Acromegaly Flashcards
1
Q
Hypersecretion of what in Acromegaly?
A
Growth Hormone
2
Q
Symptoms/Signs of Acromegaly? (6)
A
Spade Like Hands Wide Feet Coarse Facial features Thick lips and tongue Carpal Tunnel Sweat
3
Q
Complications of Acromegaly (8)
A
Headache Chiasmal Compression Diabetes Hypertension Cardiomyopathy Sleep Apnoea Accelerated OA Colonic Polyps and CA
4
Q
Diagnosis of Acromegaly
A
MRI: Pituitary Tumour
5
Q
Management of Acromegaly
A
Somatostatin Analogues or GH Receptor Antagonist
6
Q
Somatostatin Analogues Benefits in Acromegaly (2)
A
Normalise GH and IGF-1 Levels in over 50 Patients
Induce Tumour Shrink
7
Q
Adverse effects of Somatostatin Analogues (2)
A
GI Symptoms
Cholesterol Gallstones mostly asymptomatic
8
Q
Pituitary Radiotherapy can cause (1)
A
Hypopiturisim