FInal exam lecture 7 Flashcards

1
Q

Nam ethe 5 vehicles for dermatologic products

A

Ointment
cream
lotion
Gel
Spray/foam/solution

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2
Q

Advantage/disadvantage of Ointement

A

Adv- Best for hydration
Best for drug delivery
Removes scales

Dis- Greasy, low pt acceptance, not ideal for hairy areas

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3
Q

Adv/dis of creams

A

Adv- Good for hydration and drug delivery, high pt acceptance, can apply to most areas

No dis

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4
Q

Lotion adv/dis

A

Adv- Watered down creams, easy to apply good pt acceptance
dis- requires freq application, not ideal for very dry skin

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5
Q

Gel adv/dis

A

adv- high pt acceptance, excellent for EtOH soluble drugs, can apply to most sreas
Non- greasy

dis- can be drying

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6
Q

Adv/Dis of solutiuons, foams and sprays

A

Adv- can apply to most areas, easy to apply to hair areas
dis- drying
not ideal for drug delivery
not ideal for hydration
requires freq application

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7
Q

Main sx of acute contact dermatitis

A

Itching

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8
Q

Two types of acute contact dermatitis

A

Allergic
irritant

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9
Q

treatment of poison IVY

A

Remove source
Topical antihistamines/oral antihistamines
Topical/oral corticosteroids

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10
Q

Why are corticosteroids effective in treating acute dermatitis

A

Anti inflammatory characteristiscs

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11
Q

Dosing of corticosteroids in treating acute dermatitis

A

Apply BID to QID x 10-14 days

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12
Q

Dos and DONTS OF CORTICOSTEROID perscription

A

AVOID DOSE PACKET
start at prednisone 40-60 mg/day, taper every 3 days

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13
Q

most common cause of eczema

A

Atopic dermatitis

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14
Q

what is the atopic triad

A

Atopic dermatitis patients also develop allergic rhinitis and/or asthma.

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15
Q

How does atopic dermatitis differ from the other dermititis

A

It is symmetrical (bilateral)

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16
Q

common locations of atopic dermatitis in infants, children and adults

A

Infants- skin rash on cheeks and skin
Child- face, neck, creases of arms and legs
adults- hands and neck

17
Q

triggers of atopic dermatitis

A

Detergents, irritants

18
Q

stepwise treatment of atopic dermatitis

A

Non-pcol
topical
systemic

19
Q

Non pcol treatments of atopic dermatitis

A

Lukewarm/tepid baths with emollients
Eliminate irritants

20
Q

Topical therapies for atopic dermatitis

A

Topical corticosteroids
Topical calcineurin inhibitor
Topical JAK inhibitor

21
Q

Systemic therapy for atopic dermatitis

A

phototherapy, oral immunosuppresant therapy
Oral JAK inhibitors, injectibel biologic agents

22
Q

How to treat moderate-severe acute flares of atopic dermatitis

A

Medium potency TCS BID for 3 days neyond clearance of lesions

23
Q

What if the flares are refractory fro mod-severe atopic dermatitis

A

Phototherapy or immunosuppressive therapy

Inadequate response to all therapies consider biologics agents

24
Q

Classification of topical corticosteroids

A

Very high potency (class 1)- betamethasone (ointment) (not on face)
High potency (class 2)- bethmethasone cream (not on face)
Mid potency (class 3)- lotion

25
Name topical calcineurin inhibitors
Pimecromilus and tacromilus, can be used on any area (equivalent to mid potency corts) second line to corts
26
Divide acne into two classes
Non-inflammatory (whiteheads, blackheads) Inflammatory- Papules, pustules, ruptured contents
27
most effective agent to treat Acne
Isotretinoin
28
First choice treatments based on acne type
mild- topical retinoids (adapalene) Mild- moderate : Adalapene+BP or clindamycin + BP Severe or nodular/congloburate acne- Oral isotretinoin
29
use of oral antibiotics in acne treatment
Decreases bacteria and inflammation, most effective when inflammation is present Minocycline, doxycycline, erythromycin
30
What is isotretinoin
Used for severe acne when patients have failed other tx.
31
dosing of isotretinoin
0.5-2 mg/kg/day in 2 doses Acne will get worse before it gets better
32
Isoretinoin adverese effects
dry skin, lips and eyes, depression and suicide
33
counseling tips for isotretinoin
avoid pregnancy/ use contraceptives and stop taking vit A supplements