(M) Lec 2.2: Bone Marrow Flashcards
Two types of mature bones
Cancellous or Spongy
Compact bone
Which type of bone has bone marrows?
Cancellous/Spongy
What are the two types of bone marrow?
Red and yellow
Bone marrow common in babies
Red marrow
Bone marrow common in senior and elders
Yellow marrow
Term refers to the forming of blood
Hemopoiesis
Type of cell involved in hemopoiesis which have the most potentiality and self-renewing capacity
Stem cells
Type of cell involved in hemopoiesis which have the most influence of growth factors
Progenitor cells, precursor cells, mature cells, and stem cells
Type of cell involved in hemopoiesis which have the most mitotic activity
Precursor cells
What are the precursor cells in hemopoiesis?
Blasts
Type of cell involved in hemopoiesis which have the most typical morphologic characteristics?
Mature cells
Type of cell involved in hemopoiesis which have the most differentiated functional activity
Mature cells
What are the types of hemopoiesis?
Erythropoiesis, leukopoiesis, and thrombopoiesis
How do we distinguish erythropoietic cells?
- No visible granules
- Round nucleus
How do we determine stage of development of RBCs? Based on what?
- Cell size
- Condensation of nucleus
- Cytoplasm color
Familiarize the development of erythrocytes (Or if you memorize it then slay)
From immature to mature
- Proerythroblast (Pronormoblast)
- Basophilic erythroblast
- Polychromic erythroblast
- Orthochromatic erythroblast (Normoblast)
- Polychromic erythrocyte (Reticulocyte)
- Erythrocyte
How many days before reticulocytes become erythrocytes?
3 days
Which development stage (or the name of the cell) of RBC ejects the nucleus?
Orthrochonatic erythroblast
T of F: Reticulocytes have a nucleus
False
Refers to the formation of WBC granulocytes
Granulopoiesis
How do we distinguish granulopoeitic cells?
- Highly visible granules
- Varying nucleus shape
How do we determine stage of development of granulopoiesis? Based on what?
- Type of granules
- Shape/segmentation of nucleus
Familiarize the development of granulocytes specifically neutrophils (Or if you memorize it then slay)
- N. Promyelocyte
- N. Myelocyte
- N. Metamyelocyte
- N. Band
- Neutrophil
Where are granulocytes stored?
Bone marrow
Where are WBCs formed?
Bone marrow
Two types of WBCs (granulocytes) in the blood according to function
Marginating cells and circulating cells
Familiarize the development of g
aranulocytes specifically monocytes (Or if you memorize it then slay)
- Myeloblast
- Promonocyte
- Monocyte
(If it goes to the tissues, then:
4. Immature macrophage
5. Mature macrophage)
Refers to the formation of platelets
Thrombocytogenesis
Refers to the formation of both platelets and thrombus
Thrombopoeisis
Familiarize the development of platelets (Or if you memorize it then slay)
- Megakaryoblast
- Promegakaryocyte
- Megakaryocyte
- Platelets/thrombocytes
Refers to bone marrow whose color is produced by an abundance of blood and hematopoietic cells; found in newborns up to 3 years old
Red marrow
Refers to bone marrow filled with adipocytes that exclude most hematopoietic cells; found in individuals 10 years and up
Yellow marrow
