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Therapeutics > Final exam lecture 8 > Flashcards

Final exam lecture 8 Flashcards

1
Q

Lifestyle mods to avoid rosacea

A

Avoid triggers (sun, temperature,etc)
Mild soaps
topical meds should be allowed to penetrate the skin for 5-10 mins before make up

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2
Q

treatment of mild rosacea

A

avoid triggers
topical antibiotics
topical retinoids

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3
Q

treatment of moderate rosacea

A

Oral antibiotics
topical retinoids

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4
Q

Treatment of severe rosacea

A

Oral isotretinoin
laser treatment

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5
Q

1st choice for topical antimicrobial for rosacea

A

Metronidazole

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6
Q

topical retinoid drug used in rosacea

A

Azelaic acid

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7
Q

Psoriasis non-pcol treatments

A

Sun, baths, emollients

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8
Q

treatments of psoriasis + psoriatic arthritis

A

Biologic (anti-TNF, MTX)

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9
Q

Treatment of psoriasis without psoriatic arthritis

A

Topicals/photo therapy

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10
Q

Topical therapies for psoriasis

A

Corticosteroids
Calipotriene/calcitrol
Cort+ Vit D
Cort + tazarotene
Calcineurin inhibitors

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11
Q

Why do we limit corticosteroid use to 1 month at a time

A

Tachyphylaxis

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12
Q

How to avoid tachyphylaxis or corticosteroid when treating psoriasis

A

Alternate HCS with other agents (calcipotriene) to reduce exposure to corticosteroid

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13
Q

two types of phototherapy

A

UVA
UVB

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14
Q

Compare UVA and UVB

A

UVA penetrates thick lesions better than UVB
UVA is riskier than UVB

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15
Q

First line biologic therapy for severe psoriasis

A

TNF and T-cell activation inhibitors

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16
Q

Define Pediatric

A

birth to 18 years

17
Q

define neonate

A

0-28 days of life

18
Q

Define pre term and term labour

A

Pre-term- less than 37 weeks
term- 37 weeks gestational age

19
Q

Infant definition

A

1-12 months

20
Q

Child definition

A

1-11 yo

21
Q

adolescent definition

A

12-18 yo

22
Q

Define gestational age

A

Time from first day of last menstrual period to birth

23
Q

Define postnatal age (chronological age)

A

Birth to present

24
Q

Define postmenstrual age

A

first day of last menstrual period to present

25
Q

corrected age calculation

A

IF the baby was born normally (40 wks) how old would baby be?

26
Q

pediatric patients should grow

A

weight double by 4-6 months
weight triples by 12 months
length increases 50 percent by 12 months

27
Q

What happens to HR as infants grow

A

HR is v high in babies
Slows to adult levels over time

28
Q

What happens to BP as infants grow

A

It rises to adult levels

29
Q

What happens to RR as infabts grwo

A

It slows to adult levels

30
Q

When to refer for fever based on age

A

Under 3 months old- everyone
less than 2 yo- Fever>24 hrs
If older than 2 yo- fever greater than 104

31
Q

What are two OTC options for fever and pain for children

A

Acetaminophen
Ibuprofen (given only to children older than 6 months old)

32
Q

Dosing and max dosing of acetaminophen in children

A

10-15mg/kg Q4-6 H
max dose- 75 mg/kg/day or 4 g/day (whichever is lower)

33
Q

Dosing and max dose of ibuprofen in children

A

5-10 mg/kg/dose Q 6-8 H
GIVEN ONLY TO CHILDREN ABOVE 6 MONTHS OLD

max dose- 40 mg/kg/day

34
Q

Absorption difference between adults and neonates

A

Thinner skin layers in neonates- leads to stuff being easily absorbed
Slower enteral absorption
Increased gastric PH

35
Q

How does total body water % and total body fat change with age

A

Body fat increases, water decreases

36
Q

Protein binding in infants compared to adults

A

Decreased protein binding in babies

37
Q

Urine output (appropriate, oliguria, anuria) expectations

A

appropriate- 1 ml/kg/hr
oliguria- <0.5 ml/kg/h
anuria- 0

38
Q

creatinine clearence formula

A

0.413x (height in cm/Serum creatinine)

Therapeutics (46 decks)

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