MCQ Variants Flashcards

1
Q
  1. The basic laboratory parameters for body water balance assessment
    include:
A

Hematocrit, MCV, Na+; Total protein, Albumin

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2
Q
  1. The lipid profile includes the following laboratory tests:
    (1 Punkt)

Total cholesterol, LDL-cholesterol, Glucose, Fibrinogen

Total cholesterol, AST, ALT, LDL-cholesterol

Total cholesterol, LDL-cholesterol, HDL- cholesterol, Triglycerides

Total cholesterol, TSH, FT3, FT4

A

Total cholesterol, LDL-cholesterol, HDL- cholesterol, Triglycerides

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3
Q
  1. Which of the following enzymes is INCREASED in PERNICIOUS anemia:

CK
ALP
LDH
ALAT

A

LDH

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4
Q
  1. Which of the following parameters is the TUMOR marker of first choice in breast cancer:
A

CA 15-3

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5
Q

The PROTHROMBIN TIME TEST is used for evaluation of the:
(1 Punkt)

Extrinsic pathway of coagulation

Intrinsic pathway of coagulation

Intrinsic and common pathways

A

EXTRINSIC pathway of coagulation

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6
Q
  1. The specimen required for the QUALITATIVE urinanalysis is:
    (1 Punkt)

first or second mid-stream morning urine portion

after toilet
diuresis urine

urine collected with catheter

all are correct

A

first or second mid-stream morning urine portion

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7
Q

Which laboratory tests are indicated in IRON DEFICIENCY ANEMIA:

CBC, morphology of erythrocytes, serum iron, ferritin, TIBC

CBC, morphology of erythrocytes, serum iron, ferritin, Vit B12

CBC, morphology of erythrocytes, serum iron, folate, TIBC

CBC, morphology of erythrocytes, serum iron, haptoglobin, TIBC

A

CBC, morphology of erythrocytes, serum iron, ferritin, TIBC

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8
Q

In HEPATOCYTOLYSIS the activity of ASAT and ALAT INCREASES:
(1 Punkt)

10 times or more above the upper reference limit

between 100 and 200 times above the upper reference limit

up to 2 times above the upper reference limit

remains unchanged

A

10 times or more above the upper reference limit

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9
Q
  1. Which vitamin deficiency predisposes to HAEMORRHAGIC DIATHESIS
    (1 Punkt)

Vit K
Vit C
Vit B12
Vit D

A

Vit K

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10
Q
  1. The densitometry narrow-based peak is called:
    (1 Punkt)

M-protein
M-gradient
Paraprotein
All are correct

A

M-gradient

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11
Q

What is the correct sequence of events leading to blood clotting:
(1 Punkt)

Vasoconstriction, platelet aggregation, coagulation

Platelet aggregation, vasoconstriction, coagulation

Vasoconstriction, coagulation, platelet aggregation

Vasoconstriction, fibrinolysis, platelet aggregation

A

Vasoconstriction, PLATELET AGGREGATION, coagulation

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12
Q

Which of the following does NOT belong to the basic laboratory tests for IRON DEFICIENCY anemia
(1 Punkt)

CBC
Haptoglobin
Morphology of erytrocytes
Reticulocytes

A

Haptoglobin

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13
Q
  1. The diagnostic sensitivity of CREATININE can be INCREASED:
    (1 Punkt)

with multiple testing

by conducting a Creatinine clearance

with measurement in CSF

with measurement in random urine

A

by conducting a Creatinine clearance

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14
Q

MAGNESIUM DEFICIENCY may cause:
(1 Punkt)

hypocalcaemia and hypokalemia

hyperthyroidism

hypernatremia

hyperosmolalit

A

HYPOcalcaemia and HYOPkalemia

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15
Q

Proteinuria ABOVE 3.5 g/24h is typical for:
(1 Punkt)

Alport syndrome

Diabetic nephropathy

IgA nephropathy

Nephrotic syndrome

A

Nephrotic syndrome

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16
Q
  1. HYPERphosphatemia may be the result of:
    (1 Punkt)

primary hyperparathyroidism

kidney failure

malabsorption

rickets

A

kidney failure

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17
Q

Which of the following statements about OSMOLALITY is true:
(1 Punkt)

Osmolality is the number of osmotically active particles in 1 liter of body water

It is theoretically calculated parameter

Osmolality is the concentration of osmotically active particles in 1 kilogram of body water

Represents the part of the formed elements to the total amount of blood

A

Osmolality is the concentration of osmotically active particles in 1 kilogram of body water

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18
Q
  1. Jaundice is also known as:
    (1 Punkt)

Icterus

Hemophilia

Anemia

Hypercholesterolemia

A

Icterus

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19
Q

Which cytochemical analysis helps to differentiate LEUKEMOID REACTION from CML
(1 Punkt)

Nonspecific esterase

Sudan Black

Leukocyte alkaline phosphatase

Periodic acid Schiff

A

Leukocyte alkaline phosphatase

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20
Q
  1. INCREASED plasma concentration of D-DIMERS indicates:
    (1 Punkt)

intravascular fibrinolysis

intravascular fibrinogenolysis

fibrinogen deficiency

thrombin deficiency

A

intravascular fibrinolysis

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21
Q

The reference range for TOTAL SERUM BILIRUBIN is:
(1 Punkt)

5.1 - 21 g/l

3.4 - 21 μmol/l;

17 - 34 μmol/l

0.8 - 8.5 μmol/l

A

3.4 - 21 μmol/l;

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22
Q

The activity of the Granulocyte ALKALINE PHOSPHATASE in LEUKEMOID REACTION is:
(1 Punkt)

in the reference range

significantly increased

significantly reduced

not informative

A

significantly increased?

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23
Q
  1. Which of the laboratory tests are indicated for the differential
    diagnosis of JAUNDICE:
    (1 Punkt)

Total bilirubin, direct bilirubin

ASAT, ALAT, ALP, GGT

All answers are correct

A

Total bilirubin, direct bilirubin

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24
Q
  1. Which of the following statements is NOT valid for DIC:
    (1 Punkt)

it can result in the formation of blood clots as well as bleeding

it is an inherited disease

it has three phases

it is often associated with an underlying condition

A

it is an inherited disease

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25
Q

The RDW measures:
(1 Punkt)

the average concentration of hemoglobin in one erytrocyte

the total number of red cells

the average volume of one erytrocyte

the variation of the red cell size

A

the variation of the red cell size

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26
Q
  1. Which of the following leukemias is likely to show an EXTREME LEUKOCYTOSIS and THROMBOCYTOSIS

Acute lymphoblastic leukemia

Acute monoblastic leukemia

Chronic lymphocytic leukemia

Chronic myeloid leukemia

A

Chronic MYELOID leukemia

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27
Q
  1. Which is the STORAGE protein of Iron:
    (1 Punkt)

Transferin

Ceruloplasmin

Ferritin

Haptoglobin

A

Ferritin

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28
Q

The laboratory result is a function of many factors influencing the FINAL
value:
(1 Punkt)

biological factors

pathological factors
factors in preanalytical stage

pathological, biological, preanalytical, analytical and postanalitical factors

A

pathological, biological, preanalytical, analytical and postanalitical factors

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29
Q
  1. The reference limits of the transaminases ASAT and ALAT are respectively:

0 - 200 U/L and 0 - 350 U/L

0 - 49 g/L and 0 - 35 g/L

0 - 49 U/L and 0 - 35 U/L

20 - 75 g/L and 25 - 100 g/L

A

0 - 49 U/L and 0 - 35 U/L

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30
Q

HYPERcalcaemia may occur in:
(1 Punkt)

primary hyperparathyroidism

rickets

hypoparathyroidism

malabsorption

A

primary hyperparathyroidism

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31
Q

A typical morphological feature of PERNICIOUS anemia are:
(1 Punkt)

microcytes

normocytes

megalocytes

microspherocytes

A

megalocytes

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32
Q

MICROALBUMINEMIA is an early marker for:
(1 Punkt)

Acute hepatitis

Chronic hepatitis

Diabetic nephropathy

Hyperparathyroidism

A

Diabetic nephropathy

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33
Q

What type is the IRON DEFICIENCY ANEMIA:
(1 Punkt)

Macrocytic, hypochromic

Macrocytic, hyperchromic

Normocytic, normochromic

Microcytic, hypochromic

A

MICROcytic, HYPOchromic

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34
Q

Mark the ERRONEOUS statement:
(1 Punkt)

PSA may be elevated in benign prostate adenoma*

PSA may increase shortly after prostate resection

PSA is a tumor marker for diagnosis of prostate cancer recurrence

PSA is an absolutely specific tumor marker for prostate tumor malignancy

A

PSA is an ABSOLUTELY SPECIFIC tumor marker for PROSTATE tumor malignancy

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35
Q

Mark the rule for collection of diuresis urine:
(1 Punkt)

collection after morning toilet

collection the whole urine from the first to the last portion

the first portion is eliminated, the last is collected

mid-stream urine portion

A

the first portion is eliminated, the last is collected

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36
Q

HYPERcholesterolemia is typical in:
(1 Punkt)

hyperthyroidism

hypothyroidism

hyperparathyroidism

hypoparathyroidism

A

HYPOthyroidism

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37
Q

Which value defines HIGH atherogenic risk: !
(1 Punkt)

Total cholesterol > 5.0 mmol/L

HDL cholesterol > 1.15 mmol/L

Total cholesterol 6.2 mmol/L

LDL cholesterol > 4.0 mmol/L

6.2 mmol/L

LDL cholesterol > 4.0 mmol/L (says high risk is more than 4.15)

A

LDL cholesterol > 4.0 mmol/L (says high risk is more than 4.15)

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38
Q

HYPERglycemia is NOT observed in:
(1 Punkt)

Diabetes
Heart attack
Insulinoma
Brain attack

A

Insulinoma

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39
Q

Which of the following individual proteins is a POSITIVE acute phase
reactant:
(1 Punkt)

Transferrin

Prealbumin

Albumin

C-reactive protein

A

C-reactive protein

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40
Q

A bone marrow biopsy shows 5% MYELOBLASTS. The most likely
diagnosis is:
(1 Punkt)

Acute myeloid leukemia

Acute lymphoblastic leukemia

Chronic lymphoblastic leukemia

Chronic myeloid leukemia

A

CHRONIC MYELOID leukemia

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41
Q

The reference limits of serum K + in adults are:
(1 Punkt)

3.5 - 5.6 mmol/ l
0.77 - 1.36 mmol/ l
2.12 - 2.62 mmol/ l
3.5-5.6 µmol/ l

A

3.5 - 5.6 mmol/ l

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42
Q

Autoantibodies against PANCREATIC ISLET CELLS (ICA) are laboratory
markers for:
(1 Punkt)

Type 1 diabetes mellitus

Type 2 diabetes mellitus

Gestational diabetes

Diabetes insipidus

A

Type 1 diabetes mellitus

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43
Q

The earliest laboratory marker of ACUTE MI is:
(1 Punkt)

AST

CK-MB

TnI

LDH

A

TnI

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44
Q

The FINAL phase of BLOOD CLOTTING includes:
(1 Punkt)

Formation of prothrombin

Formation of fibrin

Activation of factor X

Formation of thrombin

A

Formation of FIBRIN

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45
Q

The WATER SOLUBLE FRACTION of bilirubin is:
(1 Punkt)

Indirect bilirubin

Total bilirubin

Direct bilirubin

Unfractionated bilirubin

A

DIRECT bilirubin

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46
Q

Which of the following conditions is an indication for a CALCIUM test:
(1 Punkt)

disorders of the acid-base balance

rickets and osteomalacia

impaired glucose tolerance

atherosclerosis risk assessment

A

rickets and osteomalacia

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47
Q
  1. The HbA1c test is NOT applicable in DIABETIC patients with:
    (1 Punkt)

Type 1 diabetes mellitus

Type 2 diabetes mellitus

Gestational diabetes

Hemolytic anemia

A

Gestational diabetes

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48
Q

The results of the PT test are expressed as:
(1 Punkt)

mmol/l

minutes

INR, seconds and activity %

minutes and activity %

A

INR, seconds and activity %

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49
Q

Jaundice is caused by:
(1 Punkt)

Elevated uric acid in the blood

High hemoglobin in the blood

Increased bilirubin in the blood

Increased potassium in the blood

A

INCREASED BILIRUBIN in the blood

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50
Q

Which is the TRANSPORT protein of Iron:
(1 Punkt)

Ferritin

Transferin

Hemopexin

Hemosiderin

A

Transferin

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51
Q

PT is NOT prolonged in:
(1 Punkt)

overdosage of Vit K

factor VII deficiency

factor VIII defiency

liver diseases

A

factor VIII defiency

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52
Q

Which of the following laboratory parameters is used as a TUMOR
marker:
(1 Punkt)

Alpha fetoprotein

TSH

ASAT

Alkaline phosphatase

A

Alpha fetoprotein

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53
Q

Which CHROMOSOMAL ABNORMALITY occurs in CML:
(1 Punkt)

Auer body

Philadelphia (Ph) chromosome

Trisomy of chromosome 21

Deletion of the short arm of chromosome 13

A

Philadelphia (Ph) chromosome

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54
Q

Which test is used for assessment of the FINAL key phase of COAGULATION:
(1 Punkt)

Thrombin time

APTT

Hemoglobin

Bleeding time

A

Thrombin time

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55
Q

The expected laboratory constellation in ISOTONIC dehydration is:
(1 Punkt)

Decreased MCV, osmolality in the reference range, increased total protein and
hematocrit

MCV and osmolality in the reference range, increased total protein, increased
hematocrit

MCV in the reference range, high osmolality, increased total protein and hematocrit

MCV and osmolality in the reference range, increased total protein, decreased
hematocrit

A

MCV and osmolality in the reference range, INCREASED total protein, INCREASED
hematocrit

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56
Q

Which of the following pathological conditions is NOT among the main indications for examination of ALKALINE PHOSPHATASE:
(1 Punkt)

differential diagnosis of jaundice

rickets

bone diseases

prostate cancer

A

PROSTATE cancer

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57
Q

ALKALINE PHOSPHATASE does NOT increase in:
(1 Punkt)

rickets

megaloblastic anemia

cholelithiasis

osteomyelitis

A

MEGALOBLASTIC anemia

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58
Q

The ANTIBODIES of the PRIMARY IMMUNE response are:
(1 Punkt)

IgG
IgD
IgA
IgM

A

IgM

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59
Q

The TOTAL and DIRECT bilirubin are NOT indicators for:
(1 Punkt)

Liver and biliary tract diseases

Hemolytic anemias

Congenital defects of bilirubin secretion

Nephrotic syndrome

A

Nephrotic syndrome

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60
Q

Which of the following tests has the HIGHEST diagnostic reliability in
HYPERthyroidism?
(1 Punkt)

Thyroid-stimulating Hormone (TSH)

Follicle-stimulating hormone (FSH)

Parathyroid hormone

Thyrotropin-releasing hormone

A

Thyroid-stimulating Hormone (TSH)

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61
Q

The lipid profile test is used for:
(1 Punkt)

Evaluation of the glucose tolerance

Coronary risk assessment

Assessment of the liver function

Evaluation of the coagulation status

A

Coronary risk assessment

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62
Q

Indicate the reference limits for serum Na+ concentration in adults:
(1 Punkt)

136 - 151 mmol/ l
110 - 200 mmol/ l
96 - 110 mmol/ l
136-151 µmol/ l

A

136 - 151 mmol/ l

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63
Q

Which glycated proteins are used to assess the GLYCEMIA for
preceding period:
(1 Punkt)

Ferritin and transferrin

Haptoglobin and hemosiderin

HbA1c and fructosamine

Hb and ceruloplasmin

A

HbA1c and fructosamine

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64
Q

Which screening test is used for evaluation of the PLATELET and the
VASCULAR PHASE of hemostasis ?
(1 Punkt)

Bleeding time
aPTT
PT
Thrombin time

A

Bleeding time

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65
Q

The reference range for HEMOGLOBIN for MALES is:
(1 Punkt)

120-180 g/l
120-160 g/l
120-140 g/l
140-180 g/l

A

140-180 g/l

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66
Q

Which class of lipoproteins transports EXOGENOUS triglycerides:
(1 Punkt)

VLDL
Chylomicrons
HDL
LDL

A

Chylomicrons

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67
Q

Which test can be used for control and treatment with DIRECT
anticoagulants (HEPARIN):
(1 Punkt)

APTT
Fibrinogen
Platelets (PLT)
PT

A

APTT

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68
Q

Which of the following is NOT a cause of MACROCYTIC Anemia:
(1 Punkt)

Lack of intrinsic factor

Vitamin B12 deficiency

Folate deficiency

Iron deficiency

A

Iron deficiency

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69
Q

Fibrinogen is DECREASED in:
(1 Punkt)

diabetes

pregnancy

liver diseases

inflammation

A

liver diseases

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70
Q

GGT is located in the:
(1 Punkt)

cell membrane

cytoplasm

mytochondrium

cytoplasm and mytochondrium

A

cell membrane

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71
Q

ELEVATED serum FERRITIN and LOW TIBC are typical for:
(1 Punkt)

Fe deficiency anemia

Anemia of chronic disease

Megaloblastic anemia

Hemolytic anemia

A

Anemia of CHRONIC disease

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72
Q

Which of the following may be the cause for DIC:
(1 Punkt)

sepsis

cancer

complication of pregnancy

all of these conditions could lead to DIC

A

ALL of these conditions could lead to DIC

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73
Q

Reference range for the FASTING blood glucose test is:
(1 Punkt)

3.8 - 6.2 mmol/l
2.8 - 7.8 mmol/l
2.8 - 6.1 mmol/l
2.8 - 6.9 mmol/l

A

2.8 - 6.1 mmol/l

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74
Q

Which laboratory feature is NOT typical for IRON DEFICIENCY anemia:
(1 Punkt)

decreased serum iron level

decreased serum ferritin level

decreased MCH in red blood cells

decreased total iron-binding capacity

A

DECREASED TOTAL-IRON binding capacity

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75
Q

HYPERbilirubinemia with predominantly ELEVATED INDIRECT bilirubin is detected in:
(1 Punkt)

Bile obstruction

Primary biliary cirrhosis

Hemolytic anemias

Acute hepatitis

A

HEMOLYTIC anemias

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76
Q

Which of the following is a CONTRAINDICATION for OGTT:
(1 Punkt)

Gestational diabetes
Fasting blood glucose in the range 6.1-6.9 mmol/l

Patients with retinopathy, nephropathy, neuropathy

Blood glucose >11,1 mmol/l on the second hour in postprandial glucose test

A

Blood glucose >11,1 mmol/l on the second hour in postprandial glucose test

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77
Q
  1. The transaminases ASAT and ALAT have priority organ localization
    in:
    (1 Punkt)

liver, lung, placenta

liver, muscles, heart

bones, erythrocytes, muscles

heart, prostate, bones

A

liver, MUSCLES, heart

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78
Q

HYPERkalemia occurs in:
(1 Punkt)

insulin treatment

treatment with diuretics (salidiuretics)

vomiting, diarrhea, massive burns

Massive Burns

A

massive burns

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79
Q

The DRINKING solution used for the OGTT contains :
(1 Punkt)

75 g of glucose
50 g of glucose
100 g of glucose
65 g of glucose

A

75 g of glucose

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80
Q

Blood with SODIUM CITRATE is used for:
(1 Punkt)

clinical-chemistry tests

coagulation tests

hematological tests

enzyme tests

A

COAGULATION tests

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81
Q

One of the most common MISTAKES BEFORE venipuncture is:
(1 Punkt)

conversation with the patient

selection of a vein site without haematoma

applying of a tourniquet for a short time

tapping and massaging of the vein

A

tapping and massaging of the vein

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82
Q

Which changes are typical for HYPOtonic HYPERhydration:
(1 Punkt)

the water enters the intracellular space, the MCV decreases

the water enters the intracellular space, the MCV increases

water moves to the extracellular space, the MCV increases

water enters the extracellular space, the MCV does not change.

A

the water enters the INTRACELLULAR space, the MCV INCREASES

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83
Q

Direct hyperbilirubinemia is present in the following cases of jaundice, except of:
(1 Punkt)

Hemolysis

Obstruction of the bile ducts

Drug-induced liver damage

Acute hepatocytolysis

A

HEMOLYSIS

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84
Q

Screening tests for HEMORRHAGIC DIATHESIS are:
(1 Punkt)

ATIII, HC II
f.VIII

PT, APTT, TT, PLT, fibrinogen

DBC

A

PT, APTT, TT, PLT, fibrinogen

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85
Q

Laboratory markers for BLOOD CLOTTING ACTIVATION are:
(1 Punkt)

PF 1 + 2, TAT

fibrinogen, PT

platelet count, TT

Protein C, ATIII

A

PF 1 + 2, TAT

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86
Q

In BENIGN HYPERimmunoglobulinemias:
(1 βαθμός)

the monoclonal protein concentration is > 20 g/ l

the other classes of immunoglobulins are not suppressed

monoclonal proliferation is found in the bone marrow

Bence-Jones protein is detected in the urine

A

the OTHER CLASSES of immunoglobulins are NOT suppressed

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87
Q

The antibodies of the PRIMARY immune response are:
(1 βαθμός)

IgG
IgD
IgA
IgM

A

IgM

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88
Q

The INCREASED plasma D-DIMER concentration is a marker for:
(1 βαθμός)

intravascular fibrinolysis

intravascular hemolysis

fibrinogen deficiency

thrombin deficiency

A

INTRAvascular FIBRINOLYSIS

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89
Q

HIGH atherosclerotic risk is related to the following serum concentration of TOTAL CHOLESTEROL:
(1 βαθμός)

up to 4.0 mmol/l

from 1.71 to 2.28 mmol/l

> 6.5 mmol/l

up to 5.2 mmol/l

A

> 6.5 mmol/l

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90
Q

Point out the WRONG statement:
(1 βαθμός)

PSA is never elevated in benign prostate adenoma

PSA may increase immediately after prostate resection

PSA is a tumor marker for recurrence of prostate cancer

PSA is a specific tumor marker for prostate tumor malignancy

A

PSA is NEVER ELEVATED in BENIGN prostate adenoma

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91
Q

ELEVATED serum URIC ACID concentration occurs in:
(1 βαθμός)

gout

xanthinuria

reduced protein intake

overdose of uricosuric drugs

A

Gout

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92
Q

The tumor marker of first choice in BREAST cancer is:
(1 βαθμός)

СА 19-9
СА 15-3
PSA
β-HCG

A

СА 15-3

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93
Q

Laboratory tests for CONTINUOUS BLOOD GLUCOSE monitoring include:
(1 βαθμός)

urinary sugar profile test

blood sugar profile test

postprandial test

oral glucose tolerance test

A

ORAL glucose tolerance test

BLOOD SUGAR Profile Test

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94
Q

The differential blood count (DBC) provides information on:
(1 βαθμός)

the distribution of WBC in %/ absolute number in peripheral blood

maturation forms of RBC in %/ absolute number in peripheral blood

the morphology of RBC in peripheral blood

the distribution of WBC, RBC, PLT in %/ absolute number in peripheral blood

A

the distribution of WBC in %/ absolute number in peripheral blood

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95
Q

ANURIA means:
(1 βαθμός)

Diuresis 100 ml/ 24h

Diuresis in the range 500 - 100 ml/ 24h

painful urination

Diuresis exceeding 2000 ml/ 24h

A

Diuresis 100 ml/ 24h

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96
Q

ELEVATED serum ALP activity occurs in:
(1 βαθμός)

heavy physical activity

adolescents and pregnant women

intake of carbohydrate-rich foods

dehydration

A

adolescents and pregnant women

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97
Q

The diagnostic sensitivity of CREATININE can be INCREASED by:
(1 βαθμός)

multiple Urea testing

measurement of the Creatinine clearance

multiple Creatinine testing

random urine testing

A

MEASUREMENT of the Creatinine clearance

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98
Q

HYPOkalemia occurs in:
(1 βαθμός)

treatment with insulin

hemolysis

massive burns

transfusion of expired blood

A

treatment with insulin

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99
Q

Which of the following parameters does NOT indicate CHRONIC liver failure:
(1 βαθμός)

low serum albumin

prolonged prothrombin time

elevated serum bilirubin

elevated serum acid phosphatase activity

A

ELEVATED serum acid PHOSPHATASE activity

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100
Q

Which of the following tests has the HIGHEST diagnostic RELIABILITY in HYPERthyroidism:
(1 βαθμός)

Thyroid-stimulating Hormone (TSH)

Follicle-stimulating hormone (FSH)

Parathyroid hormone

Thyrotropin-releasing hormone

A

Thyroid-stimulating Hormone (TSH)

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101
Q

MEGALOBLASTIC anemias are characterized by:
(1 βαθμός)

bone marrow with erythroblastic microforms

“blue bone marrow”

bone marrow with hypochromic erythroblasts

there are no characteristic changes in the bone marrow

A

“BLUE bone marrow”

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102
Q

PROTEINURIA is estimated by measurement of:
(1 βαθμός)

150 mg/24h in diuresis

100 mg/24h in diuresis

130 mg/24h in diuresis

50 mg/24h in diuresis

A

150 mg/24h in diuresis

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103
Q

Which of the following lab parameters does NOT reflect the FIRST PHASE of the DIC:
(1 βαθμός)

PF1+2, TAT, FPA, FM

аРТТ, TT

platelet count

differential blood count

A

differential blood count

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104
Q

The rule for collecting diuresis urine is:
(1 βαθμός)

midstream urine after toilette the genitalia

the first portion is discarded, the last is collected

the whole quantity from the first to the last portion is collected

urine is collected until the vessel is full

A

the first portion is DISCARDED, the last is COLLECTED

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105
Q

The LEVEL of TIBC is a direct indicator for the amount of:
(1 βαθμός)

ferritin
transferrin
reserve Fe
hemosiderin

A

transferrin

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106
Q

Serum TRANSFERRIN is REDUCED in INFLAMMATORY PROCESSES because:
(1 βαθμός)

anemia develops during infection

the transport of the iron is disrupted

it is a “negative” reactant of the acute phase

of gut inflammation

A

it is a “NEGATIVE” reactant of the acute phase

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107
Q

The OSMOLARITY is calculated on the basis of the concentration of the following analytes:
(1 βαθμός)

urea, glucose and sodium

glucose, sodium and potassium

chloride, sodium and potassium

urea, creatinine and sodium

A

Urea, Glucose and Sodium

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108
Q

Possible causes for HEMORRHAGIC DIATHESIS are:
(1 βαθμός)

DECREASED count or IMPAIRED function of PLATELETS

VASCULAR disorders

disorders affecting PLASMA COAGULATION FACTORS and FIBRINOLYSIS

all listed

A

ALL LISTED

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109
Q

HYPERglycemia is NOT observed in:
(1 βαθμός)

diabetes mellitus

myocardial infarction

insulinoma

CNS damage

A

insulinoma

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110
Q

ACUTE HEPATOCYTOLYSIS causes INCREASED ACTIVITY MORE than 10 times of:
(1 βαθμός)

ASAT and ALAT
ALP and ACP
ALP and GGT
LDH and ACP

A

ASAT and ALAT

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111
Q

Which of the following is a CONTRAINDICATION for conducting OGTT:
(1 βαθμός)

serum glucose concentration two hours after feeding above 11.1 mmol / l

borderline elevated fasting glucose levels

evaluation of patients with unexplained retinopathy, nephropathy, neuropathy

diagnosis of gestational diabetes

A

serum glucose concentration 2 hours AFTER feeding ABOVE 11.1 mmol / l

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112
Q

Serum ACID PHOSPHATASE activity is INCREASED in:
(1 βαθμός)

stroke
acute appendicitis
myocardial infarction
prostate cancer

A

prostate cancer

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113
Q

ASPARTATE AMINOTRANSFERASE is a lab parameter for:
(1 βαθμός)

muscle damage
kidney disorders
pregnancy
rickets

A

muscle damage

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114
Q

What are expected levels of Iron and TIBC in IRON DEFICIENCY anemia:
(1 βαθμός)

decreased Iron, increased TIBC

decreased Iron, decreased TIBC

increased Iron, decreased TIBC

increased Iron, increased TIBC

A

DECREASED Iron, INCREASED TIBC

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115
Q

Laboratory markers for ACTIVATING BLOOD CLOTTING are:
(1 βαθμός)

PF1+2, ТАТ

fibrinogen

platelet count

PrC/S, ATIII

A

PF1+2, ТАТ

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116
Q

Which parameter has the HIGHEST diagnostic value in HYPERthyroidism:
(1 βαθμός)

thyroid-stimulating hormone

follicle-stimulating hormone

parathyroid hormone

thyrotropin releasing hormone

A

THYROID-stimulating hormone

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117
Q

In granulocyte LEUKEMOID REACTION, the activity of granulocyte ALKALINE PHOSPHATASE is:
(1 βαθμός)

not changed

greatly increased

greatly reduced

depends on the number of the lymphocytes

A

greatly increased

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118
Q

Flow cytometric analysis allows:
(1 βαθμός)

immunophenotyping of leukemic blasts

microchemical analysis of cellular constituents

evaluation of erythrocytes by volume

evaluation of the synthesis of hemoglobin polypeptide chains

A

immunophenotyping of leukemic blasts

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119
Q

In CHRONIC MYELOID LEUKEMIA, the ALKALINE PHOSPHATASE is:
(1 βαθμός)

not changed

greatly reduced

greatly increased

functionally active

A

Greatly REDUCED

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120
Q

HYPERbilirubinemia with a PREDOMINANT INCREASE in UNconjugated bilirubin is found in:
(1 βαθμός)

bile duct obstruction

primary biliary cirrhosis

hemolytic anemias

acute hepatitis

A

HEMOLYTIC anemias

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121
Q

MICROALBUMINURIA is a laboratory marker for:
(1 βαθμός)

assessment of type II diabetes mellitus

assessment of the risk of developing diabetic retinopathy

assessment of type I diabetes mellitus

assessment of the risk of developing diabetic nephropathy

A

assessment of the risk of developing diabetic NEPHROPATHY

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122
Q

Which enzyme has INCREASED activity in PERNICIOUS anemia:
(1 βαθμός)

CK
ALP
LDH
ALT

A

LDH

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123
Q

Morphological substrate of ACUTE LEUKEMIAS are:
(1 βαθμός)

atypical leukemic cells

erythropoietic stem cells

Philadelphia chromosome

hairy lymphocytes

A

ATYPICAL leukemic cells

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124
Q

Which COAGULATION FACTOR are involved in the INTRINSIC pathway?
(1 βαθμός)

factors XII, XI, IX, VIII

factors III, VII

factors V, X, I, II, XIII

none of the above is correct

A

factors XII, XI, IX, VIII

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125
Q

Which statement is NOT valid for DIC:
(1 βαθμός)

hereditary disease

characterized by diffuse intravascular thrombosis and secondary
hemorrhagic diathesis

can lead to multiple organ failure
takes place in three phases

A

hereditary disease

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126
Q

The EARLIEST laboratory indicator of ACUTE MI is:
(1 βαθμός)

AST
CK-MB
Troponin I
LDH

A

Troponin I

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127
Q

SMUDGE CELLS (Gumprecht shadows) in a PERIPHERAL blood smear are specific for:
(1 βαθμός)

chronic myelogenous leukemia

chronic lymphocytic leukemia

acute lymphoblastic leukemia

erythroleukemia

A

CHRONIC LYMPOcytic leukemia

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128
Q

What is NON-Selective PROTEINURIA:
(1 βαθμός)

detection of high molecular weight proteins in the urine

presence of Bence-Jones protein in the urine

detection of low molecular weight proteins in the urine

presence of lipids in the urine

A

detection of LOW molecular weight proteins in the urine

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129
Q

Typical morphological feature of PERNICIOUS anemia are:
(1 βαθμός)

megalocytes
microcytes
microspherocytes
echinocytes

A

MEGALOcytes

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130
Q

Indicate the reference limits for IONIZED CALCIUM in ADULTS:
(1 βαθμός)

2,12 - 2,62 mmol/L
2,8 - 6,1 mmol/L
1,16 - 1, 32 mmol/L
1,5 - 3,2 nmol/L

A

1,16 - 1, 32 mmol/L

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131
Q

Which types of serum bilirubin are ELVEATED in CHOLESTASIS:
(1 βαθμός)

direct bilirubin and total bilirubin

indirect bilirubin and total bilirubin

both direct and indirect bilirubin

total bilirubin and urobilinogen

A

DIRECT bilirubin and TOTAL bilirubin

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132
Q

The evaluation of serum FERRITIN is an indicator for the amount of:
(1 βαθμός)

functional Fe
transferrin
reserve Fe
hemosiderin

A

RESERVE Fe

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133
Q

The ELEVATED concentration of Ig E is due to:
(1 βαθμός)

plasmocytoma

primary biliary cirrhosis

allergies and parasitic diseases

intrauterine infections

A

allergies and parasitic diseases

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134
Q

How many grams of glucose dissolved in WATER should the patient take for OGTT:

A

75g

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135
Q

EXTENDED laboratory tests for HEMOLYTIC Anemia include:
(1 βαθμός)

osmotic resistance of erythrocytes, haptoglobin, bilirubin

immunoelectrophoresis, ceruloplasmin, ferritin

transferrin, ferritin, total protein

morphology of cells in the bone marrow

A

transferrin, ferritin, total protein

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136
Q

The serum is:
(1 βαθμός)

the liquid phase of blood taken without anticoagulant and does not include fibrinogen

the liquid phase of blood taken with an anticoagulant and does not include fibrinogen

the liquid phase of blood taken without anticoagulant and includes fibrinogen

the liquid phase of blood taken with an anticoagulant and includes fibrinogen

A

the liquid phase of blood taken WITHOUT ANTICOAGULANT and does NOT include FIBRINOGEN

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137
Q

In monoclonal gammopathy is observed:
(1 βαθμός)

a sharp peak in the field of gamma globulins (M-gradient)

overproduction of all classes of immunoglobulins

in hypoproteinemia

none of the above

A

a sharp peak in the field of gamma globulins (M-gradient)

138
Q

Which of the following individual proteins are POSITIVE reactants of the ACUTE phase:
(1 βαθμός)

prealbumin, albumin

transferrin, albumin

thromboplastin, kallikrein

fibrinogen, CRP

A

fibrinogen, CRP

139
Q

Factors CAUSING clot formation are called:
(1 βαθμός)

profibrinolytics
procoagulants
anticoagulants
antifibrinolytics

A

PROcoagulants

140
Q

Which lab parameter is NOT included in the main panel of the DIC:
(1 βαθμός)

hemoglobin
platelet count
fibrinogen
aPTT

A

hemoglobin

141
Q

IRON DEFICIENCY anemia is characterized with:
(1 βαθμός)

microcytosis
macrocytosis
microspherocytosis
megalocytosis

A

MICROcytosis

142
Q

What specimen is used for determination of THYROID hormones?
(1 βαθμός)

whole blood

serum without hemolysis and lipemia

cerebrospinal fluid

citrate plasma without hemolysis and lipemia

A

serum WITHOUT hemolysis and lipemia

143
Q

C-PEPTIDE is a laboratory marker for:
(1 βαθμός)

assessment of the insulin secretion in type I diabetes

tumor marker

hormone regulating calcium homeostasis

diabetes insipidus

A

assessment of the insulin secretion in TYPE 1 diabetes

144
Q

Which of the following conditions is an indication for serum CALCIUM testing:
(1 βαθμός)

impaired acid-base balance

rickets and osteomalacia

impaired glucose tolerance

atherogenic risk assessment

A

rickets and osteomalacia

145
Q

QUANTITATIVE determination of TOTAL CALCIUM, TOTAL PHOSPHATE and TOTAL MAGNESIUM is performed in:
(1 βαθμός)

serum and diuresis (D24)

serum and random urine

citrated plasma and diuresis (D24)

citrated plasma and random urine

A

SERUM and DIURERSIS (D24)

146
Q

Which ENZYMES are markers for CHOLESTASIS:
(1 βαθμός)

ALP and GGT

CHE and amylase

lipase and amylase

ALP and ACP

A

ALP and GGT

147
Q

Which of the following changes is NOT characteristic for the NEPHROTIC syndrome?
(1 βαθμός)

proteinuria above 5g/ 24h

bilirubinuria

peripheral edema

hypoalbuminemia

A

bilirubinuria

148
Q

THALASSEMIA syndromes are due to:
(1 βαθμός)

decreased hemoglobin synthesis

imbalance between the synthesized polypeptide chains of Hb

iron deficiency

excessive intake of vitamin B12

A

IMBALANCE between the synthesized POLYPEPTIDE chains of Hb

149
Q

BENCE-JONES PROTEINURIA is observed in cases of:
(1 βαθμός)

monoclonal gammopathy

pyelonephritis

glomerulonephritis

nephrotic syndrome

A

monoclonal gammopathy

150
Q

Which lab parameter is the EARLIEST indicator of MI:
(1 βαθμός)

CK-MB
CK
HBDH
CK-BB

A

CK-MB

151
Q

SODIUM is DECREASED and MCV is INCREASED at:
(1 βαθμός)

hypertonic dehydration

hypotonic hyperhydration

isotonic dehydration

hypertonic hyperhydration

A

HYPOtonic HYPERhydration

152
Q

The main laboratory parameters for assessment of water-electrolyte balance are:
(1 βαθμός)

Hematocrit, MCV, Na+ Total Protein, Albumin

RBC, glucose, Na+, Albumin

Albumin, Hematocrit, Urea, Creatinine
RBC, Na+, Glucose, Cholesterol

A

Hematocrit, MCV, Na+ Total Protein, Albumin

153
Q

Which of the following laboratory features is typical for CHRONIC MYELOID LEUKEMIA:
(1 βαθμός)

Left shift to Myeloblast

increased D-dimers

Leucopenia

absolute lymphocytosis

A

LEFT shift to MYELOBLAST

154
Q

Drinking coffee and smoking a cigarette BEFORE taking blood for testing is an example of:
(1 βαθμός)

a constant lab results variation

long-term lab results variation

short-term lab results variation

circadian lab results variation

A

SHORT-TERM lab results variation

155
Q

Factor IX deficiency causes:
(1 βαθμός)

hemophilia A

hemophilia B

hemophilia C

congenital immune deficiency

A

hemophilia B

156
Q

LOW serum activity of which ENZYME has clinical significance:
(1 βαθμός)

CK
LDH
ALP
CHE

A

CHE

157
Q

HYPOnatremia occurs in:
(1 βαθμός)

renal retention of water and Na +, the water retention exceeding that of Na +

renal loss of water and Na +, with water loss exceeding that of Na +

increased intake of Na +

all are true

A

renal RETENTION of water and Na +, the water RETENTION EXCEEDING that of Na +

158
Q

HYPERtriglyceridemia is a risk factor for:
(1 βαθμός)

chronic renal failure
nephrolithiasis
pancreatitis
anemia

A

pancreatitis

159
Q

Indicate the reference limits of serum Na+ concentration in ADULTS:
(1 βαθμός)

136 - 151 mmol/l
110-200 mmol/l
96-110 mmol/l
2.4 - 7.1 µmol/l

A

136 - 151 mmol/l

160
Q

MYOGLOBIN as a lab marker for:
(1 βαθμός)

acute myocardial infarction

hepatitis

malignancies

control of the anticoagulant therapy

A

ACUTE myocardial infarction

161
Q

The therapeutic range of INR in treatment with VITAMIN K ANTAGONISTS is:
(1 βαθμός)

1.0 - 2.0
2.0 - 6.0
2.0 - 4.0
0.7 - 1.2

A

2.0 - 4.0

162
Q

Which of the ENZYMES is used as a TUMOR marker:
(1 βαθμός)

LDH
AST
ALT
CHE

A

LDH

163
Q

aPTT is used for evaluation of:
(1 βαθμός)

the deficiency of f. VII

the treatment with Vit K antagonists

the intrinsic pathway of the coagulation

fibrinolysis

A

the INTRINSIC pathway of the COAGULATION

164
Q

CHOLINESTERASE ACTIVITY measurement provides information on:
(1 βαθμός)

the synthetic function of the liver

bilirubin metabolism

excretory function of the liver

detoxification function of the liver

A

the SYNTHETIC FUNCTION of the LIVER

165
Q

Calculating the ratio between URINE and SERUM OSMOLALITY is useful for:
(1 βαθμός)

assessment of homeostasis function of the kidneys

assessment of cellular and humoral immunity

assessment of hematuria

quantitative assessment of urine sediment

A

assessment of HOMEOSTASIS FUNCTION of the KIDNEYS

166
Q

The HEMOGLOBIN reference limits for women are:
(1 βαθμός)

120-180 g/l
120-160 g/l
120-140 g/l
140-180 g/l

A

120-160 g/l

167
Q

What is the specimen for evaluation of HEMOSTASIS parameters:
(1 βαθμός)

venous blood with anticoagulant heparin

venous blood with anticoagulant EDTA

venous blood with anticoagulant sodium citrate

capillary blood with anticoagulant sodium fluoride

A

VENOUS blood with anticoagulant SODIUM CITRATE

168
Q

Serum ACID PHOSPHATASE activity is increased in:
(1 Point)

stroke
acute appendicitis
myocardial infarction
prostate cancer

A

prostate cancer

169
Q

Which of the following lab parameters does NOT reflect the FIRST PHASE
of the DIC:
(1 Point)

PF1+2, TAT, FPA, FM

аРТТ, TT

platelet count

differential blood count

A

DIFFERENTIAL blood count

170
Q

Which of the following parameters does NOT indicate CHRONIC LIVER FAILURE:
(1 Point)

low serum albumin

prolonged prothrombin time

elevated serum bilirubin

elevated serum acid phosphatase activity

A

ELEVATED serum ACID PHOSPHATASE activity

171
Q

PROTEINURIA is estimated by measurement of:
(1 Point)

> 150 mg/24h in diuresis

100 mg/24h in diuresis

< 130 mg/24h in diuresis

50 mg/24h in diuresis

A

> 150 mg/24h in diuresis

172
Q

What specimen is used for determination of thyroid hormones?
(1 Point)

whole blood

serum without hemolysis and lipemia

cerebrospinal fluid

citrate plasma without hemolysis and lipemia

A

serum WITHOUT HEMOLYSIS and LIPEMIA

173
Q

The WATER SOLUBLE FRACTION of bilirubin is:
(1 Point)

Indirect bilirubin

Total bilirubin

Direct bilirubin

Unfractionated bilirubin

A

DIRECT bilirubin

174
Q

DIRECT HYPERbilirubinemia is present in the following cases of JAUNDICE, EXCEPT OF:
(1 Point)

Hemolysis

Obstruction of the bile ducts

Drug-induced liver damage

Acute hepatocytolysis

A

Hemolysis

175
Q

DBC in MEGALOBLASTIC anemia shows the following characteristics EXCEPT

a. Megakaryocytes
b. Howell-Jolie bodies
c. Increased reticulocytes
d. Hypersegmented neutrophils

A

c. INCREASED reticulocytes

176
Q

The reference limits of the transaminases ASAT and ALAT are respectively:
(1 Point)

0 - 200 U/L and 0 - 350 U/L

0 - 49 g/L and 0 - 35 g/L

0 - 49 U/L and 0 - 35 U/L

20 - 75 g/L and 25 - 100 g/L

A

0 - 49 U/L and 0 - 35 U/L

177
Q

Blood with SODIUM CITRATE is used for:
(1 Point)

clinical-chemistry tests

coagulation tests

hematological tests

enzyme tests

A

COAGULATION tests

178
Q

Which is the STORAGE protein of Iron:
(1 Point)

Transferin
Ceruloplasmin
Ferritin
Haptoglobin

A

Ferritin

179
Q

Fibrinogen is DECREASED in:
(1 Point)

diabetes
pregnancy
liver diseases
inflammation

A

LIVER diseases

180
Q

The reference range for TOTAL serum BILIRUBIN is:
(1 Point)

5.1 - 21 g/l
3.4 - 21 μmol/l
17 - 34 μmol/l
0.8 - 8.5 μmol/l

A

3.4 - 21 μmol/l

181
Q

The TOTAL and DIRECT BILIRUBIN are NOT indicators for:
(1 Point)

Liver and biliary tract diseases

Hemolytic anemias

Congenital defects of bilirubin secretion

Nephrotic syndrome

A

NEPHROTIC syndrome

182
Q

ELEVATED serum FERRITIN and LOW TIBC are typical for:
(1 Point)

Fe deficiency anemia

Anemia of chronic disease

Megaloblastic anemia

Hemolytic anemia

A

ANEMIA of CHRONIC disease

183
Q

A typical morphological feature of PERNICIOUS anemia are:
(1 Point)

microcytes
normocytes
megalocytes
microspherocytes

A

MEGALOcytes

184
Q

Which value defines HIGH ATHEROGENIC risk:
(1 Point)

Total cholesterol > 5.0 mmol/L

HDL cholesterol > 1.15 mmol/L

Total cholesterol < 6.2 mmol/L

LDL cholesterol > 4.0 mmol/L

A

LDL cholesterol > 4.0 mmol/L

185
Q

PROTEINURIA ABOVE 3.5 g/24h is typical for:
(1 Point)

Alport syndrome

Diabetic nephropathy

IgA nephropathy

Nephrotic syndrome

A

NEPHROTIC Syndrome

186
Q

HYPERcholesterolemia is typical in:
(1 Point)

hyperthyroidism
hypothyroidism
hyperparathyroidism
hypoparathyroidism

A

HYPOthyroidism

187
Q

Which of the following is NOT a cause of MACROCYTIC Anemia:
(1 Point)

Lack of intrinsic factor

Vitamin B12 deficiency

Folate deficiency

Iron deficiency

A

IRON deficiency

188
Q

Which of the following does NOT belong to the basic laboratory tests for IRON DEFICIENCY anemia
(1 Point)

CBC

Haptoglobin

Morphology of erytrocytes

Reticulocytes

A

HAPTOglobin

189
Q

The HbA1c test is NOT applicable in DIABETIC patients with:
(1 Point)

Type 1 diabetes mellitus

Type 2 diabetes mellitus

Gestational diabetes

Hemolytic anemia

A

HEMOLYTIC anemia

190
Q

Which changes are typical for HYPOonic HYPERhydration:
(1 Point)

the water enters the intracellular space, the MCV decreases

the water enters the intracellular space, the MCV increases

water moves to the extracellular space, the MCV increases

water enters the extracellular space, the MCV does not change.

A

the water enters the INTRAcellular space, the MCV INCREASES

191
Q

The expected laboratory constellation in ISOtonic DEhydration is:
(1 Point)

Decreased MCV, osmolality in the reference range, increased total protein and hematocrit

MCV and osmolality in the reference range, increased total protein, increased hematocrit

MCV in the reference range, high osmolality, increased total protein and hematocrit

MCV and osmolality in the reference range, increased total protein, decreased hematocrit

A

MCV and OSMOLALITY in the reference range, INCREASED total Protein, INCREASED Hematocrit

192
Q

Which laboratory feature is NOT typical for IRON DEFICIENCY anemia:
(1 Point)

decreased serum iron level

decreased serum ferritin level

decreased MCH in red blood cells

decreased total iron-binding capacity

A

Decreased TOTAL-IRON BINDING CAPACITY

193
Q

Which VITAMIN DEFICIENCY predisposes to HAEMORRHAGIC DIATHESIS
(1 Point)

Vit K
Vit C
Vit B12
Vit D

A

Vitamin K

194
Q

Which of the following leukemias is likely to show an EXTREME LEUKOCYTSIS and THROMBOCYTOSIS
(1 Point)

Acute lymphoblastic leukemia

Acute monoblastic leukemia

Chronic lymphocytic leukemia

Chronic myeloid leukemia

A

CHRONICC MYELOID Leukemia

195
Q

MICROALBUMINURIA is an early marker for:
(1 Point)

Acute hepatitis

Chronic hepatitis

Diabetic nephropathy

Hyperparathyroidism

A

Diabetic NEPHROPATHY

196
Q

PT is NOT prolonged in:
(1 Point)

overdosage of Vit K

factor VII deficiency

factor VIII defiency

liver diseases

A

factor VIII deficiency

197
Q

Hemolysis

A

the rupture or destruction of red blood cells

198
Q

Lipemia

A

the presence in the blood of an ABNORMALLY HIGH concentration of EMULSIFIED FAT.

FATTY
serum, WHITE serum PRESENCE

199
Q

Which of the following criteria is VALID FOR REJECTION of a specimen as INVALID?

A

IMPROPER collection tube was used,

sample HEMOLIZED, LIPEMIC, or ICTERIC,

ANTICOAGULATED
blood clotted

sample IMPROPERLY transported

200
Q

What kind of BIOLOGICAL material do we use for CLINICAL BIOCHEMISTRY analyses:

A

Serum

201
Q

PLASMA with anticoagulant SODIUM CITRATE is used for:

A

COAGULATION Test

202
Q

What BIOLOGICAL material does NOT contain FIBRINOGEN?

A

Serum

203
Q

Which are the BIOLOGICAL factors with PERMANENT activity of the variation of results

A

Sex / Race

204
Q

The RELIABLE laboratory results are:

A

Is a REAL evaluation of the ACTUAL value of the examined parameters in BIOLOGICAL fluids and
TISSUES and it presents USEFUL information

205
Q

Which of the following is NOT VALID when a BIOLOGICAL materials is taken for testing:

A

The METHOD for this test to be SELECTED correctly

206
Q

Put in the CORRECT ORDER for BLOOD COLLECTION tubes:

A

Haemoculture

Serum tube

Sodium citrate

ESR

Li heparin

EDTA

207
Q

Mark the INCORRECT answer

A

In collecting 24 hour specimens the FIRST morning specimen is to be ADDED to the container

208
Q

The EXTRINSIC pathway of coagulation is ACTIVATED by

A

TISSUE Factor

209
Q

Factors that AFFECT the lysis of a clot

A

ANTI-FIBROlytics

210
Q

Which test can be used for CONTROL and treatment with DIRECT anticoagulants (HEPARIN)

A

APTT

211
Q

Type 1 diabetes mellitus is a result of:

A

LOW or MISSING level of INSULIN in the blood

212
Q

In which type of diabetes the 2 hours postprandial test has HIGHER Diagnostic Sensitivity
THAN the Measurement of glucose at FASTING?

A

Type 2

213
Q

HbA1c is used as a test for blood glucose concentration for past PERIOD of :

A

8 - 10 Weeks

214
Q

Fibrinolysis

A

A COMPLEX of processes, which ENHANCES the LYSIS of the clot

215
Q

CAPILLARY blood is used for:

A

BLOOD GLUCOSE Levels

216
Q

Serum

A

LIQUID, NON-Cellular Portion of CLOTTED Blood

217
Q

In VIRAL Hepatitis, what can be found in the urine

A

Bilirubin POSITIVE, Urobilinogen INCREASED

218
Q

The enzyme AMYLASE is PRODUCED from

A

Pancreas

219
Q

What is the EFFECT of SOMATOTROPIN hormone of GLUCOSE blood levels?

A

INCREASES Blood GLUCOSE Levels

220
Q

FRUCTOSAMINE reference values are:

A

> 350 mmol/l

221
Q

When in HEALTHY individuals there is a HIGHER activity of MM-CK?

A

PHYSICAL Activity

222
Q

The LYSIS of blood GLUCOSE is called

A

GlycoLYSIS

223
Q

What is the FUNCTION of LDH enzymes

A

CATALYSE the CONVERSION of PYRUVATE-LACTATE

224
Q

The CK activity must NOT be investigated AFTER :

Surgical intervention

Injection

Palpation of the granulate prostate

X-ray

A

X-ray

225
Q

Coagulation factors that OBSTRUCT the clot lyses

antifibrinolytics

Profibrinolysis

Procoagulants

Anticoagulants

A

ANTI-FIBRINOlytics

226
Q

CREATINE KINASE (CK) is

Transferase

Kinase

Oxydoreductase

Hydrolase

A

Transferase

227
Q

Investigation of ALKALINE PHOSPHATASE is informative for

Transportation of amino groupies between alpha amino and alpha keto acid

Catalase transport of macroenergy phosphates

Catalase conversion pyruvate-lactate

Hydrolyse phosphate esters

A

HYDROLYSE Phosphate ESTERS

228
Q

In the serum of a NEWBORN there are:

igA, igM, igG
IgM, IgG
igA, igM
igA, IgG

A

igA, igM, igG

229
Q

Blood UREA is FINAL product of:

Metabolism of purine bases

Metabolism of amino acids

Metabolism of carbohydrates

Metabolism of lipids

A

Metabolism of AMINO ACIDS

230
Q

What do you expect to be the iron and FIBC in IRON DEFICIENT anemia

Decreased iron, increased FIBC

Decreased iron, decreased FIBC

Increased iron, decreased FIBC

Increased iron, increased FIBC

A

DECREASED Iron, INCREASED FIBC

231
Q

DYSPROTEINAEMIA is used to indicate

Hypoproteinemia

Disturbed ratio of protein fraction in electrophoresis

Euproteinemia

Hypoproteinemia

A

DISTUBED Ratio of PROTEIN fraction in ELECTROPHORESIS

232
Q

Which of the following laboratory parameters has BETTER diagnostic reliability in evaluation
of RENAL function

Urea

Uric acid

Creatinine

Total protein

A

Creatinine

233
Q

The CLINICAL RELIABILITY of laboratory results requires

High clinical and analytic reliability

Variety of factors influencing the final value

Correct interpretation of laboratory parameters

Specific requirements for Laboratory analysis

A

HIGH Clinical and Analytic reliability

234
Q

Which of the following hormones take part in the GROUP of INSULIN

Adrenaline

Progesterone

Aldosterone

Parathormone

A

Progesterone

235
Q

FRUCTOSAMINE is used as a test for blood GLUCOSE concentration for past period of:

20 days

8-10 weeks

1 week

6 month

A

20 days

236
Q

In which of the following methods is used for QUALITATIVE investigation

Immunoelectrophoretic

Enzyme methods

Electrophoresis

Immunochemical methods

A

ELECTROphoresis

237
Q

In HYPERtonic DEhydration the values of Na and MCV must be as follows

increased Na, decreased MCV

Decreased Na, increased MCV

Decreased Na, decreased MCV

Increased Na, increased MCV

A

INCREASED Na, DECREASED MCV

238
Q

What kind of test is LDH and HBDH in the ACUTE MI

Early

Earliest

Late

Retrograde

A

EARLY

239
Q

In which organ there is GLYCOGEN SYNTHESIS

Central nervous system

Muscles

Erythrocytes

Pancreas

A

Muscles

240
Q

Which of the following values of blood GLUCOSE are in the PATHOLOGICAL range in the
POSTPRANDIAL test:

Less that 7.7mmol/L

7.78-9.99mmol/L

More than 10.00 mmol/L

2.78-5.55 mmol/L

A

More than 10.00 mmol/L

241
Q

In what cases in HEALTHY individuals the activity of ALKALINE PHOSPHATASE (ALP) is over 1000
U/l:

Physical activity
Postprandial
In stress
Children

A

Children

242
Q

Blood with EDTA ANTICOAGULANT is used for the investigation for

Clinical chemistry parameters

Coagulation parameters

Hematological parameters

Heavy metals

A

HEMATOLOGICAL parameters

243
Q

Which of the following screening tests shows the DISTURBANCE in EXTRINSIC pathway of the
FIRST PHASE of COAGULATION:

A

PT

244
Q

In which values of GLUCOSE-TOLERANCE test is NOT DISTURBED:

a) at fasting, at 60 minutes, at 120 minutes are in the
reference range

b) at fasting is in the reference range, at 60 minutes-in
pathological range, at 120 minutes-boundary range

c) at 60 minutes and at 120 minutes >11.1 mmol/I

d) at 60 minutes <8.9 mmol/I, at 120 minutes <7.7 mmol/I

A

d) at 60 minutes <8.9 mmol/I, at 120 minutes <7.7 mmol/I

245
Q

What kind of BIOLOGICAL material is used for CLINICAL CHEMISTRY analyses?
(1 Point)

EDTA plasma

serum

plasma with sodium citrate

whole blood

A

Serum

246
Q

In which of the following conditions the concentration of serum Fe is HIGH?
(1 Point)

malabsorption syndrome

pregnancy

nephrotic syndrome

hemochromatosis

A

Hemochromatosis

247
Q

What is OLIGURIA?
(1 Point)

1000-2000 ml/24h urine output

100-500 ml/24h urine output

> 2000 ml/24h urine output

<100 ml/24h urine output

A

100-500 ml/24h urine output

248
Q

Which is the biologically ACTIVE FORM of CALCIUM in the blood circulation?

Ceruloplasmin

ionized and protein bound Ca

protein bound Ca

ionized Ca

A

IONIZED Ca

249
Q

Patient with DIABETES MELLITUS has Urine WITH?
(1 Point)

A

INCREASED Volume

INCREASED Specific Gravity

250
Q

A 17-year-old girl decided to go on a STARVATION diet. After 1 week of starving
herself, what substance would most likely be found in her URINE?
(1 Point)

Protein

Ketones

Glucose

Blood

A

KETONES

251
Q

What kind of BIOLOGICAL material is used for COAGULATION Parameters?
(1 Point)

whole blood

plasma with sodium citrate

serum

EDTA plasma

A

PLASMA with SODIUM CITRATE

252
Q

In ACIDOSIS the level of iСа2+ is?
(1 Point)

decreased

increased

not changed

A

INCREASED

253
Q

The TRANSPORT Protein for Ca2+ in PLASMA is?
(1 Point)

apoprotein

albumin

trasferrin

ceruloplasmin

A

Albumin

254
Q

What is the PATHOLOGICAL finding in the URINE in ACUTE Hepatitis?
(1 Point)

urobilinogen (+), bilirubin (+)

urobilinogen (-), bilirubin (+)

urobilinogen increased, bilirubin (+)

urobilinogen not increased, bilirubin (+)

A

Urobilinogen INCREASED

Bilirubin (+)

255
Q

HYPSOSIDEREMIA is observed in?
(1 Point)

frequent blood transfusions

hemolytic anemias

pregnancy

hemochromatosis

A

Pregnancy

256
Q

In which of the following conditions there is HYPER-Phosphatemia?
(1 Point)

malabsorption syndrome

treatment with corticosteroids

hypoparathyroidism

hyperparathyroidism

A

HYPO-Parathyroidism

257
Q

Which of the following does NOT result in HAEMATURIA?
(1 Point)

glomerulonephritis

Renal trauma

Renal calculus

Rhabdomyolysis

A

RHABDOMYOLYSIS

258
Q

Which of the following is a YOUNG FORM of PLATELETS?
. Single choice.
(1 Point)

proerythroblast

band cell

monoblast

megakaryoblast

A

MEGAKARYOblast

259
Q

Which parameters are included in the COMPLETE blood count (CBC) test
. Single choice.
(1 Point)

RBC, WBC, PLT, Hb, Hct, MCV, MCH, MCHC, RDW and ESR

RBC, WBC, PLT, Hb, Hct, MCV, MCH, MCHC and Differential blood count

RBC, WBC, PLT, Hb, Hct, MCV, MCH, MCHC, RDW

ESR and Differential count

A

RBC, WBC, PLT, Hb, Hct, MCV, MCH, MCHC, RDW

260
Q

CYTOCHEMICAL Analysis is:
. Single choice.
(1 Point)

Determination of routine clinical-chemistry parameters in the blood

Microscopic examination of cell chemical components by selective staining for specific substrates and / or enzymes

Clinical-chemistry analysis of the chemical composition and activity of the cells

Microscopic examination of the cell morphology in blood or bone marrow

A

MICROSCOPIC examination of cell CHEMICAL components by SELECTIVE STAINING for SPECIFIC substrates and / or enzymes

261
Q

Flowcytometry is NOT:
. Single choice.
(1 Point)

An effective laser method for analyzing the structural and functional characteristics of blood cells.

Method for the quantitative measurement of specific antigen marker expressed on and in blood cells

Method for immunophenotypic characterization of blast cells.

method for staining of blood cells

A

Method for the QUANTITATIVE measurement of SPECIFIC ANTIGEN marker expressed on and in blood cells

262
Q

For CHRONIC Granulocytic Lekuemia, differential blood count resembles:
. Single choice.
(1 Point)

thrombellogram

myelogram

densitogram

ionogram

A

Myelogram

263
Q

The LARGEEST cells in the blood that LEAVE the bloodstream to become MACROPHAGES are:
. Single choice.
(1 Point)

eosinophils
monocytes
basophils
neutrophils

A

MONOcytes

264
Q

Main MORPHOLOGICAL SUBSTRATE of ACUTE Leukemias are:
. Single choice.
(1 Point)

The youngest maturation forms of granulopoesis

Atypical blasts cells (parablasts)

Plasmoblasts

Basophils

A

The YOUNGEST MAUTRATION forms of GRANULOPOESIS

265
Q

Which of the cells does NOT develop FROM a MYELOBLAST?
. Single choice.
(1 Point)

basophil

monocyte

eosinophil

lymphocyte

A

LYMPHOcyte

266
Q

55-year-old male comes to the Emergency with a TEMPERATURE of 39 °C.

His lab findings are:

WBC 44.8
G/L

Hb 115 g/L

PLT 305 G/L

GAP (granulocyte alkaline phosphatase) 210 Units;

DBC:
7% myelocytes
5% metamyelocytes, 39% bands
41% segs
3% monocytes
4% lymphocytes
1% eosinophils
0% basophils.

. Single choice.
(2 Points)

CML

ALL

Leukocytosis with left shift

Leukemoid reaction

A

ALL!

267
Q

A 53-year-old male had noticed the onset of EASY FATIGABILITY and BRUISING.

His CBC and subsequent BONE MARROW exam were ABNORMAL.

Lab data:
WBC 78.0 G/L
Hb 73 g/L
PLT 59 G/L.

DBC - Hiatus leucaemicus.

What is the most likely diagnosis?
. Single choice.
(2 Points)

Chronic lymphocytic leukemia

Chronic granulocytic luekemia

Acute leukemia

Leukemoid reaction

A

ACUTE Leukemia

268
Q

The type of WBCs that often ARRIVES FIRST at the site of infection, is a GRANULOCYTE called:
. Single choice.
(1 Point)

basophil
eosinophil
neutrophil
monocyte

A

NEUTROphil

269
Q

A person with EOSINOPHILLIA is most likely SUFFERING from:
. Single choice.
(1 Point)

allergy or parasitic infection

anemia

autoimmune disease

diabetes

A

ALLERGY or PARASITIC Infection

270
Q

How do erythrocyte indices (MCV, MCH) change in PERNICIOUS anemia?
. Single choice.
(1 Point)

decrease
increase
do not change

A

INCREASE

271
Q

A HIGH RETICULOCYTE Count in the blood could indicate that there is a SLOW PRODUCTION of ERYTHROCYTES from
the BONE MARROW
. Single choice.
(1 Point)

True
False

A

TRUE

272
Q

THROMBOCYTOPENIA or an INCREASED TENDENCY to BLEED is a common consequence of ACUTE Leukemia.
. Single choice.

(1 Point)
True
False

A

TRUE

273
Q

Which dietary component(s) is/are needed for DNA synthesis, and thus GREATLY influence the production of RED BLOOD CELLS?
. Single choice.
(1 Point)

calcium

iron

vitamin B12 and folic acid

protein

A

Vitamin B12 and FOLIC Acid

274
Q
  1. What are the parameters included in the COMPLETE blood count (CBC) test

a. RBC, WBC, PLT, Hb, Ht, MCV, MCH, MCHC and ESR

b. RBC, WBC, PLT, Hb, Ht, MCV, MCH, MCHC and Differential count

c. RBC, WBC, PLT, Hb, Ht, MCV, MCH, MCHC

d. ESR and Differential count

A

c. RBC, WBC, PLT, Hb, Ht, MCV, MCH, MCHC

275
Q

The ratio of the volume of RED BLOOD CELLS to the TOTAL VOLUME of Blood in CBC is expressed as:

. Single choice.
(1 Point)

plasma

hematocrit

erythrocytes

serum

A

Hematocrit

276
Q

The PORTION of blood cells in whole blood in CBC is expressed as:

a. plasma
b. hematocrit
c. erythrocytes
d. serum

A

b. hematocrit

277
Q

What measure the DIFFERENTIAL COUNT CHECKING?

a. the distribution of WBC in %/absolute count in peripheral blood

b. the maturation forms of WBC in %/absolute count in peripheral blood

c. the morphology of RBC in peripheral blood

d. the distribution of WBC, RBC, PLT in %/absolute count in peripheral
blood

A

d. the distribution of WBC, RBC, PLT in %/absolute count in peripheral blood

278
Q

The type of WHITE BLOOD CELLS that often ARRIVES at the site of infection FIRST, is a GRANULOCYTES, and CONTAINS GRANULES that stain LIGHT PURPLE is a:

a. basophils
b. eosinophils
c. neutrophils
d. monocytes

A

c. neutrophils

279
Q

A HIGH RETICULOCYTE count in the blood could indicate that there is a SLOW PRODUCTION of ERYTHROCYTES from the BONE MARROW

a. True
b. False

A

TRUE

280
Q

The ERYTHROCYTE MICROforms are characteristic of:

a. megalocytic anemia

b. acute leukemia

c. iron deficiency anemia

d. chronic leukemia

A

IRON DEFICIENCY Anemia

281
Q

Which BIOCHEMICAL parameters would you investigate in case of doubt about IRON DEFICIENCY anemia.

a. serum Iron and TIBC

b. Hemoglobin electrophoresis

c. Alkaline phosphatase and acid phosphatase

d. Vit B12 and folate

A

Serum Iron and TIBC

282
Q

In the Vitamin B12 DEFICIENCY, in the blood cells is DISTURBED:

a. Iron absorption
b. Synthesis of folic acid
c. Production of an internal factor
d. DNA synthesis

A

DNA synthesis

283
Q

DBC in MEGALOBLASTIC Anemia shows the following characteristics EXCEPT

a. Megakaryocytes

b. Howell-Jolie bodies

c. Increased reticulocytes

d. Hypersegmented neutrophils

A

INCREASED RETICULOcytes

284
Q

HEMOLYTIC Anemia is caused by a DEFICIENCY of IRON in the blood

a. True
b. Not true

A

FALSE

285
Q

What are the 2 MAIN Types of THALASSEMIA?

a. Alpha and Beta Thalassemia

b. Alpha and Delta Thalassemia

c. Beta and Delta Thalassemia

d. Gamma and Delta Thalassemia

A

a. ALPHA and BETA Thalassemia

286
Q

ACUTE Leukemias by the evaluated laboratory HEMATOLOGICAL parameters are most often characterized by

a. normochromy, normocytosis, leucopenia and left shift, thrombocytosis

b. hypophosphataemia, leukocytosis, megaloblastic transformation

c. reticulocytosis, basophilically dashed erythrocytes, normal CBC

d. anemia, thrombocytopenia, most commonly moderate leukocytosis and
the presence of atypical, “blast” cells

A

ANEMIA, THROMBOCYTOPENIA, most commonly MODERATE Leukocytosis and
the PRESENCE of ATYPICAL, “BLAST” cells

287
Q

Case No C - A 6-year-old BOY had a 2 to 3 weeks history of FEVER AT NIGHT and
CERVICAL ADENOPATHY. Physical exam showed a generalized LYMPHADENOPATHY.

His
lab data are:
WBC 20.7 G/L
Hgb 109 g/L
PLT 123 G/L.

Diff count results:
1 segs
-17 lymphs
-1 monos
-81 blasts.

The BONE MARROW obtained on the patient
in Case No C was HYPER-Cellular with 80% BLASTS that were fairly SMALL and
HOMOGENOUS.

His blasts were peroxidase/SBB NEGATIVE and PAS POSITIVE.

Immunophenotyping showed
POSITIVITY for CD10, CD19/20, and CD34; cells
were NEGATIVE for CD2/3; CALLA positive.

These results are most consistent with:

a. Precursor-B ALL, CALLA type

b. T cell ALL

A

Precursor-B ALL, CALLA type

288
Q

aPTT is an indicator of:

a. deficiency of f. VII

b. Control of treatment with indirect anticoagulants

c. Evaluation of the coagulation cascade in the intrinsic pathway

d. Assessment of fibrinolysis

A

c. EVALUATION of the COAGULATION CASCADE in the INTRINSIC pathway

289
Q

What are the ways of expressing the result in a PT study?

a. %, seconds, minutes, ratio

b. Seconds,%, ratio, INR

c. Seconds,%, attitude, ISI

d. Seconds,%, ratio, minutes

A

Seconds,%, ratio, INR

290
Q

BEFORE treatment with standard HEPARIN, which indicator will you test:

a. PT
b. TT
c. aPTT
d. fibrinogen

A

aPTT

291
Q

What is the EFFECT of ASPIRIN on the processes of HEMOSTASIS?

a. Antifibrinolytic
b. Procoagulant
c. Anti-aggregate
d. Fibrinolytic

A

ANTI-Aggregate

292
Q

Typical laboratory features in DBC for CHRONIC MYELOID Leukemia is:
Single choice.
(1 Point)

Left shift up to Myelocyte

Leukocytosis

Neutropenia

Absolute lymphocytosis

A

LEFT SHIFT up to MYELOcyte

293
Q

Which of the following lab parameters does NOT reflect the FIRST PHASE of the DIC:
Single choice.
(1 Point)

PF1+2, TAT, FPA, FM

аРТТ, TT

platelet count

differential blood count

A

DIFFERENT BLOOD Count

294
Q

IRON DEFICIENCY Anemia is characterized with:
Single choice.
(1 Point)

Hypochromia

normochromic
Hypochromia

macrocytosis

A

HYPO-Chromia

295
Q

Which of the following individual proteins is NEGATIVE reactant of the ACUTE phase:

Single choice.
(1 Point)

Fibrinogen
Transferin
C-reactive protein
Alfa-1 Antitrypsin

A

Transferin

296
Q

Factors PROVIDING clot formation are called:
Single choice.
(1 Point)

profibrinolytics
procoagulants
anticoagulants
antifibrinolytics

A

PRO-Coagulants

297
Q

Which of the following enzymes has the HIGHEST activity in the LIVER:
Single choice.
(1 Point)

AST
ALT
Amylase
LDH

A

ALT

298
Q

MEGAGLOBLASTIC Anemia is due to:
Single choice.
(1 Point)

decreased hemoglobin synthesis

imbalance between the synthesized polypeptide chains of Hb

iron deficiency

deficiency of vitamin B12

A

DEFICIENCY of VITAMIN B12

299
Q

Laboratory tests for HEMOLYTIC Anemia include:
Single choice.
(1 Point)

Specialized
Hemoglobin electrophoreses, cytochemical test for HbS

Hemoglobin concentration, immunoelectrophoresis,

Cytochemical tests for blast cells, transferrin
Morphology of cells in the bone marrow

A

HEMOGLOBIN Concentration, IMMUNOELECTROPHORESIS,

300
Q

PHOSPHOR Organic compounds specifically INHIBIT:
Single choice.
(1 Point)

ALP
CHE
Amylase
CK

A

ALP

301
Q

MEGALOBLASTIC Anemias are characterized by:
Single choice.
(1 Point)

bone marrow with erythroblastic microforms

bone marrow with erythroblastic hyperplasia

bone marrow with hypochromic erythroblasts

there are no characteristic changes in the bone marrow

A

bone marrow with ERYTHOBLASTIC HYPERplasia

302
Q

LOW serum activity of which ENZYME has CLINICAL SIGNIFICANCE:
Single choice.
(1 Point)

CK
LDH
ALP
CHE

A

CHE

303
Q

Plasma

A

Liquid Phase of Blood WITH Anticoagulant, CONTAINING Fibrinogen

304
Q

Which of the following laboratory constellations confirms CHOLESTASIS:
Single choice.
(1 Point)

ALP, GGT
LDH, ALP
Cholinesterase, GGT
AST, ALT

A

ALP, GGT

305
Q

SENSITIVE marker for evaluation GLOMERULAR FILTRATION is:
Single choice.
(1 Point)

Cystatin C

Beta -2- microglobulin

Urea

Retinol-binding protein

A

Cystatin C

306
Q

The main laboratory parameters for assessment of water-electrolyte balance are:
Single choice.
(1 Point)

Hematocrit, MCV, Na+, Total Protein, Osmolality

Hematocrit, RBC, Na+, Osmolality

Hematocrit, Urea, Osmolarity, Albumin

Hematocrit, MCV, Na+, Total Protein, Glucose

A

Hematocrit, MCV, Na+, Total Protein, Osmolality

307
Q

What is the specimen for evaluation of HEMOSTASIS parameters:
Single choice.
(1 Point)

venous blood with anticoagulant heparin

venous blood with anticoagulant EDTA

venous blood with anticoagulant sodium citrate

capillary blood with anticoagulant sodium fluoride

A

venous blood with anticoagulant SODIUM CITRATE

308
Q

Which of the following conditions is an indication for serum CALCIUM testing:
Single choice.
(1 Point)

disproteinemia

screening for osteoporosis

impaired glucose tolerance

atherogenic risk assessment

A

screening for osteoporosis

309
Q

C-peptide is a laboratory marker for:
Single choice.
(1 Point)

insulin secretion

tumor marker

hormone regulating calcium homeostasis

diabetes insipidus

A

INSULIN Secretion

310
Q

HYPER-triglyceridemia is a risk factor for:
Single choice.
(1 Point)

chronic renal failure

nephrolithiasis

cardiovascular disease

anemia

A

CARDIOVASCULAR Disease

311
Q

The TUMOR MARKER for screening of PROSTATE cancer is:
Single choice.
(1 Point)

СА 19-9
СА 15-3
PSA
β-HCG

A

PSA

312
Q

PREGNANCY and BODY WEIGHT are example for:
Single choice.
(1 Point)

a constant lab results variation

long-term lab results variation

short-term lab results variation

circadian lab results variation

A

LONG-TERM lab results variation

313
Q

The level of TIBC is a INDIRECT indicator for the amount of:
Single choice.
(1 Point)

ferritin
transferrin
functional Iron
hemosiderin

A

FUNCTIONAL Iron

314
Q

Sodium is INCREASED and MCV is DECREASED at:
Single choice.
(1 Point)

hypertonic dehydration

hypotonic dehydration

isotonic dehydration

hypotonic hyperhydration

A

HYPERtonic DEhydration

315
Q

The level of glycated hemoglobin for GOOD CONTROL of diabetes is:
Single choice.
(1 Point)

lower than 7 %

> 6.5 %

lower than 6 %

6.0-6.5 %

A

6.0-6.5 %

316
Q

HYPERkalemia occurs in:
Single choice.
(1 Point)

treatment with insulin

hemolysis

metabolic acidosis

primary hyperaldosteronism

A

METABOLIC ACIDosis

317
Q

Which of the following parameters will DIFFERENTIATE DEhydration from HYPERhydration:
Single choice.
(1 Point)

Hematocrit
Platelets
Potassium
Creatinine

A

Hematocrit

318
Q

Laboratory tests with HIGHEST diagnostic reliability in HYPER-Thyroidism are:
Single choice.
(1 Point)

TSH, FT4
FSH, LH
TSH, LH
FSH, FT4

A

TSH, FT4

319
Q

aPTT is used for evaluation of:
Single choice.
(1 Point)

the deficiency of f. VII

the treatment with Vit K antagonists

the intrinsic pathway of the coagulation

fibrinolysis

A

the INTRINSIC pathway of the COAGULATION

320
Q

The test with SULFOSALICYLIC ACID is used for:

semi-quantitative analysis of protein in urine

quantitative analysis of protein in urine

semi-quantitative analysis of glucose in urine

quantitative analysis of protein in urine

A

SEMI-Quantitative analysis of PROTEIN in urine

321
Q

Mark the CORRECT answer:

serum contains all clotting factors

serum contains factors of coagulation

plasma is the liquid, noncellular portion of clotted blood

serum is the liquid, noncellular portion of clotted blood

A

SERUM is the liquid, NON-cellular portion of CLOTTED BLOOD

322
Q

WHOLE blood with EDTA is used for:

coagulation tests

clinical chemistry analysis

trace elements

CBC and DBC

A

CBC and DBC

323
Q

The express strip tests for URINALYSIS are used for:

qualitative and semi-quantitative clinical chemistry analysis

microbiological analysis of urine

quantitative clinical chemistry analysis

microscopic analysis of the sediment

A

QUALITATIVE and SEMI-QUANTITATIVE CLINICAL CHEMISTRY Analysis

324
Q

SERUM is the biological material, required for:

coagulation tests

clinical chemistry analysis

microelements

CBC and DBC

A

CLINICAL CHEMISTRY Analysis

325
Q

Mark the INCORRECT answer:

Random urine specimens should be collected in a chemically clean receptacle

Random urine specimens may be collected at any time

In collecting 24-hour specimens the first morning specimen is to be discarded

In collecting 24-hour specimens the first morning specimen is to be added in the container

A

In collecting 24-hour specimens the FIRST MORNIN specimen is to be ADDED in the container

326
Q

Good venipuncture technique follows a strict protocol. What is the maximum acceptable time to keep the tourniquet until venipuncture?

2 min
3 min
1 min
30 sec

A

1 min

327
Q

What kind of BIOLOGICAL material is used for COAGULATION Tests?

whole blood with EDTA

serum
plasma with heparin

plasma with Sodium citrate

A

PLASMA with SODIUM CITRATE

328
Q

QUANTITATIVE Measurement of PROTEIN in URINE requires

Diuresis urine (D24)

Random urine

Sterile urine

All given options are acceptable

A

Diuresis urine (D24)

329
Q

Mark the CORRECT standard conditions for preparation of the patient for clinical laboratory analysis:

  • 12 hours fasting and drinking pause, 24 hours alcohol pause, sampling between 7:00am and 9:00, no coffee and cigarette for 12 hours
  • 12 hours fasting pause, 24 hours alcohol pause, sampling between 7:00am and 9:00, no coffee and cigarette before venipuncture
  • 12 hours fasting, 24 hours alcohol pause, sampling between 7:00am and 9:00, no coffee and cigarette for 12 hours
  • 12 hours fasting and drinking pause, 12 hours alcohol pause, sampling between 7:00am and 9:00, no coffee and cigarette before venipuncture
A
  • 12 hours FASTING PAUSE, 24 hours ALCOHOL PAUSE, sampling between 7:00am and 9:00, NO coffee and cigarette BEFORE VENIPUNCTURE
330
Q

What is the CORRECT ORDER OF DRAW (blood tubes) by venipuncture
All options are acceptable

  1. coagulation tube (plasma); 2. hematology tube (whole blood); 3. serum;
  2. hematology tube (whole blood) 2. serum; 3. coagulation tube (plasma);
  3. serum; 2. coagulation tube (plasma); 3. hematology tube (whole blood)
A
  1. Serum
  2. Coagulation tube (plasma
  3. Hematology tube (whole blood)
331
Q

The main MORPHOLOGICAL SUBSTRAE of LEUKEMIAS are:

The youngest maturation forms of myelopoiesis

Parablasts

Plasmocytes

Basophils

A

PARABLASTS

332
Q

To which of the pathological conditions do you refer the following laboratory constellation:

HGB: 103 g/L
HCT 0,35 l/l
MCV: 70fl
MCH: 20 pg,

INCREASED RDW, LOW Reticulocyte count,

ferritin concentration: 3 ng/mL,
TIBC: 90 µmol/L , transferin saturation 20%?
(2 points)

Megaloblastic anemia

Acute leukemia

Primary iron deficiency anemia

Hemolytic anemia

A

MEGALOBLASTIC Anemia

333
Q

To which of the pathological conditions do you refer the following laboratory constellation:

HGB: 76 g/L
HCT 0,29 l/l
MCV: 88fl
MCH: 30 pg,

LOW reticulocyte count,

WBC: 80x109/L; Platelets: 60x109/L;

INCREASED LDH, INCREASED uric acid;

HYPER-Plastic bone marrow?
(2 points)

acute aleukemic leukemia

acute leukemia with a high percentage of parablasts in the peripheral blood

chronic myelogenous leukemia

chronic lymphogenous leukemia

A

ACUTE Leukemia with a HIGH percentage of PARABLASTS in the PERIPHERAL blood

334
Q

Which of the following NEUTROPHILLIC MATURATION forms are normally found in a PERIPHERAL blood smear?:

Reticulocytes and Myelocytes

Banded and Segmented neutrophils

Eosinophils and Monocytes

Promyelocytes and Segmented neutrophils

A

PROMYELOCTES and SEGMENTED Neutrophils

335
Q

DBC contains information about the following blood cells:

Segmented Neutrophils, Erythrocytes, etc.

Monocytes, Lymphocytes, etc.

Eosinophils, Reticulocytes, etc.

Basophils, Erythrocytes, etc.

A

SEGMENTED Neutrophils, ERYTHROCYTES, etc.

336
Q

What levels of Iron and TIBC (Total Iron Binding Capacity) do you expect in HEMOLYTIC anemia?

decreased Iron, increased TIBC

decreased Iron, decreased TIBC

increased Iron, normal TIBC

increased Iron, increased TIBC

A

INCREASED Iron, Normal TIBC

337
Q

Which of the following INDIVIDUAL proteins belong to the group of the NEGATIVE acute phase reactants?

ferritin and CRP

ferritin and transferin

albumin and
transferin

albumin and CRP

A

ALBUMIN and TRANSFERIN

338
Q

What is the FUNCTIONof FERRITIN?

Physiological form for Iron storage

pathological form for Iron storage

individual protein for Iron transport

functional Iron

A

PHYSIOLOGICAL form for Iron STORAGE

339
Q

MICROFORMS of the ERYTHROPOEITIC lineage are a typical characteristic of:

Megaloblastic anemia

Acute leukemia

Primary Iron deficiency anemia

Chronic leukemia

A

Primary Iron deficiency anemia ?/

340
Q

Which of the following forms of ERYTHROPOESIS are normally found in a PERIPHERAL blood smear?

Reticulocytes and Erythrocytes

Basophilic erythroblasts and Erythrocytes

Polychromatophilic erythroblasts and Erythrocytes

Basophilic erythroblasts and Reticulocytes

A

RETICULOCYTES and ERYTHROCYTES