ENDO - Signaling pathways Flashcards by Dallas Toon

Q

LH

A

cAMP

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Q

GHRH

A

cAMP

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Q

Thrombopoetin

A

RTK-associated - JAK/STAT

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Q

FSH

A

cAMP

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Q

Prolactin

A

RTK-associated - JAK/STAT

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Q

Ang-II

A

IP3

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Q

Oxytocin

A

IP3

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Q

EGF

A

Intrinsic tyrosin kinase - MAPK

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Q

GH

A

RTK-associated - JAK/STAT

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Q

Immunomodulators (IL-2, IL-6, IFN)

A

RTK-associated - JAK/STAT

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Q

ACTH

A

cAMP

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Q

RTK-associated signal via:

A

JAK/STAT - cytokines (and prolactin)

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Q

H1

A

IP3

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Q

Intracellulars

A

E, P, T T3/T4, cortisol, aldosterone, Vit D

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Q

Gastrin

A

IP3

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Q

Intrinsic tyrosin kinase signal via

A

MAPK - growth

Q

ADH-V1

A

IP3

Q

PTH

A

cAMP

Q

calcitonin

A

cAMP

Q

IGF-1

A

Intrinsic tyrosin kinase - MAPK

Q

hCG

A

cAMP

Q

TSH

A

cAMP

Q

ANP

A

cGMP

Q

TRH

A

IP3

Q

G-CSF

A

RTK-associated - JAK/STAT

Q

CRH

A

cAMP

Q

Erythropoetin

A

RTK-associated - JAK/STAT

Q

Insulin

A

Intrinsic tyrosin kinase - MAPK

Q

BNP

A

cGMP

Q

MSH

A

cAMP

Q

PDGF

A

Intrinsic tyrosin kinase - MAPK

Q

GnRH

A

IP3

Q

FGF

A

Intrinsic tyrosin kinase - MAPK

Q

ADH-V2

A

cAMP

Q

Glucagon

A

cAMP

Q

NO (EDRF)

A

cGMP

Q

Exceptions to the H = cAMP rule

[THESE ARE IP3]

A

GnRH

TRH

ADH-V1

(Histamine)