Diabetes Mellitus Flashcards

1
Q

Type 1 is due to

A

Destruction of Beta Cells

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2
Q

Islets of Langerhan take up how much of Pancreas

A

1%

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3
Q

Beta Cells in Pancreas do what? (4)

A

Promotes glucose entry into cells
Glycogen Synth
Lipogenesis
Protein Synthesis

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4
Q

Alpha cells in Pancreas do what? (1)

A

Promote glycogen breakdown only in liver and gluconeogenesis from proteins

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5
Q

Delta cells in Pancreas do what? (2)

A

Inhibit insulin

Glucagon Secretion

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6
Q

Type 2 Diabetes is also known as

A

Non Insulin dependent

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7
Q

Type 1 Diabetes shows what immunology response

A

Lymphocytic infiltration of islets of langherhan with specific destruction of beta cells

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8
Q

Type 2 Diabetes shows what immunology response (2)

A

Reduction of cell surface receptors to insulin

Normal or increased insulin secretion

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9
Q

What virus may act as trigger for autoimmune disorders in type 1 diabetes

A

Coxsackie B

Mumps

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