Lipolysis Flashcards
What happens when dietary energy is limited?
Fatty acids from triglycerides are mobilized from adipocytes into circulation for use by the body.
How are triglycerides broken down during lipolysis?
Lipase hydrolyzes triglycerides into fatty acids and glycerol for use in the body.
What hormones stimulate lipolysis?
Adrenaline and noradrenaline, Adrenocorticotropic hormone (ACTH),
Glucagon and growth hormone,
Thyroid-stimulating hormone (TSH) and thyroxine.
What role does insulin play in lipolysis?
Insulin antagonizes the lipolytic effects of the hormones that stimulate fat breakdown. Which results in insulin resistance.
How does insulin resistance affect fat storage?
Insulin resistance (e.g., in Type 2 diabetes) leads to central adiposity (fat accumulation around the abdomen).
