lecture 5 exam 5 pt 2

Question 1

Difference between PMS and PMDD

Answer 1

PMS- 3-8% prevalence
must have atleast 1 symptoms of affective (emotional) or somatic (Physical) x 3 menstrual cycles

PMDD- 1.3-9% prevalence
included in DSM-5
- must have at least 5 symptoms with atleast 1 in 2 different categories for 2 consecutive months

Question 2

Similarities between PMS and PMDD

Answer 2

reduced levels of serotonin and GABA
fluctuations in estrogen and progesterone

Question 3

First line treatments of PMS and PMDD

Answer 3

SSRIs, NSAIDs, Spironolactone

Question 4

Second line treatments of PMS and PMDD in order

Answer 4

Venlafaxine, Duloxetine, Clomipramine, Alprazolam

Question 5

commonly used SSRIs for PMS/PMDD. When to strat and when to stop

Answer 5

fluoxetine, sertralne, paroxetine
start on day 14 on cycle
stop 1-2 days after onset of menses

Question 6

blackbox warning for SSRIs

Answer 6

Suicidal thinking. Improves in symptoms within 2-3 menstrual cycles

Question 7

What does spironolactone help with

Answer 7

decreased weight gain, decreased somatic symptoms (breast tenderness, bloating) and decreases negative mood

Question 8

What do SSRIs help the patients with

Answer 8

Mood/ emotional and physical symptoms