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Therapeutics > FInal exam lecture 7 > Flashcards

FInal exam lecture 7 Flashcards

1
Q

Nam ethe 5 vehicles for dermatologic products

A

Ointment
cream
lotion
Gel
Spray/foam/solution

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2
Q

Advantage/disadvantage of Ointement

A

Adv- Best for hydration
Best for drug delivery
Removes scales

Dis- Greasy, low pt acceptance, not ideal for hairy areas

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3
Q

Adv/dis of creams

A

Adv- Good for hydration and drug delivery, high pt acceptance, can apply to most areas

No dis

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4
Q

Lotion adv/dis

A

Adv- Watered down creams, easy to apply good pt acceptance
dis- requires freq application, not ideal for very dry skin

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5
Q

Gel adv/dis

A

adv- high pt acceptance, excellent for EtOH soluble drugs, can apply to most sreas
Non- greasy

dis- can be drying

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6
Q

Adv/Dis of solutiuons, foams and sprays

A

Adv- can apply to most areas, easy to apply to hair areas
dis- drying
not ideal for drug delivery
not ideal for hydration
requires freq application

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7
Q

Main sx of acute contact dermatitis

A

Itching

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8
Q

Two types of acute contact dermatitis

A

Allergic
irritant

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9
Q

treatment of poison IVY

A

Remove source
Topical antihistamines/oral antihistamines
Topical/oral corticosteroids

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10
Q

Why are corticosteroids effective in treating acute dermatitis

A

Anti inflammatory characteristiscs

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11
Q

Dosing of corticosteroids in treating acute dermatitis

A

Apply BID to QID x 10-14 days

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12
Q

Dos and DONTS OF CORTICOSTEROID perscription

A

AVOID DOSE PACKET
start at prednisone 40-60 mg/day, taper every 3 days

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13
Q

most common cause of eczema

A

Atopic dermatitis

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14
Q

what is the atopic triad

A

Atopic dermatitis patients also develop allergic rhinitis and/or asthma.

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15
Q

How does atopic dermatitis differ from the other dermititis

A

It is symmetrical (bilateral)

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16
Q

common locations of atopic dermatitis in infants, children and adults

A

Infants- skin rash on cheeks and skin
Child- face, neck, creases of arms and legs
adults- hands and neck

17
Q

triggers of atopic dermatitis

A

Detergents, irritants

18
Q

stepwise treatment of atopic dermatitis

A

Non-pcol
topical
systemic

19
Q

Non pcol treatments of atopic dermatitis

A

Lukewarm/tepid baths with emollients
Eliminate irritants

20
Q

Topical therapies for atopic dermatitis

A

Topical corticosteroids
Topical calcineurin inhibitor
Topical JAK inhibitor

21
Q

Systemic therapy for atopic dermatitis

A

phototherapy, oral immunosuppresant therapy
Oral JAK inhibitors, injectibel biologic agents

22
Q

How to treat moderate-severe acute flares of atopic dermatitis

A

Medium potency TCS BID for 3 days neyond clearance of lesions

23
Q

What if the flares are refractory fro mod-severe atopic dermatitis

A

Phototherapy or immunosuppressive therapy

Inadequate response to all therapies consider biologics agents

24
Q

Classification of topical corticosteroids

A

Very high potency (class 1)- betamethasone (ointment) (not on face)
High potency (class 2)- bethmethasone cream (not on face)
Mid potency (class 3)- lotion

25
Q

Name topical calcineurin inhibitors

A

Pimecromilus and tacromilus, can be used on any area (equivalent to mid potency corts)

second line to corts

26
Q

Divide acne into two classes

A

Non-inflammatory (whiteheads, blackheads)
Inflammatory- Papules, pustules, ruptured contents

27
Q

most effective agent to treat Acne

A

Isotretinoin

28
Q

First choice treatments based on acne type

A

mild- topical retinoids (adapalene)
Mild- moderate : Adalapene+BP or clindamycin + BP
Severe or nodular/congloburate acne- Oral isotretinoin

29
Q

use of oral antibiotics in acne treatment

A

Decreases bacteria and inflammation, most effective when inflammation is present

Minocycline, doxycycline, erythromycin

30
Q

What is isotretinoin

A

Used for severe acne when patients have failed other tx.

31
Q

dosing of isotretinoin

A

0.5-2 mg/kg/day in 2 doses
Acne will get worse before it gets better

32
Q

Isoretinoin adverese effects

A

dry skin, lips and eyes, depression and suicide

33
Q

counseling tips for isotretinoin

A

avoid pregnancy/ use contraceptives and stop taking vit A supplements

Therapeutics (46 decks)

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