(F) Lec 4: The Urinary System Flashcards
Familiarize the renal functions
- Regulation of balance between water and electrolytes and the acid-base balance
- Excretion of metabolic wastes along with excess water and electrolytes in urine
- Excretion of bioactive substances, drugs
- Regulation of arterial blood pressure by secretion of renin
- Secretion of erythropoietin
Enumerate the parts of the system
- Kidneys
- Ureters
- Urinary bladder
- Urethra
Location (gross anatom) of the kidney
- Posterior abdomen under cover of the ribs
- Retroperitoneal
Two main parts of kidney
Hilum and capsule
Concave part of kidney where the ff can be found:
- Blood vessels
- Lymph vessels
- Renal pelvis
Hilum
Convex, thin, and fibrous part of the kidney
Capsule
Parts of renal parenchyma
Cortex and Medulla
Renal parenchyma;
- Outer, darker
- Renal corpuscles
- Tubules
Cortex
Renal parenchyma;
- Straight structures
- Renal pyramids
- Renal columns
- Medullary rays
- Renal papilla
Medulla
Part of renal circulation which is closely associated with nephron components
Vasculature
Names according to location and shapes
BVs
Functional unit of kidney
Nephron
Two main parts of nephron
Renal corpuscle
Renal tubule
Part of nephron;
- Bowman’s capsule
- Glomerulus
Renal corpuscle
Part of nephron;
- Proximal Convoluted Tubule (PCT)
- Loop of Henle
- Distal Convoluted Tubule (DCT)
- Connecting tubules and Collecting ducts
Renal tubule
Types of nephron
Cortical and juxtamedullary
Type of nephron;
- Located almost completely in the cortex
Cortical
Type of nephron;
- Lie close to the medulla
- 1/7 of total
- Have long loops of Henle
Juxtamedullary
Refers to mass of capillary loops found in the renal corpuscle
Glomerulus
Layers of Bowman’s capsule
Visceral and Parietal
Part of renal corpuscle that receives filtered fluid
Capsular/Urinary space
Two poles in the renal corpuscle
Vascular and Tubular pole
Layer of Bowman’s capsule;
Simple squamous
At the tubular pole, the epithelium changes back to simple cuboidal
Characteristic feature of the PCT
Parietal layer
Cells found in the visceral layer of the Bowman’s capsule
Podocytes and pedicels
Cells in visceral layer;
- Stellate epithelial cells
- Cell body give rise to 1o processes
- 2o foot processes
Podocytes
Cells in visceral layer;
- Interdigitate forming elongated spaces
- Filtration slit pores
Pedicels
The slit pores of the pedicels are bridged by what?
semipermeable diaphragm called slit diaphragm
Poles;
- Afferent arteriole enters and efferent arteriole leaves
- Afferent arteriole divides into 2-5 capillaries of the glomerulus
Vascular
Poles;
PCT begins
Tubular/Urinary pole
Enumerate the filtration barrier
Fenestrated capillary endothelium
Glomerular basement
Filtration slit diaphragms
Filtration barrier;
- Block blood cell and platelets
Fenestrated capillary endothelium
Filtration barrier;
- Basal laminae of capillary
+ podocyte - Restricts large proteins &
organic anions
Glomerular basement membrane
Filtration barrier;
- Restricts small proteins and some anions
Filtration slit diaphragms