Lecture One - Skin Flashcards

1
Q

How much of your body weight is contributed by skin

A

16%

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2
Q

How much surface are does skin cover

A

1.5-2m^2

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3
Q

Why did we adapt to have bare sweaty skin

A
  • climate change meant we started running in open grass land
  • no hair meant efficient heat loss - through sweat glands
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4
Q

Functions of skin and accessory structures

A
  • Protect underlying tissue and organs from impact, abrasion, fluid loss and chemical attack
  • Ecrete salt, water and organic wast through intergumentary glands
  • Maintain a constant body temperature through evaporative cooling and insulation
  • Production of melanin which protects underlying tissue from ulatraviolet radiation
  • Produciton of keratin which protects from abrasion and serves as a water repellant
  • Synthesis of vitamin D3, a steroid which is subsequently converted into calcitriol, a hormone important to normal calcium metabolism
  • Store lipids in adipocytes in the dermis and in adipose tissue in the subcutaneous layer
  • Detect touch, pressure, pain and temperature stimuli, and reply that information to the nervous system
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5
Q

Skin is a ____ organ

A
  • composite
  • made of all tissue types
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6
Q

Primary layers of the skin

A
  • epidermis (cutaneous)
  • dermis (cutaneous)
  • hypodermics (subcutaneous)
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7
Q

Features of the epidermis

A
  • stratified barrier
  • mostly keratinocytes
  • no blood circulation (avascular)
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8
Q

Features of the dermis

A
  • protein fibres for strength (collagen and elastin)
  • vascular (nourishes epidermis)
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9
Q

Features of the hypodermis

A
  • adipose tissue
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10
Q
A
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11
Q

What is the predominant tissue of the epidermis

A

Epithelial tissue

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12
Q

What kind of epeithelia is the epidermis made of

A

Stratified squamous epithelium

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13
Q
A

Simple squamous

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14
Q
A

Simple Cuboidal

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15
Q
A

Simple columnar

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16
Q
A

Stratified squamous

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17
Q
A

Stratified cuboidal

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18
Q
A

Stratified columnar

19
Q

Layers of the epidermis (thin skin)

A

Stratum cornerman
Stratum granulosum
Stratum spinosum
Stratum basale

20
Q

Stratum cornerman

A
  • dead, dried out hard cells without nuclei
21
Q

Stratum granulosum

A
  • contain granules that promote dehydration of the cell, cross linking of keratin fibre
  • waxy material is secreted into the intercellular spaces
22
Q

Stratum spinosum

A
  • intercellular brindles called desmosomes link the cells together
  • the cells become increasingly flattened as they move upward
23
Q

Stratum basale

A
  • columnar (tall) regenerative cells
  • as the basal cell divides, a daughter cell migrates upwards to replenish the layer above
24
Q

Desmosomes

A

Anchours adjacent/ neighbouring cells in epidermis

25
Q

Hemidesmosomes

A

Anchors stratum basale to the dermis

26
Q

How thick skin differes from thin skin

A
  • no hair
  • extra epidermal layer (stratum lucidum)
27
Q

Where is thick skin found

A
  • palms of hands and soles of feet
28
Q

Layers of the epidermis (thick)

A

Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale

29
Q

Layers of epidermis

A

Stratum corneum
Stratum granulosum
Stratum spinosum
Stratum basale

30
Q
A
31
Q
A
32
Q

Features of the dermis

A
  • situated below the epidermis and anchors via hemidesmosomes
  • doesn’t get shed
  • divided into two layers: papillary layer and reticular layer
33
Q

Pappilary layer

A

Consists of highly vascularised tissues (for nourishment)

34
Q

Reticular layer

A

‘Mesh-like’ structure of collagen and elastin fibres (for strength)

35
Q

Similarities between reticular and papillary layer

A

Both layers contain:
- blood vessels
- lymphatics
- sensory nerve fibres
- accessory structures

36
Q

Plexuses of the dermis

A

Cutaneous plexus
Subpapillary plexus

37
Q

What is the cutaneous plexus and what does it do?

A
  • a network of blood vessels present at the junction of the dermis/ hypodermis
  • supplies the hypodermis, deeper dermis, including the capillaries for hair follicles and sweat glands
38
Q

Subpapillary plexus

A
  • branches from the cutaneous plexus
  • lies deep to the papillary layer of the dermis
  • network of blood vessels providing O2 and nutrients to the upper dermis and epidermis
39
Q

Features of the hypodermis

A
  • the subcutaneous layer
  • is a part of the skin
  • dominated by adipocytes that produce subcutaneous Fat
  • the subcutaneous fat stores energy and provides insulation
  • common site of injections using hypodermic needles
40
Q

First degree burn

A
  • superficial - only in love the outer layers of the epidermis
  • red/pink, dry, painful
  • usually no blisters e.g a mild sunburn
  • skin remains a water and bacterial barrier
  • usually heals 3-10 days
41
Q

Normal second degree burn

A
  • epidermis and varying amounts of dermis effected
  • painful, moist, red and blistered
  • usually heal in approx 1-2 weeks
42
Q

Deeper second degree burns

A
  • may include whiteish, waxy looking areas
  • hair follicles, sweat glands may remain intact
  • usually heal in one month
  • may have some loss of sensation and scarring
43
Q

Third degree burn

A
  • full thickness burns ie extend into subcutaneous tissue and may involve muscle and bone
  • varied colour from waxy white through to deep red or black
  • hard, dry and leathery skin
  • no pain in these areas as sensory nerve endings are destroyed
  • may require skin graftin
  • weeks to regenerate + scarring