Diabetes Mellitus Flashcards
Type 1 is due to
Destruction of Beta Cells
Islets of Langerhan take up how much of Pancreas
1%
Beta Cells in Pancreas do what? (4)
Promotes glucose entry into cells
Glycogen Synth
Lipogenesis
Protein Synthesis
Alpha cells in Pancreas do what? (1)
Promote glycogen breakdown only in liver and gluconeogenesis from proteins
Delta cells in Pancreas do what? (2)
Inhibit insulin
Glucagon Secretion
Type 2 Diabetes is also known as
Non Insulin dependent
Type 1 Diabetes shows what immunology response
Lymphocytic infiltration of islets of langherhan with specific destruction of beta cells
Type 2 Diabetes shows what immunology response (2)
Reduction of cell surface receptors to insulin
Normal or increased insulin secretion
What virus may act as trigger for autoimmune disorders in type 1 diabetes
Coxsackie B
Mumps