MCAT BIO CH. 10 PART 2 Flashcards

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1
Q

What are the lower segments of the small intestine?

A

Jejunum and ileum

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2
Q

Substances not absorbed in the duodenum must be absorbed where?

A

Jejunum and Ileum

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3
Q

In what portion of the intestine is vitamin B12 absorbed?

A

Only in the ileum

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4
Q

What is the iléocaecal valve?

A

Separates the ileum from the cecum, which is the first part of the large intestine

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5
Q

What is the colon?

A

Large intestine

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6
Q

What is the role of the colon?

A

Absorb water and minerals, form and sore feces until defecation

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7
Q

What is the first part of the colon?

A

Cecum

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8
Q

What is the structure of the appendix?

A

Finger-like appendage of the cecum

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9
Q

What is the appendix primarily composed of?

A

Lymphatic tissue

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10
Q

What is the last portion of the colon?

A

Rectum

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11
Q

What is defecation controlled by?

A

Anal sphincter

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12
Q

What is the different between the internal and external portion of the anal sphincter?

A

Internal: Smooth muscle under autonomic control
External: Skeletal muscle under voluntary control

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13
Q

What is the important of colonic bacteria?

A
  1. Helps keep dangerous bacteria from proliferating due to competition
  2. Supply us with vitamin K
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14
Q

What does a GI accessory organ mean?

A

Those that play a role in digestion but are not actually part of the alimentary canal

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15
Q

What are the GI accessory organs?

A

Pancreas, liver, gallbladder and salivary glands

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16
Q

What is the purpose of pancreatic amylase?

A

Hydrolyzes polysaccharides to disaccharides

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17
Q

What is the purpose of pancreatic lipase?

A

Hydrolyzes triglycerides at the surface of a micelle

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18
Q

What is the purpose of nucleases from exocrine pancreas?

A

Hydrolyze dietary DNA and RNA

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19
Q

What is the purpose of pancreatic proteases?

A

Hydrolyzing polypeptides to di and tripeptides

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20
Q

How are pancreatic proteases secreted?

A

Secreted in their inactive zymogen forms

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21
Q

What is the role of trypsinogen in regards to exocrine pancreas?

A

A zymogen that gets converted into active form trypsin by enterokinase

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22
Q

What enzymes are activated by trypsin?

A
  1. Chymotrypsinogen
  2. Procarboxypeptidase
  3. Procollagenase
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23
Q

What does CCK secretion causes the pancreas to do?

A

Secrete enzymes

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24
Q

What does the secretion hormone cause the pancreas to do?

A

Secrete water and bicarbonate

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25
Q

What is the effect of parasympathetic and sympathetic nervous system on pancreatic secretion?

A

Para: Increases secretion
Symp: Reduces it

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26
Q

Where are the endocrine pancreas located in the pancreas?

A

Islets of Langerhans

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27
Q

What are the three types of cells in the islets of langerhans?

A
  1. Alpha cells
  2. Beta cells
  3. Omega cells
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28
Q

What do the alpha cells of the islets of langerhans?

A

Secrete glucagon in response to ow blood sugar

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29
Q

What is the function of glucagon?

A

Mobilize stored fuels by stimulating the liver to hydrolyze glycogen and release; stimulate adipocytes to release fats

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30
Q

What do the beta cells of the islets of langerhans?

A

Secrete insulin in response to elevated blood sugar

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31
Q

What is the function of insulin?

A

Stimulates removal of glucose from the blood for storage as glycogen and fat

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32
Q

What do the omega cells of the islets of langerhans?

A

Secrete somatostatin

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33
Q

What is the function of somatostatin?

A

Inhibits many digestive processes

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34
Q

What is the problem with excess glucose?

A

Destroys many physiological systems at the cellular level, including neurons, blood vessels and kidneys

35
Q

What are the three hormones that can raise blood glucose level?

A
  1. Glucagon 2. Epinephrine 3. Cortisol
36
Q

Why is it less easy to lower blood glucose?

A

Since low blood glucose levels are immediately fatal

37
Q

What is the exocrine secretory activity of the liver?

A

Secretes bile

38
Q

What are the principle ingredient of bile?

A

Bile acids, cholesterol and bilirubin

39
Q

What is bilirubin?

A

RBC breakdown

40
Q

What happens to the bile made in the liver?

A
  1. Secreted into the duodenum

2. Stored for later use in the gallbladder

41
Q

What happens to the bile when it is stored in the gallbladder?

A

Released when a fatty meal is eaten

42
Q

What is a gallstone?

A

Large crystal formed from bile made with ingredients in incorrect proportions

43
Q

The gallbladder has secretion activity. T/F

A

False: no secretory activity

44
Q

Bile released from the gallbladder is dictated by what?

A

Nervous system and endocrine system

45
Q

From where does the liver receive blood?

A
  1. Hepatic arteries - oxygenated blood

2. Hepatic portal vein - venous blood drawing the stomach and intestines

46
Q

What do hepatocytes do when the logo percolates through the liver?

A

Monitor the blood and makes changes to the body’s physiology based on what is and not present

47
Q

What can store glucose as glycogen and break it down when glucose is needed?

A

Liver and skeletal muscle

48
Q

Which organ is the only that can release glucose into the bloodstream?

A

Liver

49
Q

Why can only the liver release glucose into the bloodstream?

A

Product of glycogen breakdown is glucose-6-phosphate and only the liver contains the enzyme to dephosphorylate it

50
Q

Which organ monitors waste products from protein catabolism?

A

Liver

51
Q

How can the liver regulate ammonia?

A

Converted into urea

52
Q

Which organ assists with lipid metabolism?

A

Liver

53
Q

What are chylomicrons?

A

Molecules that transport lipid into the lymphatic system

54
Q

What is the result of chylomicrons breakdown?

A

Triglyceride, glycerol and cholestrol-rich chylomicron remnants

55
Q

What happens to chylomicron remnants?

A

Taken up by hepatocytes, combined with proteins to make lipoproteins

56
Q

Why does people with liver problems often have troubles with sealing wounds?

A

Important plasma proteins are made in the liver and secreted in the plasma

57
Q

What is different in the smooth ER of hepatocytes?

A

Contains enzymes pathways that break down drugs and toxins

58
Q

What happens based on hormonal control when the stomach is empty?

A

Gastric cells produce the hormone gherlin to stimulate appetite

59
Q

What happens based on hormonal control when the stomach is full?

A

The jejunum produces peptide YY to reduce appetite

60
Q

What is the purpose of the hormone leptin?

A

An appetite suppressant that acts as an adipostat

61
Q

What is an adipostat? Which hormone controls like that?

A

Maintaining stable lipid content in adipose tissue - leptin

62
Q

Where is hormone leptin produced?

A

White adipose tissue

63
Q

When is leptin secreted?

A

In repos-one to increased triglyceride levels and works to suppress appetite

64
Q

The effects of hormonal control of appetite Is primary mediated by…?

A

The arcuate nucleus of the hypothalamus

65
Q

Disruption of leptin signaling in animal causes what?

A

Obesity

66
Q

What are the categories of vitamins?

A

Fat soluble and water soluble

67
Q

What do fat soluble vitamins require?

A

Bile acids for solubilization and absorption

68
Q

Excess fat soluble vitamins are stored where?

A

In adipose tissue

69
Q

Excess water soluble vitamins are excreted where?

A

In urine by the kidneys

70
Q

What are the 4 fat soluble vitamins?

A

A, D, E and K

71
Q

What are the water soluble vitamins?

A

B 1, 2, 3, 6, 12, C, biotin and folate

72
Q

What is the purpose of vitamin A?

A

Visual pigment

73
Q

What is the purpose of vitamin D?

A

Control calcium deposition

74
Q

What is the purpose of vitamin E?

A

Prevents oxidation of unsaturated fats

75
Q

What is the purpose of vitamin K?

A

Formation of blood coagulation factors

76
Q

What is the purpose of vitamin B1?

A

Thiamine - enzymatic decarboxylations

77
Q

What is the purpose of vitamin B2?

A

Riboflavin - Made into FAD, electron transporter

78
Q

What is the purpose of vitamin B3?

A

Niacin - Made into NAD electron transporter

79
Q

What is the purpose of vitamin B6?

A

Pyridoxine - coenzyme involved in protein and amino acid metabolism

80
Q

What is the purpose of vitamin B12?

A

Cobalamin - coenzyme involved in the reduction of nucleotides to deoxynucleotides

81
Q

What is the purpose of vitamin C?

A

Ascorbic acid - collagen formation; deficiency = scurvy

82
Q

What is the purpose of biotin?

A

Prosthetic group essential for transport of CO2 groups

83
Q

What is the purpose of folate ?

A

Enzyme cofactor - used in transport of methylene groups, synthesis of purines and thymine, needed for normal fetal nervous system