Final lecture 9 Flashcards

1
Q

When can children swallow tablets and capsules

A

7-8 yo

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2
Q

Compare GER and GERD

A

GER (gastroesophageal reflux)- is the passage of gastric contents into the esophagus
GERD(gastroesophageal reflux disease) gastric reflux causes troublesome symptoms or complications

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3
Q

What is GER caused by

A

Relaxation of lower esophageal sphincter

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4
Q

symptom difference between infants and Children older than 4

A

Infants with reflux may be happy spitters or may be fussy.
Children older than 4 yo have classic heartburn symptoms similar to adults

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5
Q

GERD symptom in infants

A

1)Gastrointestinal
Regurgitation
feeding difficulties

2)Extra-intestinal
Irritability
back arching
persistent cough

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6
Q

Symotims of GERD in children

A

Heartburn
vomiting
regurgitation
dysphagia
chest pain

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7
Q

alarm symptoms for when to refer

A

Bilious or projectile emesis
GI bleeding/hematemesis
vomiting beginning after 6 months of age
difficulty swallowing
fever
diarrhea/constipation

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8
Q

non-pcol therapy for infant patients

A

feeding changes- thickening of food, increasing caloric density of feeds while decreasing volume

Positioning therapy- Keep upright after feeds.
Elevate head of bed

Lifestyle changes
Frequent burping, weight reduction, smaller or more frequent feeding

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9
Q

Treatment of GERD in older children

A

Diet/ positional modifications (same as infant)
Consider antacids for short term relief
Consider PPI for classic reflux symptoms

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10
Q

When do we consider using pharmacologic therapy in infants

A

Lifestyle mods not improving symotoms

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11
Q

What do we consider failure of lifestyle mods

A

no gain weight after 2-4 weeks

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12
Q

What are some available agents for pcol therapy of infants

A

Acid suppressants (H2RAs) (PPIs)
prokinetics
Antacids
consider weining after 4-8 weeks. No stopping suddenly

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13
Q

H2RA MOA

A

competitive inhibition of histamine at receptors on gastric parietal cells, results in decreased acid secretion

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14
Q

available agents for H2RA

A

famotidine

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15
Q

MOA of PPI

A

Irreversibly block gastric H/K/ATPase pumps
selectively inhibit H+ secretions

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16
Q

PPI dosing

A

1 mg/kg/day QD

17
Q

4 main pathways that an trigger vomiting

A

Bloodborne toxins (medications)
Motion (vestibular pathway)
Mechanical (vagal))
Emotion (fear, anxiety)

18
Q

Fecal impaction

A

Large fecal mass that is unlikely to be passed on command

19
Q

Encopresis definition

A

Fecal incontinence

20
Q

Normal stooling patters in infants, toddlers and 4 yo

A

Infants- 3-4 stools per day
toddler- 2-3 stools per day
4 yo adult patterns

21
Q

treatment of constipation in infants

A

1st line- glycerin suppositories (do not use for more than 3 days and has an onset of 30 mins)

22
Q

Treatment of constipation in children

A

1 (dispemaction).

Oral PEG (miralax)
1-1.5 g/kg/day x 3-6 days

  1. Maintainence
    PEG (miralax)

If no stool on mainatinence therapy, use Stimulants (senna, bisacodyl)

23
Q

Chronic diarrhea v diarrhea

A

Chronic is when lasting for more than 14 days
Diarrhea is 3 or more loose stools per day

24
Q

4 major categories of diarrhea in children

A

Secretory
osmotic
excretory
altered motility

25
Most common infectious disease in childrens diarrhea
Viral
26
Non infectious causes of diarrhea
Malabsorption short gut Allergic (lactose intolerance resolves by 12 mo) Over feeding medication
27
Most common drug induced cause of diarrhea
Antibiotics
28
if symptoms persist after antibiotics stopped consider______ as cause for infection
C. diff
29
Name of drug that causes diarrhea
Amoxicillin/clauvulanate Clauvulanate component causes diarrhea
30
Name the standard dose and the high dose of Amoxicillin/clauvulanate
standard dose- 40-50 mg/kg/day of amoxicillin component High dose- 80-90 mg/kg/day of amoxicillin component
31
Why should we use 600mg-42.9mg/5mL of amoxicillin/clavulanate
Has the highest ratio of amoxicillin to clavulanate we want to keep clavulanate less than 10 mg/kg/day
32
How do you calculate fluid requirements based on weight
Up to 10 Kg: 100 mL/kg 10-20:1000 mL+ 50 mL/kg for every Kg greater than 10 >20 kg: 1500 mL + 20 mL/kg for every kg greater than 20