Medical Management of Type 2 Diabetes

Question 1

Which Medications increase Insulin release?

Answer 1

Sulphonylureas
Metglinides
Incretin Mimimetics
DPPIV Inhibitors

Question 2

Which medication increase excretion of glucose

Answer 2

SGLT2 Inhibitor

Question 3

Which medication improve insulin action

Answer 3

Biguanides (Metformin)
Thiazolidones
Weight Reduction
Physical activity

Question 4

1st Line Medical Medication for Typ2 Diabetes

Answer 4

Metformin which acts on liver and muscle

Question 5

Metformin is a type of which medication

Answer 5

Biguanide

Question 6

What does Metformin do?

Answer 6

Improves insulin sensitivity
Affects glucose production, decrease fatty acid synthesis
Improves receptor function
Inhibits gluconeogenic pathways
Half life 6 hours.

Question 7

Metformin is Contraindicated if Renal Failure shows Creatinine of

Answer 7

<150

Question 8

Name 3 Sulphonylureas

Answer 8

Glimepiride
Gliclazide
Glipizide

Question 9

When is sulphonylurea first choice?

Answer 9

If osmotic symptoms or HbA1c increasing rapidly titration based on home blood glucose monitoring.

Question 10

Where are sulphonyureas metabolised

Answer 10

liver

Question 11

What are DPPIV Inhibitors

Answer 11

Gliptins

Question 12

What do DPPIV Inhibitors do

Answer 12

Gliptins are DPP-4 inhibitors that delay the breakdown of incretins and thereby increase active incretin levels

Question 13

Hba1c ideal target

Answer 13

48mmol/mol