meiosis Flashcards

1
Q

asexual reproduction

A

Produces clones (genetically identical)
Single parent
Little variation in population, only through mutations
Fast and energy efficient

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2
Q

sexual reproduction

A

Meiosis produces gametes (sex cells)
2 parents: male/female
Lots of variation/diversity
Slower and energy consumptive

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3
Q

genes

A

segments of DNA that code for basic units of heredity

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4
Q

how do offspring acquire genes from parents?

A

inheriting chromosomes

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5
Q

Somatic (body) cell

A

2n = 46 chromosomes
Each pair of homologous chromosomes includes 1 chromosome from each parent

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6
Q

autosomes

A

22 pairs of chromosomes that do not determine sex

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7
Q

sex chromosomes

A

X and Y

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8
Q

female chromosome pair

A

XX

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9
Q

male chromosome pair

A

XY

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10
Q

gametes chromosomes (and egg and sperm)

A

(n=23): 22 autosomes + 1 sex chromosome
Egg: 22 + X
Sperm: 22 + X or 22 + Y

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11
Q

meiosis =

A

reduction division

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12
Q

how many times do cells divide during meiosis

A

twice

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13
Q

result of meiosis

A

4 daughter cells, each with half as many chromosomes as parent cell

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14
Q

meiosis basic phases

A

meiosis I (1st division)
interphase
prophase I
metaphase I
anaphase I
telophase I and cytokinesis
meiosis II (2nd division)
prophase II
metaphase II
anaphase II
telophase II

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15
Q

what is the purpose of meiosis I

A

1st division

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16
Q

what is the purpose of meiosis II

A

creates gametes

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17
Q

interphase

A

chromosomes replicate

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18
Q

prophase I

A

Synapsis: homologous chromosomes pair up
Tetrad = 4 sister chromatids
Crossing over at the chiasmata

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19
Q

metaphase I

A

tetrads line up

20
Q

anaphase I

A

pairs of homologous chromosomes separate
(Sister chromatids still attached by centromere)

21
Q

Telophase I & Cytokinesis:

A

Haploid set of chromosomes in each cell
Each chromosome = 2 sister chromatids
Some species: chromatin & nucleus reforms

22
Q

prophase II

A

No interphase
No crossing over
Spindle forms

23
Q

metaphase II

A

Chromosomes line up

24
Q

anaphase II

A

sister chromatids seprate

25
telophase II
4 haploid cells Nuclei reappear Each daughter cell genetically unique
26
events unique to meiosis I
Prophase I: Synapsis and crossing over Metaphase I: pairs of homologous chromosomes line up on metaphase plate Anaphase I: homologous pairs separate 🡪 sister chromatids still attached at centromere
27
crossing over
Exchange genetic material Recombinant chromosomes
28
sources of genetic information
independent assortment of chromosomes crossing over random fertilization
29
Independent Assortment of Chromosomes
Random orientation of homologous pairs in Metaphase I number of possible combinations when chromosomes assort independently = 2n 223= 8.4 million possible combinations to create a gamete
30
Random Fertilization
Any sperm + Any egg 2^23 x 2^23 = 70 trillion combinations!
31
similarity between mitosis and meiosis
both are divisions of cell nucleus
32
mitosis
Somatic cells 1 division 2 diploid daughter cells Clones From zygote to death Purpose: growth and repair No synapsis, crossing over
33
meiosis
Gametes 2 divisions 4 haploid daughter cells Genetically different-less than 1 in 8 million alike Females before birth follicles are formed. Mature ova released beginning puberty Purpose: Reproduction
34
Karyotype
a picture of an organism’s complete set of chromosomes
35
how are karyotype's arranged
from largest 🡪 smallest pair
36
purpose of karyotypes
used to determine genetic abnormalities
37
can cancer cells have abnormal chromosomes?
yes, abnormal NUMBER of chromosomes
38
HeLa Cells
Oldest and most commonly used human cell line Cervical cancer cells taken from Henrietta Lacks
39
HeLa Cells are an active version of
temomerase
40
do HeLa Cells die
no, not even after a few divisions
41
what are HeLa Cells used in research for
Develop vaccine for polio, cancer, AIDS, virus, radiation research
42
in HeLa Cells, it was estimated that
cells produced in culture exceeded # cells in Henrietta’s body
43
ethical concerns about HeLa Cells
Controversy: Cells harvested without patient consent “Discarded tissues can be commercialized” – sold for profit Genome published in 2013 without family’s consent “The Immortal Life of Henrietta Lacks” by Rebecca Skloot
44
life cycle
reproductive history of organism, from conception 🡪 production of own offspring
45
what processes alternate in sexual life cycles?
fertilization and meiosis
46
fertilization
combine gametes (sperm + egg) Fertilized egg = zygote (2n) Zygote divides by mitosis to make multicellular diploid organism