MCAT BIO CH. 7 PART 1 Flashcards
What are allosomes?
Sex chromosomes
What are homologous chromosomes?
One from the mother, one from the father, two nonidentical copies of a chromosome
What are alleles?
Different versions of genes
What is meiosis?
Cell division that reduces the number of copies of each chromosome from two to one (forming haploid cells)
What cells in males and what cells in females undergo meiosis?
Spermatogonia, oogonia
What occurs in meiosis to share genomic content?
Recombination between homologous chromosomes
What is the product of meiosis?
4 haploid cells
What is different with prophase I in meiosis and mitosis prophase?
Homologous chromosomes pair with each other in synapsis
The paired homologous chromosomes are called….?
Bivalent or tetrad
Which meiosis state takes the longest and why?
Prophase I since crossing over is complex
What protein assist in the formation of tetrad during synapsis?
Protein structure called synaptonemal complex (SC)
How does the SC assist with homologous chromosomes, how does it start?
Proteins SYCP2 and SYCP3 attach to each of the two homologous chromatin structures that are to be paired
What is the lateral element of the SC?
Proteins that have attached to each of the two homologous chromatin structures
What occurs when the lateral elements of the SC are produced?
Align and attach via. centra region made of SYCP1 and other proteins
What do the lateral region and central regions form, based on crossing over?
They form the SC and work like a zipper to connect homologous chromosomes
What is different between metaphase I and metaphase in mitosis?
Tetrads are aligned at the center of the cell while in mitosis, sister chromatids are aligned
What is different between anaphase I and metaphase in mitosis?
Homologous chromosomes separate and chromatids remain together
What happens in telophase I?
Cells divides into two cells
What are the cells considered in telophase I, based on ploidicity?
Haploid; each cell has a single set of chromosomes
DNA replication occurs between meiosis I and II. T/F
False
The movements of chromosomes are the same in meiosis II and mitosis except that….?
Meiosis II has a haploid number of chromosomes mitosis has a diploid number
What happens at the end of telophase II?
Four haploid cells are produced from a. single diploid parent cell
What is nondijustion?
Homologous chromosomes or sister chromosomes failing to separate during meiosis
What is trisomy?
Gamete with two copies create a zygote with three copies of a chromosome
What is monosomy?
Gamete with no copies create a zygote with one copy of a chromosome
What is an example of nondisjunction not being lethal in humans?
Trisomy of chromosome #21 results in Down syndrome
What is an example of nondisjunction in sex chromosomes being nonlethal?
Turner syndrome: organisms with 1 X and no Y
What are the two laws of Mendel?
- Law of segregation
2. Law of independent assortment
What is the law of segregation?
Two alleles of an individual are separated and passed on to the next generation singly
What is the law of independent assortment?
Alleles of one gene will separate into games independently of alleles for another gene
What is a test cross?
individual is crossed to another individual that has a homozygous recessive genotype
If the color gene and the shape gene are right next to each other on a chromosome, will they display independent assortment?
They would display an exception called linkage
What tool is used to visualize law of segregation and independent assortment?
Punnett square
What are to ways to determine the probabilities of an outcome in a cross?
- Rule of multiplication
2. Rule of addition
What is the rule of multiplication?
Probability of two independent evens occurring found by multiplying the odds of either event alone
What is the rule of addition?
Used to calculate the chances of either of two events happening
What is incomplete dominance?
Phenotype of a heterozygote is a blended mix of both alleles
What is codominance?
Two alleles are both expressed but not blended
Other than ABO, what other main antigen is used in blood typing?
Rh (rhesus) factor
What is the pattern of the Rh blood factor?
Rh^DRh^D or Rh^DRh^d (RRand Rr) are Rh positive and RhdRhd are Rh negative
What is pleiotropism?
Expression alters many different aspects of the organism’s total phenotype
What is polygenism?
Traits influenced by many difference genes are polygenic
What is penetrance?
The likelihood that a person with a given genotype will express the expected phenotype
What type of penetrance can alleles or mutations display?
High, incomplete or low penetrance
What is epistasis?
Expression alleles for one gene is dependent on a different gene