(M) Lab: Skin Flashcards
Layer of the Epidermis:
- consists of a single layer of basophilic columnar/cuboidal cells
- has INTENSE mitotic activity
Stratum Basale
These cells are clear and are found in the basal layer with dark nuclei
Melanocytes
Layer of the Epidermis:
- is the THICKEST layer
- consists of polyhedral cells that synthesize keratin filaments (tonofibrils) that converge and terminate at the desmosomes
Stratum Spinosum
These are keratin filaments that converge and terminate at the desmosomes in the Stratum Spinosum
Tonofibrils
These are known as the INTERCELLULAR bridges found in the Stratum Spinosum
Desmosomes (cell to cell adhesion)
Layer of the Epidermis:
- consists of 3-5 layers of flat polygonal cells
- their cytoplasms are filled with keratohyaline granules which are basophilic
Stratum Granulosum
T or F: The columnar/cuboidal cells of the Stratum Basale are eosinophilic
False (basophilic hence dark-staining)
T or F: The keratohyaline granules of the Stratum Granulosum are eosinophilic
False (basophilic hence dark-staining)
T or F: The Stratum Lucidum is only found in thin skin
False (thick)
*Think: The thicker the skin, the more layers it has
Layer of the Epidermis:
- found only in thick skin
- consists of a translucent layer of flat eosinophilic cells
Stratum Lucidum
What layers consist of basophilic cells/cytoplasm?
- Stratum Basale - the columnar/cuboidal cells
- Stratum Granulosum - the keratohyaline granules (IN THE CYTOPLASM)
The basophilic cytoplasm contents in the Stratum Granulosum are called?
Keratohyaline granules
T or F: The Stratum Lucidum is composed of basophilic cells
False (eosinophilic)
Keratinocytes in the Stratum Lucidum are densely packed with keratin precursors known as?
Eleidin
Layers of the Epidermis:
- consists of 15-20 flat non-nucleated cells that are CONTINUOUSLY shed
Stratum Corneum
T or F: The Stratum Corneum is shed PERIODICALLY
False (continuously)
What is it called when surface cells continuously flake off?
Exfoliate or Slough off
T or F: The Stratum Corneum is prominent in thin skin
False (thick; palms, soles, and corresponding fingers and toes)