Dipyridamole

A

PDE-III inhibitor

27
Q

All II inhibitors:

A

bivalirudin, agatroban, dabigatran

28
Q

All ADP-R blockers

A

Clopidogrel, ticlopidine (neutropenia), prasurgrel, ticagrelor (rev)

29
Q

Cilostasol MOA

A

Phosphodiesterase III inhibitor;􏰂cAMP in platelets, resulting in inhibition of platelet aggregation; vasodilators.

30
Q

Dipyridamole MOA

A

Phosphodiesterase III inhibitor;􏰂cAMP in platelets, resulting in inhibition of platelet aggregation; vasodilators.

DRUGS (41 decks)

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