Acromegaly Flashcards

1
Q

Hypersecretion of what in Acromegaly?

A

Growth Hormone

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2
Q

Symptoms/Signs of Acromegaly? (6)

A
Spade Like Hands
Wide Feet
Coarse Facial features
Thick lips and tongue
Carpal Tunnel
Sweat
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3
Q

Complications of Acromegaly (8)

A
Headache
Chiasmal Compression
Diabetes
Hypertension
Cardiomyopathy
Sleep Apnoea
Accelerated OA
Colonic Polyps and CA
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4
Q

Diagnosis of Acromegaly

A

MRI: Pituitary Tumour

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5
Q

Management of Acromegaly

A

Somatostatin Analogues or GH Receptor Antagonist

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6
Q

Somatostatin Analogues Benefits in Acromegaly (2)

A

Normalise GH and IGF-1 Levels in over 50 Patients

Induce Tumour Shrink

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7
Q

Adverse effects of Somatostatin Analogues (2)

A

GI Symptoms

Cholesterol Gallstones mostly asymptomatic

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8
Q

Pituitary Radiotherapy can cause (1)

A

Hypopiturisim

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