Graves Disease Flashcards
1
Q
Graves disease accounts for 70-80% of which condition?
A
Hyperthyroidism
2
Q
Graves disease is related to what pathology? (3)
A
Autoimmune
Thyroid Peroxidase Antibodies
TSH Receptor Antibodies
3
Q
Diagnosing Graves Disease? (3)
A
Goitre Expothamolos Pretibial Myxoedema Hyperthyroid TSH Receptor Antibodies
4
Q
Graves Thyroiditis looks like Histolologically (3)
A
Hyperplasia of Acinar epithelium
reduction of stored colloid
local accumulations of lymphocyte
5
Q
Which autoantibody is involved in Graves
A
IgG it binds to LATS which binds to thyroid epithelial cells and mimics TSH
6
Q
What is Pretibial Myxoedema
A
Accumulation of mucopolysaccharides in deep dermis of skin
