Leukocyte differential count. Flashcards

1
Q

Name 5 kinds of leukocytes in blood and their categorization?

A

Polymorphonuclear granulocytes : neutrophils, eosinophils and basophils.
Mononuclear agranulocytes: Monocytes and lymphocytes.

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2
Q

How are leukocyte production regulated?

A

Produced at varying rates according to the changing needs of the body.

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3
Q

What is WBC differential count?

A

Percentage distribution of each population within the total leukocyte count.

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4
Q

How is the differential count performed?

A

Meander movement, count 100 leukocytes. Differentiate and sort into populations based on morphological appearance.

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5
Q

Difference between :

  1. polymorphonuclear granulocytes
  2. mononuclear agranulocytes
A
  1. have a segmented nucleus with several lobes, cytoplasm contain granules.
  2. have a single large, non-segmented nucleus and few granules
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6
Q

Function of neutrophils?

A

phagocytic specialist,first defenders during bacterial innflamm, important in innflammatory response.

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7
Q

Eosinophils are associated with?

A

hypersensitivity conditions, internal parasite infection

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8
Q

Basophils are associated with?

A

allergic reactions and innflammations (tissue derivates = mast cells)

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9
Q

Which substances are produced by granulocytes?

A

Histamine and heparin.

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10
Q

Categorize cells of lymphocytes?

A

B-cells hormonal defenders
T-cells cell-cell mediatet immune response
-T-helper, initiator
-T-cytotoxic destroy infected cells
-T-supressor balance other two by supressing immune response

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