Liver Gallbladder Pancreas Flashcards
What do alpha cells of islets of langerhands secrete? Beta? Delta?
Alpha
Insulin
Somatostatin
Where are zymogen granules located?
Apex of serous acini
Where do centroacinar cells open to?
Intercalated duct
Does the pancreas have striated ducts?
No
What do intercalated ducts connect to?
Intralobular ducts
WHat is the most common endocrine disorder in the dog?
Diabetes
What happens during acute pancreatitis?
Digestive enzymes are released in to local tissue
What endocrine does the liver secrete?
Angiotensinogen
What exocrine does the liver secrete?
BIle
Main function of liver
Fat, carb, protein metabolism
Storage
Secretion
Why are there many mitochondria in hepatocytes (and much SER)
Detoxification
Where are kupffer cells found?
sinusoids
What make the trabeculae of liver?
Hepatocytes
Is blood flow continuous or opposite to bile and lymph flow?
Opposite
Describe the flow of blood through venous system & liver
Portal vein Sinusoids Central veins Hepatic vein caudal vena cava right atrium
What is the space of disse?
space between hepatocytes where lymph can flow while blood runs opposite direction through central vein
What communicates bile between hepatocytes?
Bile canaliculi
WHat is the purpose of Ito cells?
Store fat and vitamin A
What is the acinus of rappaport?
connection between two hepatocytes creates “backbone”
What are the zones based on the acinus of rappaport?
Zone 1: best nutritional supply
Zone 2: intermeidae oxygen supply
Zone 3: hepaocytes have poorest supply and more susceptible
Where is the majority of fetal hemopoiesis?
liver
What is the purpose of the gallbladder?
Stores bile
WHat species do not have a gallbladder?
horse
deer
rat
What is the epithelium of the gallbladder?
simple columnar epithelium
What is the sphincter of oddi?
releases bile to major duondenal papilla
What stimulates release of bile?
CCK
What hormones are needed for exocrine function of pancreas?
Chymotrypsinogen
lipase
amylase
