Lymphatic System Flashcards

1
Q

What does the lymphatic system consist of?

A

Lymph
Lymphatic vessels
Lymphoid tissues and organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What do lymphoid tissues and organs include?

A

Lymphatic nodules
Lymph nodes
The thymus
The spleen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where in the body is lymphatics not found?

A

Bone marrow
Teeth
Epidermis of the skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the functions of the lymphatic system?

A
  1. Maintenance of blood volume.
  2. Generation of immune response.
  3. Transportation of dietary lipids.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Describe the flow of lymph through the body?

A
  1. Excess interstitial fluid is reabsorbed by lymphatic plexuses made of lymphatic capillaries.
  2. The capillaries merge into larger collecting lymphatic vessels.
  3. Collecting lymphatic vessels drain into fewer larger vessels called lymphatic trunks.
  4. The trunks then converge to form two large lymphatic ducts, which drain into large veins at the base of the neck.
  5. The two lymphatic ducts drain into large veins at the base of the neck on either side. Therefore, these two lymphatic ducts return lymph to the venous circulation, which eventually drains into the right atrium of the heart.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Describe the location, structure and function of lymphatic capillaries?

A

Location:
They form lymphatic plexuses that are interspersed amongst the blood capillary beds in the tissues of the body.

Structure:
1. Overlapping endothelial cells creates flap-like mini valves that are easily opened = to prevent lymphatic capillaries leaving.
2. Large junctions between endothelial cells = allows larger molecules to past through.

Function (lymphatic capillaries, [lacteals] inside the villi of the small intestine):
Absorbs dietary lipids and lipid-soluble vitamins, as these are too large to be absorbed directly into the blood.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Label the parts of the lymphatic capillaries?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Label the parts of an individual lymphatic capillary?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How are collecting lymphatic vessels formed & what are they referred to as?

A

Formed by the union of lymphatic capillaries.

Name = lymphatics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Describe the location, structure and function of lymphatic vessels?

A

Location:
Superficial lymphatic vessels follow the superficial veins within the subcutaneous tissue.
The superficial lymphatic vessels drain into the deep lymphatic vessels, which accompany deep arteries.

Structure:
Composed of tunica intima, tunica media and tunica externa & they have valves.

Function:
Afferent lymphatic vessels carry unfiltered lymph from the body tissue to the lymph nodes.
Efferent lymphatic vessels carry filtered lymph from lymph nodes to lymph nodes and lymphatic vessels upstream.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Label the lymphatic vessels?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Label the lymphatic trunks of the body?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Explain where the lymphatic trunks receive their lymph from?

A

Jugular trunks:
Receive lymph from the head and neck.

Subclavian trunks:
Receive lymph from the upper limbs, breasts and superficial thoracic wall.

Bronchomediastinal Trunks:
Receive lymph from the deep thoracic structures.

Intercostal Trunks:
Receive lymph from the thoracic wall.

Intestinal Trunk:
Receives lymph from most abdominal structures.

Lumbar Trunks:
Receive lymph from the lower limbs, abdominopelvic wall and pelvic structures.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the relationship between the lymphatic trunks and lymphatic ducts?

A

The lymphatic trunks eventually converge to form two major lymphatic channels: the right lymphatic duct (on the right side of the body) and the thoracic duct (on the left side of the body).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the function of the lymphatic ducts?

A

They return lymph to the venous circulation by emptying it into the junction of the internal jugular vein and subclavian vein on their respective sides of the body.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the venous angle?

A

The union of the internal jugular vein and subclavian vein to form the brachiocephalic vein on either side of the body.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What areas of the body do the lymphatic ducts drain?

A

The right lymphatic duct receives lymph from the ‘right upper quadrant of the body’ (right side of the head, neck and thorax).

The left lymphatic duct drains lymph from the rest of the body.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the cisterna chyli?

A

The sac-like structure where the left lymphatic duct originates from.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Where is the right lymphatic duct formed & where does it return the lymph received?

A

Formed at the convergence of the right bronchomediastinal, jugular, and subclavian trunks.

It returns the lymph received by these trunks to the venous circulation at the junction of the right subclavian and right internal jugular veins (i.e. the right venous angle).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the location of the left thoracic duct?

A

Enters the thorax by passing through the aortic opening of the diaphragm.
Termination point is at the junction of the left subclavian and left internal jugular veins (I.e. the left venous angle).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Where is the cisterna chyli located & how is it formed?

A

Located at the base of the thoracic duct on the posterior abdominal wall at the L1-L2 vertebral walls.

Formed by the junction of the lumbar, intestinal and lower intercostal trunks.

22
Q

What is the function of primary lymphoid tissues and organs & what are examples?

A

Function:
To generate new lymphocytes.

Examples:
Bone marrow & the thymus.

23
Q

What is the function of secondary lymphoid tissues and organs & what are examples?

A

Function:
Responsible for the maturation of lymphocytes.

Examples:
Lymph nodes, the spleen & lymphoid nodules.

24
Q

Explain the location and function of lymph nodes?

A

Location:
Along the path of collecting lymphatic vessels.

Function:
1. To filter lymph.
2. Help generate an immune response against antigens.

25
Q

Explain the structure of lymph nodes?

A

–> Stroma = composed of reticular connective tissue.
–> Each lymph node is surrounded by a connective tissue capsule.
–> Each region of the lymph node has an outer cortex and an inner medulla.
–> The cortex mostly contains lymphocytes that act in immune responses.
–> The medulla contains lymphocytes and macrophages that deal with antigens and enhance immune responses.

26
Q

Explain the circulation of lymph through the limph nodes?

A

Lymph enters the lymph nodes via multiple afferent lymphatic vessels and exits via fewer efferent lymphatic vessels.

27
Q

How’s does lymph flow through the lymph nodes?

A

Lymph flows through a series of spaces called lymphatic sinuses that are present in both the cortex (called cortical sinuses) and the medulla (called medullary sinuses).

28
Q

Explain the draining process of lymph within superficial and deep lymph nodes?

A

Lymph from the superficial lymph nodes drains into the deep lymph nodes (‘from superficial to deep’).

29
Q

What is the relationship between lymph nodes and cancer?

A

Lymph nodes are the initial site of metastasis in many cancers.

30
Q

Label the lymph node structure?

A
31
Q

Label the human lymph node?

A
32
Q

Identify examples of major groups of lymph nodes?

A
33
Q

Identify the size of the thymus in infants and young children?

A

Large in infants and young children.

34
Q

Explain what happens to the thymus as we age?

A

It becomes smaller and loses its organised structure while being replaced by adipose connective tissue.

35
Q

Identify the size of the thymus in adults?

A

It is very small and mostly consists of adipose connective tissue, making it practically non-functional.

36
Q

Identify the location of the thymus in young children?

A

Located in the inferior neck and extends into the anterior part of the mediastinum where it partially overlies the heart.
Most of the thymus is found directly posterior to the sternum, covering the origins of the great vessels.

37
Q

What is an important function of the thymus during youth?

A

It is the site of maturation of T-lymphocytes (white blood cells) responsible for fighting infections.

38
Q

What are other functions of the thymus?

A
  1. Produces hormones (thymulin and thymosin), which regulate immune cells production.
  2. Synthesizes hormones such as insulin and melatonin.
39
Q

What are the main functions the spleen?

A
  1. Filters blood rather than lymph by bringing blood into contact with lymphocytes so that antigens detected in the blood can be destroyed.
  2. Provides a site for lymphocyte proliferation and immune functions.
  3. Storing of platelets (which assist with blood clotting) and erythrocytes, or red blood cells.
  4. Destroys aged or defective platelets and erythrocytes, as well as blood-borne pathogens.
  5. In the foetus, the spleen acts as a haematopoietic site (i.e. a site of blood cell formation).
40
Q

Identify the location of the spleen?

A

Located in a region of the abdominopelvic cavity called the left upper quadrant.

–> Sits directly underneath the left dome of the diaphragm.
–> Is posterolateral to the stomach and lateral to the pancreas.
–> Is superior to the large intestine.
–> Is lateral to the left kidney.

41
Q

Explain the structure of the spleen?

A

Has 2 surfaces:

Diaphragmatic surface (a posterolateral surface) = is in contact with the diaphragm and lies against the left lower ribs.

Visceral surface (a anteromedial surface) = bears the impressions of several abdominal organs that are in immediate contact with the spleen (‘viscera’ = organs).

42
Q

What are the examples of the lymphoid nodules aggregations?

A

Mucosa-associated lymphoid tissue (MALT)
The tonsils

43
Q

Identify the location of the lymphoid nodule aggregations?

A

Mucosa-associated lymphoid tissue (MALT):
The distal part of the small intestine called the ‘ileum’, where the aggregations are called Peyer’s patches.

Wall of the appendix:
A small tubular pouch connected to the proximal part of the large intestine called the caecum.

Tonsils:
Found at the entrances of the respiratory and digestive tracts.

44
Q

Name and identify the location of the different type of tonsils?

A

Pharyngeal tonsil (referred as the ‘adenoids’):
In the posterior wall of the nasopharynx.

Palatine tonsils:
On either side of the soft palate.

Lingual tonsil:
On the posterior aspect of the tongue.

Tubal tonsils:
Surrounding the openings of the auditory tubes.

45
Q

Identify the labelled lymphoid structures?

A
46
Q

Identify the flow of lymph through the body?

A
47
Q

Where does the lymph come from and where does it drain into?

A
  • Originates from interstitial fluid.
  • Drains into the venous system via the thoracic duct or right lymphatic duct.
48
Q

What is the function of the thoracic duct? Where does it drain?

A

Function:
Collects lymph from most of the body.

Where does it drain:
Drains the lymph into the venous system at the junction of the left subclavian and left internal jugular veins.

49
Q

What is the function of the right lymphatic duct? Where does it drain?

A

Function:
Collects lymph from the right upper part of the body.

Where does it drain:
Drains the lymph into the venous system at the junction of the right subclavian and right internal jugular veins.

50
Q

What is the thymus? Where is it located?

A

What is the thymus:
A primary lymphoid organ involved in T-cell maturation.

Location:
In the upper anterior part of the chest (behind the sternum).

51
Q

What are locations of the main groups of lymph nodes?

A
  • Neck (cervical)
  • Armpits (axillary)
  • Chest (mediastinal)
  • Abdomen (mesenteric)
  • Groin (inguinal)